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    Looking for Direct Compression? Find Direct Compression Agents used in Lesinurad to address drug delivery challenges on PharmaCompass.

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    Lesinurad

    ACTIVE PHARMA INGREDIENTS

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    01 1Alcedo Pharmachem

    02 16BASF

    03 1DFE Pharma

    04 4Microlex e.U

    05 6Sigachi Industries

    06 2The Dow Chemical Company

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    01

    DFE Pharma

    PHARMACEL 102

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    DFE Pharma

    Germany
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    Dosage Form : Tablet

    Grade : Oral

    Brand Name : Pharmacel 102

    Application : Direct Compression

    Excipient Details : Pharmacel® 102 has good flow properties enabling high speed direct compression tableting. It is a ideal choice for direct compression & dry granulation formulations and it also has some lubrication properties for smooth tableting experience.

    Pharmacopoeia Ref : Conforms to USP-NF, Ph.Eur., J...

    Technical Specs : Density- Tapped density- 440 g/l, Bulk density- 310 g/l; Particle size- D10- 40 ?m, D50- 90 ?m, D90-180 ?m; Hausner ratio-1,42

    Ingredient(s) : Microcrystalline Cellulose

    Dosage Form : Tablet

    Grade : Oral

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    Ingredient(s) : Microcrystalline Cellulose

    Dosage Form : Tablet

    Category : Direct Compression

    Brand : PHARMACEL 102

    Applications : Pharmacel® 102 has good flow properties enabling high speed direct compression tableting. It is a ideal choice for direct compression & dry granulation formulations and it also has some lubrication properties for smooth tableting experience.

    Pharmacopoeia Ref : Conforms to USP-NF, Ph.Eur., JP, IP

    Technical Specs : Density- Tapped density- 440 g/l, Bulk density- 310 g/l; Particle size- D10- 40 ?m, D50- 90 ?m, D90-180 ?m; Hausner ratio-1,42

    Grade : Oral

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    02

    Sigachi Industries

    ACECEL

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    Not Confirmed

    03

    Alcedo Pharmachem

    CSP

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    Not Confirmed

    04

    Sigachi Industries

    HICEL

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    Not Confirmed

    05

    Sigachi Industries

    HICEL HFE

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    Not Confirmed

    Sigachi Industries

    India
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    Dosage Form : Orodispersible Tablet

    Grade : Oral

    Brand Name : HiCel HFE

    Application : Direct Compression, Disintegrants & Superdisintegrants

    Excipient Details : HiCel HFE has various advantages such as Improved flow, Superior compactibility, low sensitivity to lubrication, better disintegration properties. It is used in direct compression of chewable tablets, fast dissolving tablets & mouth feel enhance...

    Pharmacopoeia Ref :

    Technical Specs :

    Ingredient(s) : Mannitol, Microcrystalline Cellulose

    Dosage Form : Orodispersible Tablet

    Grade : Oral

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    Ingredient(s) : Mannitol, Microcrystalline Cellulose

    Dosage Form : Orodispersible Tablet

    Category : Direct Compression, Disintegrants & Superdisintegrants

    Brand : HICEL HFE

    Applications : HiCel HFE has various advantages such as Improved flow, Superior compactibility, low sensitivity to lubrication, better disintegration properties. It is used in direct compression of chewable tablets, fast dissolving tablets & mouth feel enhancement.

    Pharmacopoeia Ref : Not Available

    Technical Specs : Not Available

    Grade : Oral

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    06

    The Dow Chemical Company

    METHOCEL™

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    The Dow Chemical Company

    U.S.A
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    Dosage Form : Tablet, Capsule

    Grade :

    Brand Name : METHOCEL™

    Application : API Stability Enhancers, Coating Systems & Additives, Controlled & Modified Release, Direct Compression, Granulation, Rheology Modifiers, Vegetarian Capsules

    Excipient Details : Controlled Release, Direct Compression,Wet Granulation,Tablet Coating, Liquid Solutions and Suspensions

    Pharmacopoeia Ref :

    Technical Specs :

    Ingredient(s) : Hydroxypropyl Methylcellulose

    Dosage Form : Tablet, Capsule

    Grade :

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    Ingredient(s) : Hydroxypropyl Methylcellulose

    Dosage Form : Tablet, Capsule

    Category : API Stability Enhancers, Coating Systems & Additives, Controlled & Modified Release, Direct Compression, Granulation, Rheology Modifiers, Vegetarian Capsules

    Brand : METHOCEL™

    Applications : Controlled Release, Direct Compression,Wet Granulation,Tablet Coating, Liquid Solutions and Suspensions

    Pharmacopoeia Ref : Not Available

    Technical Specs : Not Available

    Grade : Not Available

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    07

    Sigachi Industries

    HICELLAC

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    Sigachi Industries

    India
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    Dosage Form : Tablet

    Grade : Oral

    Brand Name : HiCellac

    Application : Direct Compression, Granulation

    Excipient Details : HiCellac 100 is used in direct compression, dry granulation & capsule filling, suitable for low dose formulations where API content uniformity is critical. It also provides excellent compaction properties & tablet hardness.

