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    Looking for Direct Compression? Find Direct Compression Agents used in Macitentan to address drug delivery challenges on PharmaCompass.

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    01 19Gangwal Healthcare

    02 8BASF

    03 1DFE Pharma

    04 2Gangwal Chemicals

    05 4Microlex e.U

    06 3Seppic

    07 6Sigachi Industries

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    01

    Gangwal Healthcare

    India
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    Virtual BoothGangwal Healthcare is powered by innovation, driving health, wellness & healing.

    Dosage Form : Capsule, Tablet

    Grade : Oral

    Brand Name : DiCOM-DC® SP204

    Application : Co-Processed Excipients, Direct Compression, Fillers, Diluents & Binders, Thickeners and Stabilizers

    Excipient Details : DiCOM-DC SP204 is used as a stabilizer, filler, binder, directly compressible, and co-processed excipient in tablets and capsules.

    Pharmacopoeia Ref : In-house

    Technical Specs : NA

    Ingredient(s) : Corn Starch, Pregelatinized, Magnesium Oxide Excipient, Microcrystalline Cellulose, Sodium Starch Glycolate

    Dosage Form : Capsule, Tablet

    Grade : Oral

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    Ingredient(s) : Corn Starch, Pregelatinized, Magnesium Oxide Excipient, Microcrystalline Cellulose, Sodium Starch Glycolate

    Dosage Form : Capsule, Tablet

    Category : Co-Processed Excipients, Direct Compression, Fillers, Diluents & Binders, Thickeners and Stabilizers

    Brand : DICOM-DC® SP204

    Applications : DiCOM-DC SP204 is used as a stabilizer, filler, binder, directly compressible, and co-processed excipient in tablets and capsules.

    Pharmacopoeia Ref : In-house

    Technical Specs : NA

    Grade : Oral

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    Gangwal Healthcare DiCOM-DC® SP204

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    Gangwal Healthcare

    India
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    Virtual BoothGangwal Healthcare is powered by innovation, driving health, wellness & healing.

    Dosage Form : Capsule, Granule / Pellet, Tablet

    Grade : Oral

    Brand Name : Solvostar™

    Application : Direct Compression, Disintegrants & Superdisintegrants

    Excipient Details : Solvostar (Sodium Starch Glycolate) is used as a superdisintegrant and directly compressible excipient in tablets, capsules, suspensions, and pellets.

    Pharmacopoeia Ref : IP/BP/EP/USP-NF

    Technical Specs : Solvostar 2% to 8%

    Ingredient(s) : Sodium Starch Glycolate

    Dosage Form : Capsule, Granule / Pellet, Tablet

    Grade : Oral

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    Ingredient(s) : Sodium Starch Glycolate

    Dosage Form : Capsule, Granule / Pellet, Tablet

    Category : Direct Compression, Disintegrants & Superdisintegrants

    Brand : SOLVOSTAR™

    Applications : Solvostar (Sodium Starch Glycolate) is used as a superdisintegrant and directly compressible excipient in tablets, capsules, suspensions, and pellets.

    Pharmacopoeia Ref : IP/BP/EP/USP-NF

    Technical Specs : Solvostar 2% to 8%

    Grade : Oral

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    Gangwal Healthcare

    India
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    Virtual BoothGangwal Healthcare is powered by innovation, driving health, wellness & healing.

    Dosage Form : Capsule, Tablet

    Grade : Oral

    Brand Name : ProBlend®

    Application : Co-Processed Excipients, Direct Compression, Disintegrants & Superdisintegrants, Fillers, Diluents & Binders, Lubricants & Glidants

    Excipient Details : ProBlend (Microcrystalline Cellulose) is used as a filler, binder, glidant, DC & co-processed excipient in tablets, capsules, and MUPS formulations.

