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USDMF
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WC
Looking for 1762-34-1 / Abametapir API manufacturers, exporters & distributors?
Abametapir manufacturers, exporters & distributors
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API | Excipient name
Abametapir
Synonyms
1762-34-1, 5,5'-dimethyl-2,2'-bipyridine, 5,5'-dimethyl-2,2'-dipyridyl, 6,6'-bi-3-picoline, 5,5'-dimethyl-2,2'-bipyridyl, Xeglyze
Unique Ingredient Identifier (UNII)
6UO390AMFB
About Abametapir
Abametapir is a novel pediculicidal metalloproteinase inhibitor used to treat infestations of head lice. The life cycle of head lice (Pediculus capitis) is approximately 30 days, seven to twelve of which are spent as eggs laid on hair shafts near the scalp. Topical pediculicides generally lack adequate ovicidal activity, including standard-of-care treatments such as [permethrin], and many require a second administration 7-10 days following the first to kill newly hatched lice that resisted the initial treatment. The necessity for follow-up treatment may lead to challenges with patient adherence, and resistance to agents like permethrin and [pyrethrins]/[piperonyl butoxide] may be significant in some areas. Investigations into novel ovicidal treatments revealed that several metalloproteinase enzymes were critical to the egg hatching and survival of head lice, and these enzymes were therefore identified as a potential therapeutic target. Abemetapir is an inhibitor of these metalloproteinase enzymes, and the first topical pediculicide to take advantage of this novel target. The improved ovicidal activity (90-100% in vitro) of abemetapir allows for a single administration, in contrast to many other topical treatments, and its novel and relatively non-specific mechanism may help to curb the development of resistance to this agent. Abametapir was first approved for use in the United States under the brand name Xeglyze on July 27, 2020.
Abametapir Manufacturers
A Abametapir manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Abametapir, including repackagers and relabelers. The FDA regulates Abametapir manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Abametapir API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.
click here to find a list of Abametapir manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.
Abametapir Suppliers
A Abametapir supplier is an individual or a company that provides Abametapir active pharmaceutical ingredient (API) or Abametapir finished formulations upon request. The Abametapir suppliers may include Abametapir API manufacturers, exporters, distributors and traders.
click here to find a list of Abametapir suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.
Abametapir Manufacturers | Traders | Suppliers
Abametapir Manufacturers, Traders, Suppliers
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We have 1 companies offering Abametapir
Get in contact with the supplier of your choice:
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Viatris
Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.