Sodium Metaarsenite API Manufacturers | Suppliers | Drug Master Files (DMF) | CEP

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API | Excipient name

Sodium Metaarsenite

Synonyms

7784-46-5, Sodium dioxoarsenate, Sodium;oxoarsinite, Sodium meta-arsenite, Sodium (meta)arsenite, Arsenite, sodium

Cas Number

7784-46-5

Unique Ingredient Identifier (UNII)

48OVY2OC72

About Sodium Metaarsenite

Sodium Metaarsenite is a highly soluble, orally available trivalent arsenic-containing telomerase inhibitor with potential antitumor activity. Although the exact mechanism through which sodium metaarsenite exerts its effect has yet to be fully elucidated, this agent appears to target and bind to telomeric sequences, specifically TTAGGG repeats, leading to a shortening of telomeres, and subsequent induction of apoptosis and inhibition of tumor cell growth. In addition, sodium metaarsenite also leads to the translocation of the catalytic subunit of telomerase into the cytoplasm and inhibition of the activity of telomerase. Telomerase is active in most tumors cells and is responsible for the maintenance of telomere length and plays a key role in cellular proliferation, but is quiescent in normal, healthy cells. The susceptibility to sodium metaarsenite seems to be inversely correlated with initial length of telomeres.

Sodium Metaarsenite Manufacturers

A Sodium Metaarsenite manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Sodium Metaarsenite, including repackagers and relabelers. The FDA regulates Sodium Metaarsenite manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Sodium Metaarsenite API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Sodium Metaarsenite Suppliers

A Sodium Metaarsenite supplier is an individual or a company that provides Sodium Metaarsenite active pharmaceutical ingredient (API) or Sodium Metaarsenite finished formulations upon request. The Sodium Metaarsenite suppliers may include Sodium Metaarsenite API manufacturers, exporters, distributors and traders.

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Sodium Metaarsenite Manufacturers | Traders | Suppliers

We have 1 companies offering Sodium Metaarsenite

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Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.