Find Flurazepam Monohydrochloride manufacturers, exporters & distributors on PharmaCompass

PharmaCompass

Synopsis

Related ProductsRelated Products

Synopsis

ACTIVE PHARMA INGREDIENTS

0

USDMF

US DMFs Filed

0

JDMF

JDMFs Filed

0

KDMF

KDMF

0

NDC API

NDC API

0

VMF

NDC API

API REF. PRICE (USD/KG)

MARKET PLACE

0

API

0

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

0

FDF Dossiers

FDF Dossiers

0

FDA Orange Book

FDA (Orange Book)

0

Europe

Europe

0

Canada

Canada

0

Australia

Australia

0

South Africa

South Africa

0

Listed Dossiers

Listed Dossiers

0 DRUGS IN DEVELOPMENT

FDF Dossiers

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

0

EDQM

0

USP

0

JP

0

Others

PATENTS & EXCLUSIVITIES

0

US Patents

0

US Exclusivities

0

Health Canada Patents

DIGITAL CONTENT

0

Data Compilation #PharmaFlow

0

Stock Recap #PipelineProspector

0

Weekly News Recap #Phispers

0

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid

NA

Annual Reports

NA

Finished Drug Prices

NA

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

Click the arrow to open the dropdown
read-moreClick the button for full data set
Also known as: 36105-20-1, Dalmate, 7c4jh842ij, Dalmadorm, Dalmane, Felison
Molecular Formula
C21H24Cl2FN3O
Molecular Weight
424.3  g/mol
InChI Key
PUGVROXLRUQCAF-UHFFFAOYSA-N
FDA UNII
7C4JH842IJ

Flurazepam Monohydrochloride
A benzodiazepine derivative used mainly as a hypnotic.
1 2D Structure

Flurazepam Monohydrochloride

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
7-chloro-1-[2-(diethylamino)ethyl]-5-(2-fluorophenyl)-3H-1,4-benzodiazepin-2-one;hydrochloride
2.1.2 InChI
InChI=1S/C21H23ClFN3O.ClH/c1-3-25(4-2)11-12-26-19-10-9-15(22)13-17(19)21(24-14-20(26)27)16-7-5-6-8-18(16)23;/h5-10,13H,3-4,11-12,14H2,1-2H3;1H
2.1.3 InChI Key
PUGVROXLRUQCAF-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CCN(CC)CCN1C(=O)CN=C(C2=C1C=CC(=C2)Cl)C3=CC=CC=C3F.Cl
2.2 Other Identifiers
2.2.1 UNII
7C4JH842IJ
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Apo Flurazepam

2. Apo-flurazepam

3. Dalmadorm

4. Dalmane

5. Dihydrochloride, Flurazepam

6. Dormodor

7. Flurazepam

8. Flurazepam Dihydrochloride

9. Flurazepam Hydrochloride

10. Flurazepam Mono Perchlorate

11. Flurazepam Mono-perchlorate

12. Hydrochloride, Flurazepam

13. Mono-perchlorate, Flurazepam

14. Monohydrochloride, Flurazepam

15. Staurodorm

2.3.2 Depositor-Supplied Synonyms

1. 36105-20-1

2. Dalmate

3. 7c4jh842ij

4. Dalmadorm

5. Dalmane

6. Felison

7. Linzac

8. Natam

9. Insumin Dihydrochloride

10. 7-chloro-1-[2-(diethylamino)ethyl]-5-(2-fluorophenyl)-3h-1,4-benzodiazepin-2-one;hydrochloride

11. 2h-1,4-benzodiazepin-2-one, 7-chloro-1-(2-(diethylamino)ethyl)-5-(2-fluorophenyl)-1,3-dihydro-, Monohydrochloride

12. 7-chloro-1-[2-(diethylamino)ethyl]-5-(2-fluorophenyl)-1,3-dihydro-2h-benzo-1,4-diazepin-2-one Monohydrochloride

13. 7-chloro-1-(2-(diethylamino)ethyl)-5-(2-fluorophenyl)-1,3-dihydro-2h-benzo-1,4-diazepin-2-one Monohydrochloride

14. Id 480

15. Einecs 252-867-1

16. Unii-7c4jh842ij

17. Fluzepam

18. Dalmate (tn)

19. Fluorazepam Hydrochloride

20. Schembl29794

21. Chebi:31626

22. Flurazepam Hydrochloride (jp17)

23. Dtxsid40189686

24. Nsc78559

25. Flurazepam Monohydrochloride [mart.]

26. D01408

27. Flurazepam Monohydrochloride [ep Monograph]

28. Q27268050

29. Wln: T67 Gnv Jn Ihj Cg G2n2&2 Kr Bf &gh 2

30. 2h-1, 7-chloro-1-[2-(diethylamino)ethyl]-5-(2-fluorophenyl)-1,3-dihydro-, Dihydrochloride