    Pharmacopoeia Ref : USP-NF

    Technical Specs : NA

    Ingredient(s) : Microcrystalline Cellulose

    Dosage Form : Capsule, Tablet

    Grade : Oral

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    Ingredient(s) : Microcrystalline Cellulose

    Dosage Form : Capsule, Tablet

    Category : Co-Processed Excipients, Direct Compression, Disintegrants & Superdisintegrants, Fillers, Diluents & Binders, Lubricants & Glidants

    Brand : PROBLEND®

    Applications : ProBlend (Microcrystalline Cellulose) is used as a filler, binder, glidant, DC & co-processed excipient in tablets, capsules, and MUPS formulations.

    Pharmacopoeia Ref : USP-NF

    Technical Specs : NA

    Grade : Oral

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    Gangwal Healthcare ProBlend®

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    Gangwal Healthcare

    India
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    Virtual BoothGangwal Healthcare is powered by innovation, driving health, wellness & healing.

    Dosage Form : Capsule, Tablet

    Grade : Oral

    Brand Name : STARLOSE®

    Application : Co-Processed Excipients, Direct Compression, Fillers, Diluents & Binders

    Excipient Details : STARLOSE is used as a diluent, binder, directly compressible (DC), and co-processed excipient in tablets and capsules.

    Pharmacopoeia Ref : IP/EP/USP-NF/IH

    Technical Specs : NA

    Ingredient(s) : Lactose Monohydrate, Maize Starch

    Dosage Form : Capsule, Tablet

    Grade : Oral

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    Ingredient(s) : Lactose Monohydrate, Maize Starch

    Dosage Form : Capsule, Tablet

    Category : Co-Processed Excipients, Direct Compression, Fillers, Diluents & Binders

    Brand : STARLOSE®

    Applications : STARLOSE is used as a diluent, binder, directly compressible (DC), and co-processed excipient in tablets and capsules.

    Pharmacopoeia Ref : IP/EP/USP-NF/IH

    Technical Specs : NA

    Grade : Oral

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    Gangwal Healthcare

    India
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    Virtual BoothGangwal Healthcare is powered by innovation, driving health, wellness & healing.

    Dosage Form : Capsule, Tablet

    Grade : Oral

    Brand Name : Microlose™ M60 P60

    Application : Co-Processed Excipients, Direct Compression, Fillers, Diluents & Binders

    Excipient Details : Microlose M60 P60 is used as a filler, binder, directly compressible, and co-processed excipient in tablets and capsules.

    Pharmacopoeia Ref : In-house

    Technical Specs : Lactose Monohydrate – 40%, Microcrystalline cellulose – 60%

    Ingredient(s) : Lactose Monohydrate, Microcrystalline Cellulose

    Dosage Form : Capsule, Tablet

    Grade : Oral

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    Ingredient(s) : Lactose Monohydrate, Microcrystalline Cellulose

    Dosage Form : Capsule, Tablet

    Category : Co-Processed Excipients, Direct Compression, Fillers, Diluents & Binders

    Brand : MICROLOSE™ M60 P60

    Applications : Microlose M60 P60 is used as a filler, binder, directly compressible, and co-processed excipient in tablets and capsules.

    Pharmacopoeia Ref : In-house

    Technical Specs : Lactose Monohydrate – 40%, Microcrystalline cellulose – 60%

    Grade : Oral

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    Gangwal Healthcare

    India
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    Virtual BoothGangwal Healthcare is powered by innovation, driving health, wellness & healing.

    Dosage Form : Capsule, Tablet

    Grade : Oral

    Brand Name : DiCOM-DC® SR300

    Application : Co-Processed Excipients, Controlled & Modified Release, Direct Compression

    Excipient Details : DiCOM-DC SR300 is used as a directly compressible, rate-controlling, and co-processed excipient in sustained-release tablets and capsules.

