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    Belumosudil

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    DMF Review : N/A

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    DMF Number : 40514

    Submission : 2024-09-29

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    Looking for 911417-87-3 / Belumosudil API manufacturers, exporters & distributors?

    Belumosudil manufacturers, exporters & distributors 1

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    PharmaCompass offers a list of Belumosudil API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Belumosudil manufacturer or Belumosudil supplier for your needs.

    Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Belumosudil manufacturer or Belumosudil supplier.

    PharmaCompass also assists you with knowing the Belumosudil API Price utilized in the formulation of products. Belumosudil API Price is not always fixed or binding as the Belumosudil Price is obtained through a variety of data sources. The Belumosudil Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

    API | Excipient name

    Belumosudil

    Synonyms

    911417-87-3, Slx-2119, Kd-025, Kd025, Rock inhibitor 2, Rezurock

    Cas Number

    911417-87-3

    Unique Ingredient Identifier (UNII)

    834YJF89WO

    About Belumosudil

    Belumosudil is an orally bioavailable inhibitor of Rho-associated coiled-coil kinase 2 (ROCK2; ROCK-II), with potential immunomodulating activity. Upon oral administration, belumosudil binds to and inhibits the serine/threonine kinase activity of ROCK2. This inhibits ROCK2-mediated signal transduction pathways and modulates various pro- and anti-inflammatory immune cell responses through the regulation of signal transducer and activator of transcription 3 and 5 (STAT3/STAT5) phosphorylation. This downregulates pro-inflammatory Th17 cells and increases regulatory T (Treg) cells. Belumosudil also inhibits ROCK2-mediated fibrotic processes, including stress fiber formation, myofibroblast activation and pro-fibrotic gene transcription. ROCK2 is upregulated in various diseases, including various fibrotic, neurodegenerative and autoimmune diseases.

    Belumosudil Manufacturers

    A Belumosudil manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Belumosudil, including repackagers and relabelers. The FDA regulates Belumosudil manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Belumosudil API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

    click here to find a list of Belumosudil manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

    Belumosudil Suppliers

    A Belumosudil supplier is an individual or a company that provides Belumosudil active pharmaceutical ingredient (API) or Belumosudil finished formulations upon request. The Belumosudil suppliers may include Belumosudil API manufacturers, exporters, distributors and traders.

    click here to find a list of Belumosudil suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

    Belumosudil Manufacturers | Traders | Suppliers

    Belumosudil Manufacturers, Traders, Suppliers 1
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    We have 2 companies offering Belumosudil

    Get in contact with the supplier of your choice:

    1. HRV Global Life Sciences
    2. TAPI Technology & API Services
    Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
    For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.