    Pharmacopoeia Ref :

    Technical Specs :

    Ingredient(s) : Lactose Monohydrate, Microcrystalline Cellulose

    Dosage Form : Tablet

    Grade : Oral

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    Ingredient(s) : Lactose Monohydrate, Microcrystalline Cellulose

    Dosage Form : Tablet

    Category : Direct Compression, Granulation

    Brand : HICELLAC

    Applications : HiCellac 100 is used in direct compression, dry granulation & capsule filling, suitable for low dose formulations where API content uniformity is critical. It also provides excellent compaction properties & tablet hardness.

    Pharmacopoeia Ref : Not Available

    Technical Specs : Not Available

    Grade : Oral

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    08

    Sigachi Industries

    HICEL SMCC

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    Not Confirmed

    09

    Microlex e.U

    MICROLEX® MCC 101

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    Not Confirmed

    10

    Microlex e.U

    MICROLEX® MCC 102

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    Microlex e.U

    Austria
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    Dosage Form : Tablet

    Grade : Oral

    Brand Name : Microlex® MCC 102

    Application : Direct Compression

    Excipient Details : The plastic defamation characteristics of  MCC 102 type mean that very hard tablets can be produced at light compaction forces, extending tooling lifetime and solving problems with poorly compressible actives.

    Pharmacopoeia Ref : Monograph- USP/NF, JP/JPE

    Technical Specs :

    Ingredient(s) : Microcrystalline Cellulose

    Dosage Form : Tablet

    Grade : Oral

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    Ingredient(s) : Microcrystalline Cellulose

    Dosage Form : Tablet

    Category : Direct Compression

    Brand : MICROLEX® MCC 102

    Applications : The plastic defamation characteristics of  MCC 102 type mean that very hard tablets can be produced at light compaction forces, extending tooling lifetime and solving problems with poorly compressible actives.

    Pharmacopoeia Ref : Monograph- USP/NF, JP/JPE

    Technical Specs : Not Available

    Grade : Oral

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    Microlex e.U

    MICROLEX® LCM 80.M

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    Microlex e.U

    Austria
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    Dosage Form : Tablet

    Grade : Oral

    Brand Name : Microlex® LCM 80.m

    Application : Direct Compression, Granulation

    Excipient Details : Lactose monohydrate is typically used for wet or dry granulation. During wet granulation, liquid binders or adhesives are added to the lactose and active mixture, usually by blending.

    Pharmacopoeia Ref : Monograph- USP/NF, JP/JPE

    Technical Specs : Milled; Also Available as Microlex® LCM 180.m, Microlex® LCM 200.m

    Ingredient(s) : Lactose Monohydrate

    Dosage Form : Tablet

    Grade : Oral

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    Ingredient(s) : Lactose Monohydrate

    Dosage Form : Tablet

    Category : Direct Compression, Granulation

    Brand : MICROLEX® LCM 80.M

    Applications : Lactose monohydrate is typically used for wet or dry granulation. During wet granulation, liquid binders or adhesives are added to the lactose and active mixture, usually by blending.

    Pharmacopoeia Ref : Monograph- USP/NF, JP/JPE

    Technical Specs : Milled; Also Available as Microlex® LCM 180.m, Microlex® LCM 200.m

    Grade : Oral

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    12

    Microlex e.U

    MICROLEX® LCM 120.S

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    Microlex e.U

    Austria
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    Dosage Form : Tablet

    Grade : Oral

    Brand Name : Microlex® LCM 120.s

    Application : Direct Compression, Granulation

    Excipient Details : It is also suitable for both wet granulation and direct compression methods of tablet production. Microlex® crystalline grades are used in wet granulation and the spray dried forms are used in direct compression.

    Pharmacopoeia Ref : Monograph- USP/NF, JP/JPE

    Technical Specs : Sieved; Also Available as Microlex® LCM 180.s, Microlex® LCM 220.s

    Ingredient(s) : Lactose Monohydrate

    Dosage Form : Tablet

    Grade : Oral

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    Ingredient(s) : Lactose Monohydrate

    Dosage Form : Tablet

    Category : Direct Compression, Granulation

    Brand : MICROLEX® LCM 120.S

    Applications : It is also suitable for both wet granulation and direct compression methods of tablet production. Microlex® crystalline grades are used in wet granulation and the spray dried forms are used in direct compression.

