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    Silatecan

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    Cohance Lifesciences

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    Virtual BoothCohance Lifesciences, offers full range of CDMO services for small molecule APIs, intermediates, ADCs, Pellets and Formulations.

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    Silatecan

    About the Company : Cohance Lifesciences is a leading CDMO and API platform, offering products and services across all phases of a molecule’s lifecycle from development to commercialzation. With our...

    Cohance Lifesciences is a leading CDMO and API platform, offering products and services across all phases of a molecule’s lifecycle from development to commercialzation. With our expertise in complex chemistries, we provide end-to-end CDMO services to global innovators and have delivered numerous projects from concept to commercialization over the years.As a global API player, we serve customers across nearly 60 countries with 80+ molecules backed by robust R&D, regulatory capabilities and manufacturing infrastructure. We are among the top backward integrated exporters of pellets and have strong development and manufacturing capabilities.
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    Looking for 220913-32-6 / Silatecan API manufacturers, exporters & distributors?

    Silatecan manufacturers, exporters & distributors 1

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    PharmaCompass offers a list of Silatecan API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Silatecan manufacturer or Silatecan supplier for your needs.

    Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Silatecan manufacturer or Silatecan supplier.

    PharmaCompass also assists you with knowing the Silatecan API Price utilized in the formulation of products. Silatecan API Price is not always fixed or binding as the Silatecan Price is obtained through a variety of data sources. The Silatecan Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

    API | Excipient name

    Silatecan

    Synonyms

    Ar-67, 220913-32-6, Db-67, Ar67, Db 67; silatecan, Db 67

    Cas Number

    220913-32-6

    Unique Ingredient Identifier (UNII)

    3YEA04NV6H

    About Silatecan

    Silatecan AR-67 is a synthetic, highly lipophilic derivative of camptothecin, with potential antineoplastic and radiosensitizing activities. 7-tert-butyldimethylsilyl-10-hydroxycamptothecin binds to and stabilizes the topoisomerase I-DNA covalent complex. This inhibits the religation of topoisomerase I-mediated single-stranded DNA breaks and produces lethal double-stranded DNA breaks when encountered by the DNA replication machinery, thereby inhibiting DNA replication and inducing apoptosis. Camptothecin readily undergoes hydrolysis at physiological pH, changing its conformation from the active lactone structure to an inactive carboxylate form. Modifications on the E ring of camptothecin prevent binding of human serum albumin, which prefers the inactive carboxylate form, thereby enhancing the stability of the active lactone structure and resulting in prolonged agent activity. In addition, this agent sensitizes tumor cells toward radiation treatment.

    Silatecan Manufacturers

    A Silatecan manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Silatecan, including repackagers and relabelers. The FDA regulates Silatecan manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Silatecan API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

    click here to find a list of Silatecan manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

    Silatecan Suppliers

    A Silatecan supplier is an individual or a company that provides Silatecan active pharmaceutical ingredient (API) or Silatecan finished formulations upon request. The Silatecan suppliers may include Silatecan API manufacturers, exporters, distributors and traders.

    click here to find a list of Silatecan suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

    Silatecan Manufacturers | Traders | Suppliers

    Silatecan Manufacturers, Traders, Suppliers 1
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    We have 1 companies offering Silatecan

    Get in contact with the supplier of your choice:

    1. Cohance Lifesciences
    Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
    For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.