31. 2h-1, 7-chloro-1-[2-(diethylamino)ethyl]-5-(o-fluorophenyl)-1,3-dihydro-, Dihydrochloride

32. 2h-1, 7-chloro-1-[2-(diethylamino)ethyl]-5-(o-fluorophenyl)-,1,3-dihydro-, Dihydrochloride

33. 2h-1,4-benzodiazepin-2-one, 7-chloro-1-(2-(diethylamino)ethyl)-5-(2-fluorophenyl)-1,3-dihydro-, Hydrochloride (1:1)

34. 7-chloro-1-[2-(diethylamino)ethyl]-5-(o-fluorophenyl)-1,4-benzodiazepin-2-one Dihydrochloride

35. Flurazepam Monohydrochloride; 7-chloro-1-[2-(diethylamino)ethyl]-5-(2-fluorophenyl)-1,3-dihydro-2h-benzo-1,4-diazepin-2-one Monohydrochloride; 2h-1,4-benzodiazepin-2-one, 7-chloro-1-[2-(diethylamino)ethyl]-5-(o-fluorophenyl)-,1,3-dihydro-, Dihydrochloride

2.4 Create Date
2005-06-24
3 Chemical and Physical Properties
Molecular Weight 424.3 g/mol
Molecular Formula C21H24Cl2FN3O
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count6
Exact Mass423.1280459 g/mol
Monoisotopic Mass423.1280459 g/mol
Topological Polar Surface Area35.9 Ų
Heavy Atom Count28
Formal Charge0
Complexity540
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Drug and Medication Information
4.1 Drug Information
1 of 2  
Drug NameFlurazepam hydrochloride
Drug LabelFlurazepam hydrochloride is chemically 7-chloro-1-[2-(diethylamino)ethyl]-5-(o-fluoro-phenyl)-1,3dihydro-2H-1,4-benzodiazepin-2-one dihydrochloride. It is a pale yellow, crystalline compound, freely soluble in alcohol and very soluble in water. It ha...
Active IngredientFlurazepam hydrochloride
Dosage FormCapsule
RouteOral
Strength30mg; 15mg
Market StatusPrescription
CompanyMylan Pharms

2 of 2  
Drug NameFlurazepam hydrochloride
Drug LabelFlurazepam hydrochloride is chemically 7-chloro-1-[2-(diethylamino)ethyl]-5-(o-fluoro-phenyl)-1,3dihydro-2H-1,4-benzodiazepin-2-one dihydrochloride. It is a pale yellow, crystalline compound, freely soluble in alcohol and very soluble in water. It ha...
Active IngredientFlurazepam hydrochloride
Dosage FormCapsule
RouteOral
Strength30mg; 15mg
Market StatusPrescription
CompanyMylan Pharms

5 Pharmacology and Biochemistry
5.1 MeSH Pharmacological Classification

GABA Modulators

Substances that do not act as agonists or antagonists but do affect the GAMMA-AMINOBUTYRIC ACID receptor-ionophore complex. GABA-A receptors (RECEPTORS, GABA-A) appear to have at least three allosteric sites at which modulators act: a site at which BENZODIAZEPINES act by increasing the opening frequency of GAMMA-AMINOBUTYRIC ACID-activated chloride channels; a site at which BARBITURATES act to prolong the duration of channel opening; and a site at which some steroids may act. GENERAL ANESTHETICS probably act at least partly by potentiating GABAergic responses, but they are not included here. (See all compounds classified as GABA Modulators.)


Anti-Anxiety Agents

Agents that alleviate ANXIETY, tension, and ANXIETY DISORDERS, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions. ADRENERGIC BETA-ANTAGONISTS are commonly used in the symptomatic treatment of anxiety but are not included here. (See all compounds classified as Anti-Anxiety Agents.)


Hypnotics and Sedatives

Drugs used to induce drowsiness or sleep or to reduce psychological excitement or anxiety. (See all compounds classified as Hypnotics and Sedatives.)


ABOUT THIS PAGE

Ask Us for Pharmaceutical Supplier and Partner
Ask Us, Find A Supplier / Partner
No Commissions, No Strings Attached, Get Connected for FREE

What are you looking for?

How can we help you?

The request can't be empty

Please read our Privacy Policy carefully

You must agree to the privacy policy

The name can't be empty
The company can't be empty.
The email can't be empty Please enter a valid email.
The mobile can't be empty