    Pharmacopoeia Ref : In-house

    Technical Specs : NA

    Ingredient(s) : EthylCellulose, Hydroxypropyl Cellulose, Hydroxypropyl Methylcellulose, Magnesium Stearate, Maize Starch, Microcrystalline Cellulose, Silicon Dioxide, Talc

    Dosage Form : Capsule, Tablet

    Grade : Oral

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    Virtual BoothGangwal Healthcare is powered by innovation, driving health, wellness & healing.

    Ingredient(s) : EthylCellulose, Hydroxypropyl Cellulose, Hydroxypropyl Methylcellulose, Magnesium Stearate, Maize Starch, Microcrystalline Cellulose, Silicon Dioxide, Talc

    Dosage Form : Capsule, Tablet

    Category : Co-Processed Excipients, Controlled & Modified Release, Direct Compression

    Brand : DICOM-DC® SR300

    Applications : DiCOM-DC SR300 is used as a directly compressible, rate-controlling, and co-processed excipient in sustained-release tablets and capsules.

    Pharmacopoeia Ref : In-house

    Technical Specs : NA

    Grade : Oral

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    Gangwal Healthcare

    India
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    Virtual BoothGangwal Healthcare is powered by innovation, driving health, wellness & healing.

    Dosage Form : Capsule, Tablet

    Grade : Oral

    Brand Name : DiCOM-DC® PL009 P60

    Application : Co-Processed Excipients, Direct Compression, Fillers, Diluents & Binders

    Excipient Details : DiCOM-DC PL009 P60 is used as a filler, binder, directly compressible, and co-processed excipient in tablets and capsules.

    Pharmacopoeia Ref : IH

    Technical Specs : NA

    Ingredient(s) : Maize Starch, Microcrystalline Cellulose

    Dosage Form : Capsule, Tablet

    Grade : Oral

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    Ingredient(s) : Maize Starch, Microcrystalline Cellulose

    Dosage Form : Capsule, Tablet

    Category : Co-Processed Excipients, Direct Compression, Fillers, Diluents & Binders

    Brand : DICOM-DC® PL009 P60

    Applications : DiCOM-DC PL009 P60 is used as a filler, binder, directly compressible, and co-processed excipient in tablets and capsules.

    Pharmacopoeia Ref : IH

    Technical Specs : NA

    Grade : Oral

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    Gangwal Healthcare

    India
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    Virtual BoothGangwal Healthcare is powered by innovation, driving health, wellness & healing.

    Dosage Form : Capsule, Tablet

    Grade : Oral

    Brand Name : DiCOM-DC® S604

    Application : Co-Processed Excipients, Direct Compression, Fillers, Diluents & Binders

    Excipient Details : DiCOM-DC S604 is used as a DC co-processed excipient with a combination of various polymers that act as fillers and binders in tablets and capsules.

    Pharmacopoeia Ref : In-house

    Technical Specs : Polyvinyl Pyrrolidone 97% & 93%

    Ingredient(s) : Calcium Carbonate Excipient, Polyvinyl pyrrolidone

    Dosage Form : Capsule, Tablet

    Grade : Oral

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    Ingredient(s) : Calcium Carbonate Excipient, Polyvinyl pyrrolidone

    Dosage Form : Capsule, Tablet

    Category : Co-Processed Excipients, Direct Compression, Fillers, Diluents & Binders

    Brand : DICOM-DC® S604

    Applications : DiCOM-DC S604 is used as a DC co-processed excipient with a combination of various polymers that act as fillers and binders in tablets and capsules.

    Pharmacopoeia Ref : In-house

    Technical Specs : Polyvinyl Pyrrolidone 97% & 93%

    Grade : Oral

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    09

    Gangwal Healthcare

    India
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    Virtual BoothGangwal Healthcare is powered by innovation, driving health, wellness & healing.

    Dosage Form : Capsule, Tablet

    Grade : Oral

    Brand Name : Lactose DC

    Application : Co-Processed Excipients, Direct Compression, Fillers, Diluents & Binders

    Excipient Details : Lactose DC (Lactose Monohydrate) is used as a filler, binder, directly compressible, and co-processed excipient in tablets and capsules.

