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    Looking for Direct Compression? Find Direct Compression Agents used in Promethazine Hydrochloride to address drug delivery challenges on PharmaCompass.

    EUROAPI, the leading small molecules API player, provides both API sales & CDMO services.

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    SPI Pharma has been solving formulation challenges using superior functional materials.

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    Interquim comes from an international group of 50 companies active in the pharma, hospital, diagnostics, fine chemicals & feed sectors.

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    Cohance Lifesciences, offers full range of CDMO services for small molecule APIs, intermediates, ADCs, Pellets and Formulations.

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    Promethazine Hydrochloride

    ACTIVE PHARMA INGREDIENTS

    DEVELOPMENTS

    FINISHED DOSAGE FORMULATIONS

    DRUG PRODUCT COMPOSITIONS

    RELATED EXCIPIENT COMPANIES

    EXCIPIENTS BY APPLICATIONS

    DIGITAL CONTENT

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    01 2SPI Pharma

    02 8BASF

    03 2DFE Pharma

    04 3Gangwal Chemicals

    05 5Microlex e.U

    06 3Seppic

    07 6Sigachi Industries

    08 2The Dow Chemical Company

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    01

    SPI Pharma

    U.S.A
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    Dosage Form : Tablet, Orodispersible Tablet

    Grade : Oral

    Brand Name : Compressol SM

    Application : Chewable & Orodispersible Aids, Co-Processed Excipients, Direct Compression, Fillers, Diluents & Binders, Taste Masking

    Excipient Details : Compressol® SM, co-processed polyol, is a DC excipient of mannitol & sorbitol with superior compactibility, low disintegration time & hygroscopicity.

    Pharmacopoeia Ref : NA

    Technical Specs : NA

    Ingredient(s) : Mannitol, Sorbitol

    Dosage Form : Tablet, Orodispersible Tablet

    Grade : Oral

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    Ingredient(s) : Mannitol, Sorbitol

    Dosage Form : Tablet, Orodispersible Tablet

    Category : Chewable & Orodispersible Aids, Co-Processed Excipients, Direct Compression, Fillers, Diluents & Binders, Taste Masking

    Brand : COMPRESSOL SM

    Applications : Compressol® SM, co-processed polyol, is a DC excipient of mannitol & sorbitol with superior compactibility, low disintegration time & hygroscopicity.

    Pharmacopoeia Ref : NA

    Technical Specs : NA

    Grade : Oral

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    02

    DFE Pharma

    PHARMACEL 102

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    DFE Pharma

    Germany
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    Dosage Form : Tablet

    Grade : Oral

    Brand Name : Pharmacel 102

    Application : Direct Compression

    Excipient Details : Pharmacel® 102 has good flow properties enabling high speed direct compression tableting. It is a ideal choice for direct compression & dry granulation formulations and it also has some lubrication properties for smooth tableting experience.

    Pharmacopoeia Ref : Conforms to USP-NF, Ph.Eur., J...

    Technical Specs : Density- Tapped density- 440 g/l, Bulk density- 310 g/l; Particle size- D10- 40 ?m, D50- 90 ?m, D90-180 ?m; Hausner ratio-1,42

    Ingredient(s) : Microcrystalline Cellulose

    Dosage Form : Tablet

    Grade : Oral

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    Ingredient(s) : Microcrystalline Cellulose

    Dosage Form : Tablet

    Category : Direct Compression

    Brand : PHARMACEL 102

    Applications : Pharmacel® 102 has good flow properties enabling high speed direct compression tableting. It is a ideal choice for direct compression & dry granulation formulations and it also has some lubrication properties for smooth tableting experience.

    Pharmacopoeia Ref : Conforms to USP-NF, Ph.Eur., JP, IP

    Technical Specs : Density- Tapped density- 440 g/l, Bulk density- 310 g/l; Particle size- D10- 40 ?m, D50- 90 ?m, D90-180 ?m; Hausner ratio-1,42

    Grade : Oral

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    03

    Sigachi Industries

    ACECEL

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    04

    Sigachi Industries

    HICEL

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    Not Confirmed

    05

    DFE Pharma

    SUPERTAB 21AN

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    DFE Pharma

    Germany
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    Dosage Form : Tablet

    Grade : Oral

    Brand Name : Supertab 21AN

    Application : Direct Compression

    Excipient Details : SuperTab® 11SD offers the best compactability of all grades of lactose, and it is well suited to direct compression applications. Due to the low moisture content, it is used in the formulations containing moisture sensitive drugs.

