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    Looking for Direct Compression? Find Direct Compression Agents used in Macimorelin to address drug delivery challenges on PharmaCompass.

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    01 Gangwal Healthcare (12)

    02 Alcedo Pharmachem (1)

    03 BASF (16)

    04 Microlex e.U (2)

    05 Sigachi Industries (3)

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    01 Capsule (9)

    02 Granule / Pellet (5)

    03 Orodispersible Tablet (3)

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    02 Germany (16)

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    Gangwal Healthcare

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      DICOM-DC® SR300

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      Applications:

      DiCOM-DC SR300 is used as a directly compressible, rate-controlling, and co-processed excipient in sustained-release tablets and capsules.

      Ingredient(s): EthylCellulose, Hydroxypropyl Cellulose, Hydroxypropyl Methylcellulose, Magnesium Stearate, Maize Starch, Microcrystalline Cellulose, Silicon Dioxide, Talc

      Dosage Form: Capsule, Tablet

      Category: Co-Processed Excipients, Controlled & Modified Release, Direct Compression

      Route of Administration (Grade): Oral
      Pharmacopoeia Reference: In-house

      Technical Specifications: NA

      Gangwal Healthcare DiCOM-DC® SR300

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      Gangwal Healthcare

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        LUBRISTAR™

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        Applications:

        Lubristar (Sodium Stearyl Fumarate) is used as a lubricant, disintegrant, and directly compressible excipient in tablets and capsules.

        Ingredient(s): Sodium Stearyl Fumarate

        Dosage Form: Capsule, Tablet

        Category: Direct Compression, Disintegrants & Superdisintegrants, Lubricants & Glidants

        Route of Administration (Grade): Oral
        Pharmacopoeia Reference: BP/EP/USP-NF

        Technical Specifications: NA

        Gangwal Healthcare Lubristar

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        Gangwal Healthcare

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          MICROLOSE™ M60 P60

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          Applications:

          Microlose M60 P60 is used as a filler, binder, directly compressible, and co-processed excipient in tablets and capsules.

          Ingredient(s): Lactose Monohydrate, Microcrystalline Cellulose

          Dosage Form: Capsule, Tablet

          Category: Co-Processed Excipients, Direct Compression, Fillers, Diluents & Binders

          Route of Administration (Grade): Oral
          Pharmacopoeia Reference: In-house

          Technical Specifications: Lactose Monohydrate – 40%, Microcrystalline cellulose – 60%

          Gangwal Healthcare CB

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          Gangwal Healthcare

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            LACTOSE DC

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            Applications:

            Lactose DC (Lactose Monohydrate) is used as a filler, binder, directly compressible, and co-processed excipient in tablets and capsules.

            Ingredient(s): Lactose Monohydrate

            Dosage Form: Capsule, Tablet

            Category: Co-Processed Excipients, Direct Compression, Fillers, Diluents & Binders

            Route of Administration (Grade): Oral
            Pharmacopoeia Reference: IP, USP

            Technical Specifications: NA

            Gangwal Healthcare Lactose DC

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              MICROLOSE® M25

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              Applications:

              Microlose® M25 is a co-processed DC excipient containing Lactose Monohydrate and Microcrystalline Cellulose that is used as a filler, binder, and disintegrant in oral solid dosage forms.

              Ingredient(s): Lactose Monohydrate, Microcrystalline Cellulose

              Dosage Form: Capsule, Tablet

              Category: Co-Processed Excipients, Direct Compression, Disintegrants & Superdisintegrants

              Route of Administration (Grade): Oral
              Pharmacopoeia Reference: In-house

              Technical Specifications: NA

              Gangwal Healthcare Microlose® M25

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              Gangwal Healthcare

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                STARLOSE® P40

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                Applications:

                STARLOSE® is a co-processed directly compressible (DC) excipient consisting of Maize Starch and Lactose Monohydrate which is used as a diluent and binding agent in oral solids.

                Ingredient(s): Lactose Monohydrate, Maize Starch

                Dosage Form: Capsule, Tablet

                Category: Co-Processed Excipients, Direct Compression, Fillers, Diluents & Binders

                Route of Administration (Grade): Oral
                Pharmacopoeia Reference: IP, EP, USP-NF

                Technical Specifications: NA

                Gangwal Healthcare STARLOSE® P40

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                Alcedo Pharmachem

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                  CSP

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                  Applications:

                  Crospovidone is an insoluble polymer of N-vinyl-2-pyrrolidone that is used as a disintegrant in pharmaceutical tablets.

                  Ingredient(s): Crospovidone

                  Dosage Form: Tablet

                  Category: Direct Compression, Disintegrants & Superdisintegrants

                  Route of Administration (Grade): Oral
                  Pharmacopoeia Reference: NA

                  Technical Specifications: NA
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                  Sigachi Industries

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                    HICELLAC

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                    Applications:

                    HiCellac 100 is used in direct compression, dry granulation & capsule filling, suitable for low dose formulations where API content uniformity is critical. It also provides excellent compaction properties & tablet hardness.

                    Ingredient(s): Lactose Monohydrate, Microcrystalline Cellulose

                    Dosage Form: Tablet

                    Category: Direct Compression, Granulation

                    Route of Administration (Grade): Oral
                    Pharmacopoeia Reference: Not Available

                    Technical Specifications: Not Available
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                    Sigachi Industries

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                      HICEL SMCC

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                      Applications:

                      HiCel SMCC has unique combination which result in optimum compaction & superior flow properties.