    Pharmacopoeia Ref : IP, USP

    Technical Specs : NA

    Ingredient(s) : Lactose Monohydrate

    Dosage Form : Capsule, Tablet

    Grade : Oral

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    Ingredient(s) : Lactose Monohydrate

    Dosage Form : Capsule, Tablet

    Category : Co-Processed Excipients, Direct Compression, Fillers, Diluents & Binders

    Brand : LACTOSE DC

    Applications : Lactose DC (Lactose Monohydrate) is used as a filler, binder, directly compressible, and co-processed excipient in tablets and capsules.

    Pharmacopoeia Ref : IP, USP

    Technical Specs : NA

    Grade : Oral

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    10

    DFE Pharma

    PHARMACEL 102

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    DFE Pharma

    Germany
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    Dosage Form : Tablet

    Grade : Oral

    Brand Name : Pharmacel 102

    Application : Direct Compression

    Excipient Details : Pharmacel® 102 has good flow properties enabling high speed direct compression tableting. It is a ideal choice for direct compression & dry granulation formulations and it also has some lubrication properties for smooth tableting experience.

    Pharmacopoeia Ref : Conforms to USP-NF, Ph.Eur., J...

    Technical Specs : Density- Tapped density- 440 g/l, Bulk density- 310 g/l; Particle size- D10- 40 ?m, D50- 90 ?m, D90-180 ?m; Hausner ratio-1,42

    Ingredient(s) : Microcrystalline Cellulose

    Dosage Form : Tablet

    Grade : Oral

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    Ingredient(s) : Microcrystalline Cellulose

    Dosage Form : Tablet

    Category : Direct Compression

    Brand : PHARMACEL 102

    Applications : Pharmacel® 102 has good flow properties enabling high speed direct compression tableting. It is a ideal choice for direct compression & dry granulation formulations and it also has some lubrication properties for smooth tableting experience.

    Pharmacopoeia Ref : Conforms to USP-NF, Ph.Eur., JP, IP

    Technical Specs : Density- Tapped density- 440 g/l, Bulk density- 310 g/l; Particle size- D10- 40 ?m, D50- 90 ?m, D90-180 ?m; Hausner ratio-1,42

    Grade : Oral

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    11

    BASF

    KOLLIDON SR

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    BASF

    Germany
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    Dosage Form : Capsule, Tablet, Topical Film, Transdermal Patch

    Grade :

    Brand Name : Kollidon SR

    Application : Controlled & Modified Release, Direct Compression, Granulation

    Excipient Details : For non-erodible matrices using direct compression, Controlled release matrix. Matrix former in transdermal patches and topical films.

    Pharmacopoeia Ref : Ph. Eur., USP-NF, JP-JPE: 80 %...

    Technical Specs :

    Ingredient(s) : Hydrated Silica, Lauryl Sulfate, Polyvinyl Acetate, Povidone

    Dosage Form : Capsule, Tablet, Topical Film, Transdermal Patch

    Grade :

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    Ingredient(s) : Hydrated Silica, Lauryl Sulfate, Polyvinyl Acetate, Povidone

    Dosage Form : Capsule, Tablet, Topical Film, Transdermal Patch

    Category : Controlled & Modified Release, Direct Compression, Granulation

    Brand : KOLLIDON SR

    Applications : For non-erodible matrices using direct compression, Controlled release matrix. Matrix former in transdermal patches and topical films.