    Pharmacopoeia Ref : Monograph- USP/NF, JP/JPE

    Technical Specs : Sieved; Also Available as Microlex® LCM 180.s, Microlex® LCM 220.s

    Grade : Oral

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    13

    Sigachi Industries

    FILLERLAC

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    Not Confirmed

    14

    BASF

    LUDIPRESS

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    15

    BASF

    KOLLIDON CL

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    Not Confirmed

    16

    BASF

    KOLLIDON CL-M

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    Not Confirmed

    BASF

    Germany
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    Dosage Form : Capsule, Granule / Pellet, Tablet

    Grade :

    Brand Name : Kollidon CL-M

    Application : Direct Compression, Fillers, Diluents & Binders, Granulation

    Excipient Details : Roller compaction & direct compression including slight disintegration functionality, Reduces sedimentation in suspensions. Solubilizer in transdermal patches.

    Pharmacopoeia Ref : Ph. Eur., USP, JP: Crospovidon...

    Technical Specs :

    Ingredient(s) : Polyvinylpyrrolidone Crosslinked

    Dosage Form : Capsule, Granule / Pellet, Tablet

    Grade :

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    Ingredient(s) : Polyvinylpyrrolidone Crosslinked

    Dosage Form : Capsule, Granule / Pellet, Tablet

    Category : Direct Compression, Fillers, Diluents & Binders, Granulation

    Brand : KOLLIDON CL-M

    Applications : Roller compaction & direct compression including slight disintegration functionality, Reduces sedimentation in suspensions. Solubilizer in transdermal patches.

    Pharmacopoeia Ref : Ph. Eur., USP, JP: Crospovidone Type B

    Technical Specs : Not Available

    Grade : Not Available

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    BASF

    LUDIFLASH

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    Not Confirmed

    18

    BASF

    KOLLIDON CL-F

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    Not Confirmed

    BASF

    Germany
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    Dosage Form : Capsule, Granule / Pellet, Orodispersible Tablet, Tablet

    Grade :

    Brand Name : Kollidon CL-F

    Application : Chewable & Orodispersible Aids, Direct Compression, Disintegrants & Superdisintegrants

    Excipient Details : Kollidon CL-F has a balance of strong disintegration and optimal surface homogeneity.

    Pharmacopoeia Ref : Ph. Eur., USP, JP: Crospovidon...

    Technical Specs :

    Ingredient(s) : Polyvinylpyrrolidone Crosslinked

    Dosage Form : Capsule, Granule / Pellet, Orodispersible Tablet, Tablet

    Grade :

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    Ingredient(s) : Polyvinylpyrrolidone Crosslinked

    Dosage Form : Capsule, Granule / Pellet, Orodispersible Tablet, Tablet

    Category : Chewable & Orodispersible Aids, Direct Compression, Disintegrants & Superdisintegrants

    Brand : KOLLIDON CL-F

    Applications : Kollidon CL-F has a balance of strong disintegration and optimal surface homogeneity.

    Pharmacopoeia Ref : Ph. Eur., USP, JP: Crospovidone Type A

    Technical Specs : Not Available

    Grade : Not Available

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    19

    BASF

    KOLLIDON CL-SF

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    BASF

    Germany
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    Dosage Form : Granule / Pellet, Orodispersible Tablet, Tablet

    Grade :

    Brand Name : Kollidon CL-SF

    Application : Chewable & Orodispersible Aids, Direct Compression, Granulation

    Excipient Details : Kollidon CL-SF acts as a dry binder and super disintegrant suitable for small tablets and orally disintegrating tablets (ODTs). It provides pleasant mouthfeel due to finer particles.

    Pharmacopoeia Ref : Ph. Eur., USP, JP: Crospovidon...

    Technical Specs :

    Ingredient(s) : Polyvinylpyrrolidone Crosslinked

    Dosage Form : Granule / Pellet, Orodispersible Tablet, Tablet

    Grade :

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    Ingredient(s) : Polyvinylpyrrolidone Crosslinked

    Dosage Form : Granule / Pellet, Orodispersible Tablet, Tablet

    Category : Chewable & Orodispersible Aids, Direct Compression, Granulation

    Brand : KOLLIDON CL-SF

    Applications : Kollidon CL-SF acts as a dry binder and super disintegrant suitable for small tablets and orally disintegrating tablets (ODTs). It provides pleasant mouthfeel due to finer particles.

    Pharmacopoeia Ref : Ph. Eur., USP, JP: Crospovidone Type B

    Technical Specs : Not Available

    Grade : Not Available

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