    Pharmacopoeia Ref : Conforms to Ph. Eur., Lactose ...

    Technical Specs : Density- Tapped density- 906 g/l, Bulk density- 722 g/l; Particle size- D10-15 ?m, D50- 170 ?m, D90- 340 ?m; Hausner ratio-1,25

    Ingredient(s) : Anhydrous Lactose

    Dosage Form : Tablet

    Grade : Oral

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    Ingredient(s) : Anhydrous Lactose

    Dosage Form : Tablet

    Category : Direct Compression

    Brand : SUPERTAB 21AN

    Applications : SuperTab® 11SD offers the best compactability of all grades of lactose, and it is well suited to direct compression applications. Due to the low moisture content, it is used in the formulations containing moisture sensitive drugs.

    Pharmacopoeia Ref : Conforms to Ph. Eur., Lactose monograph / USP-NF, JP Anhydrous lactose monograph

    Technical Specs : Density- Tapped density- 906 g/l, Bulk density- 722 g/l; Particle size- D10-15 ?m, D50- 170 ?m, D90- 340 ?m; Hausner ratio-1,25

    Grade : Oral

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    06

    Sigachi Industries

    HICEL HFE

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    Sigachi Industries

    India
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    Dosage Form : Orodispersible Tablet

    Grade : Oral

    Brand Name : HiCel HFE

    Application : Direct Compression, Disintegrants & Superdisintegrants

    Excipient Details : HiCel HFE has various advantages such as Improved flow, Superior compactibility, low sensitivity to lubrication, better disintegration properties. It is used in direct compression of chewable tablets, fast dissolving tablets & mouth feel enhance...

    Pharmacopoeia Ref :

    Technical Specs :

    Ingredient(s) : Mannitol, Microcrystalline Cellulose

    Dosage Form : Orodispersible Tablet

    Grade : Oral

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    Ingredient(s) : Mannitol, Microcrystalline Cellulose

    Dosage Form : Orodispersible Tablet

    Category : Direct Compression, Disintegrants & Superdisintegrants

    Brand : HICEL HFE

    Applications : HiCel HFE has various advantages such as Improved flow, Superior compactibility, low sensitivity to lubrication, better disintegration properties. It is used in direct compression of chewable tablets, fast dissolving tablets & mouth feel enhancement.

    Pharmacopoeia Ref : Not Available

    Technical Specs : Not Available

    Grade : Oral

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    07

    The Dow Chemical Company

    METHOCEL™

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    The Dow Chemical Company

    U.S.A
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    Dosage Form : Tablet, Capsule

    Grade :

    Brand Name : METHOCEL™

    Application : API Stability Enhancers, Coating Systems & Additives, Controlled & Modified Release, Direct Compression, Granulation, Rheology Modifiers, Vegetarian Capsules

    Excipient Details : Controlled Release, Direct Compression,Wet Granulation,Tablet Coating, Liquid Solutions and Suspensions

    Pharmacopoeia Ref :

    Technical Specs :

    Ingredient(s) : Hydroxypropyl Methylcellulose

    Dosage Form : Tablet, Capsule

    Grade :

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    Ingredient(s) : Hydroxypropyl Methylcellulose

    Dosage Form : Tablet, Capsule

    Category : API Stability Enhancers, Coating Systems & Additives, Controlled & Modified Release, Direct Compression, Granulation, Rheology Modifiers, Vegetarian Capsules

    Brand : METHOCEL™

    Applications : Controlled Release, Direct Compression,Wet Granulation,Tablet Coating, Liquid Solutions and Suspensions

    Pharmacopoeia Ref : Not Available

    Technical Specs : Not Available

    Grade : Not Available

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    08

    Sigachi Industries

    HICELLAC

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    Sigachi Industries

    India
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    Dosage Form : Tablet

    Grade : Oral

    Brand Name : HiCellac

    Application : Direct Compression, Granulation

    Excipient Details : HiCellac 100 is used in direct compression, dry granulation & capsule filling, suitable for low dose formulations where API content uniformity is critical. It also provides excellent compaction properties & tablet hardness.