    Pharmacopoeia Ref : Ph. Eur., USP-NF, JP-JPE: 80 % Polyvinyl acetate and 19 % povidone, 0.8 % lauryl sulfate & 0.2 % silica (4:1)

    Technical Specs : Not Available

    Grade : Not Available

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    Sigachi Industries

    ACECEL

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    13

    Sigachi Industries

    HICEL

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    Not Confirmed

    14

    Sigachi Industries

    HICEL HFE

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    Not Confirmed

    Sigachi Industries

    India
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    Dosage Form : Orodispersible Tablet

    Grade : Oral

    Brand Name : HiCel HFE

    Application : Direct Compression, Disintegrants & Superdisintegrants

    Excipient Details : HiCel HFE has various advantages such as Improved flow, Superior compactibility, low sensitivity to lubrication, better disintegration properties. It is used in direct compression of chewable tablets, fast dissolving tablets & mouth feel enhance...

    Pharmacopoeia Ref :

    Technical Specs :

    Ingredient(s) : Mannitol, Microcrystalline Cellulose

    Dosage Form : Orodispersible Tablet

    Grade : Oral

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    Ingredient(s) : Mannitol, Microcrystalline Cellulose

    Dosage Form : Orodispersible Tablet

    Category : Direct Compression, Disintegrants & Superdisintegrants

    Brand : HICEL HFE

    Applications : HiCel HFE has various advantages such as Improved flow, Superior compactibility, low sensitivity to lubrication, better disintegration properties. It is used in direct compression of chewable tablets, fast dissolving tablets & mouth feel enhancement.

    Pharmacopoeia Ref : Not Available

    Technical Specs : Not Available

    Grade : Oral

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    Sigachi Industries

    HICELLAC

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    India
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    Dosage Form : Tablet

    Grade : Oral

    Brand Name : HiCellac

    Application : Direct Compression, Granulation

    Excipient Details : HiCellac 100 is used in direct compression, dry granulation & capsule filling, suitable for low dose formulations where API content uniformity is critical. It also provides excellent compaction properties & tablet hardness.

    Pharmacopoeia Ref :

    Technical Specs :

    Ingredient(s) : Lactose Monohydrate, Microcrystalline Cellulose

    Dosage Form : Tablet

    Grade : Oral

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    Ingredient(s) : Lactose Monohydrate, Microcrystalline Cellulose

    Dosage Form : Tablet

    Category : Direct Compression, Granulation

    Brand : HICELLAC

    Applications : HiCellac 100 is used in direct compression, dry granulation & capsule filling, suitable for low dose formulations where API content uniformity is critical. It also provides excellent compaction properties & tablet hardness.

    Pharmacopoeia Ref : Not Available

    Technical Specs : Not Available

    Grade : Oral

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    Sigachi Industries

    HICEL SMCC

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    17

    Microlex e.U

    MICROLEX® MCC 101

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    18

    Microlex e.U

    MICROLEX® MCC 102

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    Microlex e.U

    Austria
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    Dosage Form : Tablet

    Grade : Oral

    Brand Name : Microlex® MCC 102

    Application : Direct Compression

    Excipient Details : The plastic defamation characteristics of  MCC 102 type mean that very hard tablets can be produced at light compaction forces, extending tooling lifetime and solving problems with poorly compressible actives.

    Pharmacopoeia Ref : Monograph- USP/NF, JP/JPE

    Technical Specs :

    Ingredient(s) : Microcrystalline Cellulose

    Dosage Form : Tablet

    Grade : Oral

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    Ingredient(s) : Microcrystalline Cellulose

    Dosage Form : Tablet

    Category : Direct Compression

    Brand : MICROLEX® MCC 102

    Applications : The plastic defamation characteristics of  MCC 102 type mean that very hard tablets can be produced at light compaction forces, extending tooling lifetime and solving problems with poorly compressible actives.

    Pharmacopoeia Ref : Monograph- USP/NF, JP/JPE

    Technical Specs : Not Available

    Grade : Oral

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    Microlex e.U

    MICROLEX® LCM 80.M

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    Microlex e.U

    Austria
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    Dosage Form : Tablet

    Grade : Oral

    Brand Name : Microlex® LCM 80.m

    Application : Direct Compression, Granulation

    Excipient Details : Lactose monohydrate is typically used for wet or dry granulation. During wet granulation, liquid binders or adhesives are added to the lactose and active mixture, usually by blending.

