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    Givinostat

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    Angene International

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    Angene International

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    Givinostat

    About the Company : Angene is pledged to providing quality chemicals for use in research and development and commercial manufacturing. Angenes offers over 100,000 products including lab reagents, inte...

    Angene is pledged to providing quality chemicals for use in research and development and commercial manufacturing. Angenes offers over 100,000 products including lab reagents, intermediates, bulk commodities, agro-chemicals, natural ingredients and active pharmaceutical ingredients (APIs). In addition to the 100,000+ products, Angene offers custom synthesis of chemicals that are not commercially available.
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    J&H CHEM

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    J&H CHEM

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    About the Company : J&H CHEM is one of China's leading providers of integrated fine chemical services including offering, research and development, Custom manufacturing business, as well as other Valu...

    J&H CHEM is one of China's leading providers of integrated fine chemical services including offering, research and development, Custom manufacturing business, as well as other Value-added customer services, for diversified range products of chemicals, pharmaceuticals, and specialities. As a highly customer-oriented enterprise, we always believe "Customer first, service foremost", put forward innovation, continuously improve pipeline, integrate our broad range of products and services with our technical expertise, customise a competitive package to meet our customers' specific needs.
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    Taizhou Volsen Chemical

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    About the Company : Taizhou Volsen Chemical Co., Ltd. is professional in R&D, producing and marketing Pharmaceutical raw materials, pharmaceutical intermediates in China. VOLSEN consists of about 100 ...

    Taizhou Volsen Chemical Co., Ltd. is professional in R&D, producing and marketing Pharmaceutical raw materials, pharmaceutical intermediates in China. VOLSEN consists of about 100 experienced employees including 3 PhD and 10 Master, and 35000 sqm facilities including research laboratories, kilo lab, pilot plant and full manufacturing plant, VOLSEN R&D specialists, quality manager and sales with abundance experience make sure products are reliable and service is professional. The producing person inspect every step of the whole process and check up the quality strictly, in order to insure every batch of raw material achieve the standard of EP
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    Tian Yuan Pharm

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    About the Company : Tianyuan Pharmaceutical Co., Ltd. specializes in the research and development of targeted anticancer drugs and is dedicated to the exploration, production, and promotion of medical...

    Tianyuan Pharmaceutical Co., Ltd. specializes in the research and development of targeted anticancer drugs and is dedicated to the exploration, production, and promotion of medical raw materials. The company's primary product line includes Crizotinib, Afatinib, Capmatinib, Aloitinib, Sorafenib, Ibrutinib, Lenvatinib, Mirogabalin, Omarigliptin, Peficitinib, as well as various other types of TINI API and intermediates.Tianyuan has established stable collaboration with amplification plants in Jiaozhou, Qingdao, facilitating the scaling up of production from 100kg to tonnage quantities.
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    Looking for 497833-27-9 / Givinostat API manufacturers, exporters & distributors?

    Givinostat manufacturers, exporters & distributors 1

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    PharmaCompass offers a list of Givinostat API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Givinostat manufacturer or Givinostat supplier for your needs.

    Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Givinostat manufacturer or Givinostat supplier.

    PharmaCompass also assists you with knowing the Givinostat API Price utilized in the formulation of products. Givinostat API Price is not always fixed or binding as the Givinostat Price is obtained through a variety of data sources. The Givinostat Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

    API | Excipient name

    Givinostat

    Synonyms

    497833-27-9, Itf2357, Givinostat [inn], Givinostat free base, Itf-2357, [6-(diethylaminomethyl)naphthalen-2-yl]methyl n-[4-(hydroxycarbamoyl)phenyl]carbamate

    Cas Number

    497833-27-9

    Unique Ingredient Identifier (UNII)

    5P60F84FBH

    About Givinostat

    Givinostat is an orally bioavailable hydroxymate inhibitor of histone deacetylase (HDAC) with potential anti-inflammatory, anti-angiogenic, and antineoplastic activities. Givinostat inhibits class I and class II HDACs, resulting in an accumulation of highly acetylated histones, followed by the induction of chromatin remodeling and an altered pattern of gene expression. At low, nonapoptotic concentrations, this agent inhibits the production of pro-inflammatory cytokines such as tumor necrosis factor- (TNF-), interleukin-1 (IL-1), IL-6 and interferon-gamma. Givinostat has also been shown to activate the intrinsic apoptotic pathway, inducing apoptosis in hepatoma cells and leukemic cells. This agent may also exhibit anti-angiogenic activity, inhibiting the production of angiogenic factors such as IL-6 and vascular endothelial cell growth factor (VEGF) by bone marrow stromal cells.

    Givinostat Manufacturers

    A Givinostat manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Givinostat, including repackagers and relabelers. The FDA regulates Givinostat manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Givinostat API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

    click here to find a list of Givinostat manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

    Givinostat Suppliers

    A Givinostat supplier is an individual or a company that provides Givinostat active pharmaceutical ingredient (API) or Givinostat finished formulations upon request. The Givinostat suppliers may include Givinostat API manufacturers, exporters, distributors and traders.

    click here to find a list of Givinostat suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

    Givinostat Manufacturers | Traders | Suppliers

    Givinostat Manufacturers, Traders, Suppliers 1
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    We have 4 companies offering Givinostat

    Get in contact with the supplier of your choice:

    1. Angene International
    2. J&H CHEM
    3. Taizhou Volsen Chemical
    4. Tian Yuan Pharm
    Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
    For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.