Elexacaftor/Ivacaftor/Tezacaftor API Manufacturers | Suppliers | Drug Master Files (DMF) | CEP

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01

Metrochem API Private Limited

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

MAGHREB PHARMA

Attending

Metrochem has been delivering customized volume & quality products to customers across the world, taking utmost care of their needs.

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India

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USDMF CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT

02

Aurobindo Pharma Limited

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

MAGHREB PHARMA

Not Confirmed

03

WuXi AppTec

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

MAGHREB PHARMA

Not Confirmed

04

Laurus Labs

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

MAGHREB PHARMA

Not Confirmed

05

Esteve Quimica

Spain

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

MAGHREB PHARMA

Not Confirmed

06

Medichem S.A

Spain

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

MAGHREB PHARMA

Not Confirmed

Looking for 2216712-66-0 / Elexacaftor API manufacturers, exporters & distributors?

PharmaCompass offers a list of Elexacaftor API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Elexacaftor manufacturer or Elexacaftor supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Elexacaftor manufacturer or Elexacaftor supplier.

PharmaCompass also assists you with knowing the Elexacaftor API Price utilized in the formulation of products. Elexacaftor API Price is not always fixed or binding as the Elexacaftor Price is obtained through a variety of data sources. The Elexacaftor Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Elexacaftor

Synonyms

2216712-66-0, Vx-445, Elexacaftor [usan], Rrn67gmb0v, Elexacaftor (usan), (s)-n-((1,3-dimethyl-1h-pyrazol-4-yl)sulfonyl)-6-(3-(3,3,3-trifluoro-2,2-dimethylpropoxy)-1h-pyrazol-1-yl)-2-(2,2,4-trimethylpyrrolidin-1-yl)nicotinamide

Cas Number

2216712-66-0

Unique Ingredient Identifier (UNII)

RRN67GMB0V

About Elexacaftor

Elexacaftor (previously VX-445) is a small molecule, next-generation corrector of the cystic fibrosis transmembrane conductance regulator (CFTR) protein. It received FDA approval in October 2019 in combination with [tezacaftor] and [ivacaftor] as the combination product TrikaftaTM. Elexacaftor is considered a next-generation CFTR corrector as it possesses both a different structure and mechanism as compared to first generation correctors like tezacaftor. While dual corrector/potentiator combination therapy has proven useful in the treatment of a subset of CF patients, their use is typically limited to patients who are homozygous for the F508del-CFTR gene. Elexacaftor, along with [VX-659], was designed to fill the need for an efficacious CF therapy for patients who are heterozygous for F508del-CFTR and a gene that does not produce protein or produces proteins unresponsive to ivacaftor or tezacaftor. The triple combination product TrikaftaTM, manufactured by Vertex Pharmaceuticals, is the first product approved for the treatment of CF in individuals who are either homo- or heterozygous for the F508del-CFTR gene - this represents approximately 70-90% of all CF patients.

Elexacaftor/Ivacaftor/Tezacaftor Manufacturers

A Elexacaftor/Ivacaftor/Tezacaftor manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Elexacaftor/Ivacaftor/Tezacaftor, including repackagers and relabelers. The FDA regulates Elexacaftor/Ivacaftor/Tezacaftor manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Elexacaftor/Ivacaftor/Tezacaftor API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Elexacaftor/Ivacaftor/Tezacaftor manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Elexacaftor/Ivacaftor/Tezacaftor Suppliers

A Elexacaftor/Ivacaftor/Tezacaftor supplier is an individual or a company that provides Elexacaftor/Ivacaftor/Tezacaftor active pharmaceutical ingredient (API) or Elexacaftor/Ivacaftor/Tezacaftor finished formulations upon request. The Elexacaftor/Ivacaftor/Tezacaftor suppliers may include Elexacaftor/Ivacaftor/Tezacaftor API manufacturers, exporters, distributors and traders.

click here to find a list of Elexacaftor/Ivacaftor/Tezacaftor suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Elexacaftor/Ivacaftor/Tezacaftor Manufacturers | Traders | Suppliers

We have 6 companies offering Elexacaftor/Ivacaftor/Tezacaftor

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Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.