    Pharmacopoeia Ref :

    Technical Specs :

    Ingredient(s) : Lactose Monohydrate, Microcrystalline Cellulose

    Dosage Form : Tablet

    Grade : Oral

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    Ingredient(s) : Lactose Monohydrate, Microcrystalline Cellulose

    Dosage Form : Tablet

    Category : Direct Compression, Granulation

    Brand : HICELLAC

    Applications : HiCellac 100 is used in direct compression, dry granulation & capsule filling, suitable for low dose formulations where API content uniformity is critical. It also provides excellent compaction properties & tablet hardness.

    Pharmacopoeia Ref : Not Available

    Technical Specs : Not Available

    Grade : Oral

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    09

    Sigachi Industries

    HICEL SMCC

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    10

    Microlex e.U

    MICROLEX® MCC 101

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    11

    Microlex e.U

    MICROLEX® MCC 102

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    Microlex e.U

    Austria
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    Dosage Form : Tablet

    Grade : Oral

    Brand Name : Microlex® MCC 102

    Application : Direct Compression

    Excipient Details : The plastic defamation characteristics of  MCC 102 type mean that very hard tablets can be produced at light compaction forces, extending tooling lifetime and solving problems with poorly compressible actives.

    Pharmacopoeia Ref : Monograph- USP/NF, JP/JPE

    Technical Specs :

    Ingredient(s) : Microcrystalline Cellulose

    Dosage Form : Tablet

    Grade : Oral

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    Ingredient(s) : Microcrystalline Cellulose

    Dosage Form : Tablet

    Category : Direct Compression

    Brand : MICROLEX® MCC 102

    Applications : The plastic defamation characteristics of  MCC 102 type mean that very hard tablets can be produced at light compaction forces, extending tooling lifetime and solving problems with poorly compressible actives.

    Pharmacopoeia Ref : Monograph- USP/NF, JP/JPE

    Technical Specs : Not Available

    Grade : Oral

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    Microlex e.U

    MICROLEX® LCM 80.M

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    Microlex e.U

    Austria
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    Dosage Form : Tablet

    Grade : Oral

    Brand Name : Microlex® LCM 80.m

    Application : Direct Compression, Granulation

    Excipient Details : Lactose monohydrate is typically used for wet or dry granulation. During wet granulation, liquid binders or adhesives are added to the lactose and active mixture, usually by blending.

    Pharmacopoeia Ref : Monograph- USP/NF, JP/JPE

    Technical Specs : Milled; Also Available as Microlex® LCM 180.m, Microlex® LCM 200.m

    Ingredient(s) : Lactose Monohydrate

    Dosage Form : Tablet

    Grade : Oral

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    Ingredient(s) : Lactose Monohydrate

    Dosage Form : Tablet

    Category : Direct Compression, Granulation

    Brand : MICROLEX® LCM 80.M

    Applications : Lactose monohydrate is typically used for wet or dry granulation. During wet granulation, liquid binders or adhesives are added to the lactose and active mixture, usually by blending.

    Pharmacopoeia Ref : Monograph- USP/NF, JP/JPE

    Technical Specs : Milled; Also Available as Microlex® LCM 180.m, Microlex® LCM 200.m

    Grade : Oral

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    13

    Microlex e.U

    MICROLEX® LCM 120.S

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    Austria
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    Dosage Form : Tablet

    Grade : Oral

    Brand Name : Microlex® LCM 120.s

    Application : Direct Compression, Granulation

    Excipient Details : It is also suitable for both wet granulation and direct compression methods of tablet production. Microlex® crystalline grades are used in wet granulation and the spray dried forms are used in direct compression.

    Pharmacopoeia Ref : Monograph- USP/NF, JP/JPE

    Technical Specs : Sieved; Also Available as Microlex® LCM 180.s, Microlex® LCM 220.s

    Ingredient(s) : Lactose Monohydrate

    Dosage Form : Tablet

    Grade : Oral

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    Ingredient(s) : Lactose Monohydrate

    Dosage Form : Tablet

    Category : Direct Compression, Granulation

    Brand : MICROLEX® LCM 120.S

    Applications : It is also suitable for both wet granulation and direct compression methods of tablet production. Microlex® crystalline grades are used in wet granulation and the spray dried forms are used in direct compression.