                      Ingredient(s): Microcrystalline Cellulose, Silicon Dioxide

                      Dosage Form: Tablet

                      Category: Direct Compression, Fillers, Diluents & Binders, Lubricants & Glidants

                      Route of Administration (Grade): Oral
                      Pharmacopoeia Reference: Not Available

                      Technical Specifications: Not Available
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                      Microlex e.U

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                        MICROLEX® LCM 80.M

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                        Applications:

                        Lactose monohydrate is typically used for wet or dry granulation. During wet granulation, liquid binders or adhesives are added to the lactose and active mixture, usually by blending.

                        Ingredient(s): Lactose Monohydrate

                        Dosage Form: Tablet

                        Category: Direct Compression, Granulation

                        Route of Administration (Grade): Oral
                        Pharmacopoeia Reference: Monograph- USP/NF, JP/JPE

                        Technical Specifications: Milled; Also Available as Microlex® LCM 180.m, Microlex® LCM 200.m
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                        Microlex e.U

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                          MICROLEX® LCM 120.S

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                          Applications:

                          It is also suitable for both wet granulation and direct compression methods of tablet production. Microlex® crystalline grades are used in wet granulation and the spray dried forms are used in direct compression.

                          Ingredient(s): Lactose Monohydrate

                          Dosage Form: Tablet

                          Category: Direct Compression, Granulation

                          Route of Administration (Grade): Oral
                          Pharmacopoeia Reference: Monograph- USP/NF, JP/JPE

                          Technical Specifications: Sieved; Also Available as Microlex® LCM 180.s, Microlex® LCM 220.s
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                          Sigachi Industries

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                            FILLERLAC

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                            Applications:

                            Lactose is widely used as a filler and diluent in tablets and capsules, and to a more limited extent in lyophilized products and infant formulas.

                            Ingredient(s): Lactose Monohydrate

                            Dosage Form: Tablet

                            Category: Direct Compression, Fillers, Diluents & Binders

                            Route of Administration (Grade): Oral and Parenteral
                            Pharmacopoeia Reference: Not Available

                            Technical Specifications: Not Available
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                            BASF

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                            LUDIPRESS

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                            Applications:

                            Ready-to-use direct compression solution for tablets.

                            Ingredient(s): Crospovidone, Lactose, Povidone

                            Dosage Form: Granule / Pellet, Tablet

                            Category: Direct Compression, Granulation

                            Route of Administration (Grade): Not Available
                            Pharmacopoeia Reference: Ph.Eur., USP/NF and JP

                            Technical Specifications: Not Available
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                            KOLLIDON CL

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                            Applications:

                            Maximum disintegration

                            Ingredient(s): Polyvinylpyrrolidone Crosslinked

                            Dosage Form: Capsule, Granule / Pellet, Tablet

                            Category: Direct Compression, Disintegrants & Superdisintegrants

                            Route of Administration (Grade): Not Available
                            Pharmacopoeia Reference: Ph. Eur., USP, JP: Crospovidone Type A

                            Technical Specifications: Not Available
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                            BASF

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                            KOLLIDON CL-M

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                            Applications:

                            Roller compaction & direct compression including slight disintegration functionality, Reduces sedimentation in suspensions. Solubilizer in transdermal patches.

                            Ingredient(s): Polyvinylpyrrolidone Crosslinked

                            Dosage Form: Capsule, Granule / Pellet, Tablet

                            Category: Direct Compression, Fillers, Diluents & Binders, Granulation

                            Route of Administration (Grade): Not Available
                            Pharmacopoeia Reference: Ph. Eur., USP, JP: Crospovidone Type B

                            Technical Specifications: Not Available
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                            BASF

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                            LUDIFLASH

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                            Applications:

                            Ludiflash is a ready-to-use orally disintegrating tablet (ODT) solution with superior mouthfeel.

                            Ingredient(s): Crospovidone, Mannitol, Polyvinyl Acetate

                            Dosage Form: Orodispersible Tablet

                            Category: Chewable & Orodispersible Aids, Direct Compression, Granulation

                            Route of Administration (Grade): Not Available
                            Pharmacopoeia Reference: Ph. Eur., USP, JP: 90 % mannitol, 5 % crospovidone, 5 % polyvinyl acetate

                            Technical Specifications: Not Available
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                            BASF

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                            KOLLIDON CL-F

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                            Applications:

                            Kollidon CL-F has a balance of strong disintegration and optimal surface homogeneity.

                            Ingredient(s): Polyvinylpyrrolidone Crosslinked

                            Dosage Form: Capsule, Granule / Pellet, Orodispersible Tablet, Tablet

                            Category: Chewable & Orodispersible Aids, Direct Compression, Disintegrants & Superdisintegrants

                            Route of Administration (Grade): Not Available
                            Pharmacopoeia Reference: Ph. Eur., USP, JP: Crospovidone Type A

                            Technical Specifications: Not Available
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                            KOLLIDON CL-SF

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                            Applications:

                            Kollidon CL-SF acts as a dry binder and super disintegrant suitable for small tablets and orally disintegrating tablets (ODTs). It provides pleasant mouthfeel due to finer particles.

                            Ingredient(s): Polyvinylpyrrolidone Crosslinked

                            Dosage Form: Granule / Pellet, Orodispersible Tablet, Tablet

                            Category: Chewable & Orodispersible Aids, Direct Compression, Granulation

                            Route of Administration (Grade): Not Available
                            Pharmacopoeia Reference: Ph. Eur., USP, JP: Crospovidone Type B

                            Technical Specifications: Not Available
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