    Pharmacopoeia Ref : Monograph- USP/NF, JP/JPE

    Technical Specs : Milled; Also Available as Microlex® LCM 180.m, Microlex® LCM 200.m

    Ingredient(s) : Lactose Monohydrate

    Dosage Form : Tablet

    Grade : Oral

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    Ingredient(s) : Lactose Monohydrate

    Dosage Form : Tablet

    Category : Direct Compression, Granulation

    Brand : MICROLEX® LCM 80.M

    Applications : Lactose monohydrate is typically used for wet or dry granulation. During wet granulation, liquid binders or adhesives are added to the lactose and active mixture, usually by blending.

    Pharmacopoeia Ref : Monograph- USP/NF, JP/JPE

    Technical Specs : Milled; Also Available as Microlex® LCM 180.m, Microlex® LCM 200.m

    Grade : Oral

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    20

    Microlex e.U

    MICROLEX® LCM 120.S

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    Microlex e.U

    Austria
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    Dosage Form : Tablet

    Grade : Oral

    Brand Name : Microlex® LCM 120.s

    Application : Direct Compression, Granulation

    Excipient Details : It is also suitable for both wet granulation and direct compression methods of tablet production. Microlex® crystalline grades are used in wet granulation and the spray dried forms are used in direct compression.

    Pharmacopoeia Ref : Monograph- USP/NF, JP/JPE

    Technical Specs : Sieved; Also Available as Microlex® LCM 180.s, Microlex® LCM 220.s

    Ingredient(s) : Lactose Monohydrate

    Dosage Form : Tablet

    Grade : Oral

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    Ingredient(s) : Lactose Monohydrate

    Dosage Form : Tablet

    Category : Direct Compression, Granulation

    Brand : MICROLEX® LCM 120.S

    Applications : It is also suitable for both wet granulation and direct compression methods of tablet production. Microlex® crystalline grades are used in wet granulation and the spray dried forms are used in direct compression.

    Pharmacopoeia Ref : Monograph- USP/NF, JP/JPE

    Technical Specs : Sieved; Also Available as Microlex® LCM 180.s, Microlex® LCM 220.s

    Grade : Oral

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    Sigachi Industries

    FILLERLAC

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    BASF

    LUDIPRESS

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    BASF

    LUDIPRESS LCE

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    Seppic

    SEPITRAP 80

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    Gangwal Chemicals

    SEPITRAP 80

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    Gangwal Chemicals

    India
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    Dosage Form : Tablet, Capsule

    Grade : Oral

    Brand Name : SEPITRAP 80

    Application : API Stability Enhancers, Direct Compression, Solubilizers

    Excipient Details : Polysorbate 80 in dry powder form, a solubilizing agent acts as a surfactant and increases the solubility of various oral dosage forms.

    Pharmacopoeia Ref : USP-NF, EP, JP & having US DMF

    Technical Specs : Solubilizer in powder form, used in directly compressible dosage forms, Wet granulation, added during lubrication stage

    Ingredient(s) : Magnesium aluminium silicate Excipient, Polysorbate 80

    Dosage Form : Tablet, Capsule

    Grade : Oral

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    Ingredient(s) : Magnesium aluminium silicate Excipient, Polysorbate 80

    Dosage Form : Tablet, Capsule

    Category : API Stability Enhancers, Direct Compression, Solubilizers

    Brand : SEPITRAP 80

    Applications : Polysorbate 80 in dry powder form, a solubilizing agent acts as a surfactant and increases the solubility of various oral dosage forms.

    Pharmacopoeia Ref : USP-NF, EP, JP & having US DMF

    Technical Specs : Solubilizer in powder form, used in directly compressible dosage forms, Wet granulation, added during lubrication stage

    Grade : Oral

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