    Pharmacopoeia Ref : Monograph- USP/NF, JP/JPE

    Technical Specs : Sieved; Also Available as Microlex® LCM 180.s, Microlex® LCM 220.s

    Grade : Oral

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    Microlex e.U

    MICROLEX® LCA 60.M

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    Microlex e.U

    Austria
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    Dosage Form : Tablet

    Grade : Oral

    Brand Name : Microlex® LCA 60.m

    Application : Direct Compression, Granulation

    Excipient Details : It is also suitable for both wet granulation and direct compression methods of tablet production. Microlex® crystalline grades are used in wet granulation and the spray dried forms are used in direct compression.

    Pharmacopoeia Ref : Monograph- USP/NF, JP/JPE

    Technical Specs : Milled; Also Available as Microlex® LCA 120.m, Microlex® LCA 200.m

    Ingredient(s) : Anhydrous Lactose

    Dosage Form : Tablet

    Grade : Oral

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    Ingredient(s) : Anhydrous Lactose

    Dosage Form : Tablet

    Category : Direct Compression, Granulation

    Brand : MICROLEX® LCA 60.M

    Applications : It is also suitable for both wet granulation and direct compression methods of tablet production. Microlex® crystalline grades are used in wet granulation and the spray dried forms are used in direct compression.

    Pharmacopoeia Ref : Monograph- USP/NF, JP/JPE

    Technical Specs : Milled; Also Available as Microlex® LCA 120.m, Microlex® LCA 200.m

    Grade : Oral

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    Sigachi Industries

    FILLERLAC

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    16

    BASF

    KOLLIWAX S FINE

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    BASF

    Germany
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    Dosage Form : Capsule, Granule / Pellet, Suppository, Tablet

    Grade :

    Brand Name : Kolliwax S Fine

    Application : Direct Compression, Granulation, Lubricants & Glidants

    Excipient Details : Lipophilic lubricant, especially for sensitive acidic APIs. Matrix forming agent in sustained-release dosage forms, emulsifying and solubilizing agent in topical formulations and hardening agent in glycerin suppositories

    Pharmacopoeia Ref :

    Technical Specs :

    Ingredient(s) : Palmitic Acid, Stearic Acid

    Dosage Form : Capsule, Granule / Pellet, Suppository, Tablet

    Grade :

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    Ingredient(s) : Palmitic Acid, Stearic Acid

    Dosage Form : Capsule, Granule / Pellet, Suppository, Tablet

    Category : Direct Compression, Granulation, Lubricants & Glidants

    Brand : KOLLIWAX S FINE

    Applications : Lipophilic lubricant, especially for sensitive acidic APIs. Matrix forming agent in sustained-release dosage forms, emulsifying and solubilizing agent in topical formulations and hardening agent in glycerin suppositories

    Pharmacopoeia Ref : Not Available

    Technical Specs : Not Available

    Grade : Not Available

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    BASF

    LUDIPRESS

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    18

    BASF

    LUDIPRESS LCE

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    Not Confirmed

    19

    Seppic

    SEPITRAP 80

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    Not Confirmed

    20

    Gangwal Chemicals

    FUJICALIN SG

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    Not Confirmed

    21

    Gangwal Chemicals

    SEPITRAP 80

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    Not Confirmed

    Gangwal Chemicals

    India
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    Dosage Form : Tablet, Capsule

    Grade : Oral

    Brand Name : SEPITRAP 80

    Application : API Stability Enhancers, Direct Compression, Solubilizers

    Excipient Details : Polysorbate 80 in dry powder form, a solubilizing agent acts as a surfactant and increases the solubility of various oral dosage forms.

    Pharmacopoeia Ref : USP-NF, EP, JP & having US DMF

    Technical Specs : Solubilizer in powder form, used in directly compressible dosage forms, Wet granulation, added during lubrication stage

    Ingredient(s) : Magnesium aluminium silicate Excipient, Polysorbate 80

    Dosage Form : Tablet, Capsule

    Grade : Oral

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    Ingredient(s) : Magnesium aluminium silicate Excipient, Polysorbate 80

    Dosage Form : Tablet, Capsule

    Category : API Stability Enhancers, Direct Compression, Solubilizers

    Brand : SEPITRAP 80

    Applications : Polysorbate 80 in dry powder form, a solubilizing agent acts as a surfactant and increases the solubility of various oral dosage forms.

    Pharmacopoeia Ref : USP-NF, EP, JP & having US DMF

    Technical Specs : Solubilizer in powder form, used in directly compressible dosage forms, Wet granulation, added during lubrication stage

    Grade : Oral

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