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    Looking for Direct Compression? Find Direct Compression Agents used in Velpatasvir to address drug delivery challenges on PharmaCompass.

    EUROAPI, the leading small molecules API player, provides both API sales & CDMO services.

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    SPI Pharma has been solving formulation challenges using superior functional materials.

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    Interquim comes from an international group of 50 companies active in the pharma, hospital, diagnostics, fine chemicals & feed sectors.

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    Cohance Lifesciences, offers full range of CDMO services for small molecule APIs, intermediates, ADCs, Pellets and Formulations.

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    Velpatasvir

    ACTIVE PHARMA INGREDIENTS

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    01 2Boai NKY Pharmaceuticals Ltd

    02 7BASF

    03 1DFE Pharma

    04 4Microlex e.U

    05 1Prachin Chemical

    06 6Sigachi Industries

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    01

    Boai NKY Pharmaceuticals Ltd

    China
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    Virtual BoothBoai NKY Pharmaceuticals Ltd. is one of the largest global PVP suppliers.

    Dosage Form : Tablet

    Grade : Oral (Pharma Grade)

    Brand Name : KoVidone® VA64

    Application : Direct Compression, Fillers, Diluents & Binders, Film Formers & Plasticizers

    Excipient Details : KoVidone® VA64 is used as a binder in tablets, direct compression binder, matrix formers in amorphous solid dispersions, and film-forming polymer.

    Pharmacopoeia Ref : USP/NF, EP, JP, KP, IP, BP

    Technical Specs : NA

    Ingredient(s) : Polyvinylpyrrolidone and Vinyl Acetate Copolymer

    Dosage Form : Tablet

    Grade : Oral (Pharma Grade)

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    Virtual BoothBoai NKY Pharmaceuticals Ltd. is one of the largest global PVP suppliers.

    Ingredient(s) : Polyvinylpyrrolidone and Vinyl Acetate Copolymer

    Dosage Form : Tablet

    Category : Direct Compression, Fillers, Diluents & Binders, Film Formers & Plasticizers

    Brand : KOVIDONE® VA64

    Applications : KoVidone® VA64 is used as a binder in tablets, direct compression binder, matrix formers in amorphous solid dispersions, and film-forming polymer.

    Pharmacopoeia Ref : USP/NF, EP, JP, KP, IP, BP

    Technical Specs : NA

    Grade : Oral (Pharma Grade)

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    KoVidone® VA64

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    02

    Boai NKY Pharmaceuticals Ltd

    China
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    Virtual BoothBoai NKY Pharmaceuticals Ltd. is one of the largest global PVP suppliers.

    Dosage Form : Tablet

    Grade : Oral (Pharma Grade)

    Brand Name : KoVidone® Ultra VA64

    Application : Direct Compression, Fillers, Diluents & Binders, Film Formers & Plasticizers

    Excipient Details : KoVidone® Ultra VA64 is used as a tablet binder, direct compression binder, matrix former in amorphous solid dispersions, and film-forming polymer.

    Pharmacopoeia Ref : USP/NF, EP, JP, KP, IP, BP

    Technical Specs : NA

    Ingredient(s) : Polyvinylpyrrolidone and Vinyl Acetate Copolymer

    Dosage Form : Tablet

    Grade : Oral (Pharma Grade)

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    Virtual BoothBoai NKY Pharmaceuticals Ltd. is one of the largest global PVP suppliers.

    Ingredient(s) : Polyvinylpyrrolidone and Vinyl Acetate Copolymer

    Dosage Form : Tablet

    Category : Direct Compression, Fillers, Diluents & Binders, Film Formers & Plasticizers

    Brand : KOVIDONE® ULTRA VA64

    Applications : KoVidone® Ultra VA64 is used as a tablet binder, direct compression binder, matrix former in amorphous solid dispersions, and film-forming polymer.

    Pharmacopoeia Ref : USP/NF, EP, JP, KP, IP, BP

    Technical Specs : NA

    Grade : Oral (Pharma Grade)

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    03

    DFE Pharma

    PHARMACEL 102

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    DFE Pharma

    Germany
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    Dosage Form : Tablet

    Grade : Oral

    Brand Name : Pharmacel 102

    Application : Direct Compression

    Excipient Details : Pharmacel® 102 has good flow properties enabling high speed direct compression tableting. It is a ideal choice for direct compression & dry granulation formulations and it also has some lubrication properties for smooth tableting experience.

    Pharmacopoeia Ref : Conforms to USP-NF, Ph.Eur., J...

    Technical Specs : Density- Tapped density- 440 g/l, Bulk density- 310 g/l; Particle size- D10- 40 ?m, D50- 90 ?m, D90-180 ?m; Hausner ratio-1,42

    Ingredient(s) : Microcrystalline Cellulose

    Dosage Form : Tablet

    Grade : Oral

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    Ingredient(s) : Microcrystalline Cellulose

    Dosage Form : Tablet

    Category : Direct Compression

    Brand : PHARMACEL 102

    Applications : Pharmacel® 102 has good flow properties enabling high speed direct compression tableting. It is a ideal choice for direct compression & dry granulation formulations and it also has some lubrication properties for smooth tableting experience.

    Pharmacopoeia Ref : Conforms to USP-NF, Ph.Eur., JP, IP

    Technical Specs : Density- Tapped density- 440 g/l, Bulk density- 310 g/l; Particle size- D10- 40 ?m, D50- 90 ?m, D90-180 ?m; Hausner ratio-1,42

    Grade : Oral

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    04

    Prachin Chemical

    PARCROS

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    05

    Sigachi Industries

    ACECEL

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    06

    Sigachi Industries

    HICEL

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    07

    Sigachi Industries

    HICEL HFE

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    Not Confirmed

    Sigachi Industries

    India
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    Dosage Form : Orodispersible Tablet

    Grade : Oral

    Brand Name : HiCel HFE

    Application : Direct Compression, Disintegrants & Superdisintegrants

    Excipient Details : HiCel HFE has various advantages such as Improved flow, Superior compactibility, low sensitivity to lubrication, better disintegration properties. It is used in direct compression of chewable tablets, fast dissolving tablets & mouth feel enhance...

    Pharmacopoeia Ref :

    Technical Specs :

    Ingredient(s) : Mannitol, Microcrystalline Cellulose

    Dosage Form : Orodispersible Tablet

    Grade : Oral

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    Ingredient(s) : Mannitol, Microcrystalline Cellulose

    Dosage Form : Orodispersible Tablet

    Category : Direct Compression, Disintegrants & Superdisintegrants

    Brand : HICEL HFE

    Applications : HiCel HFE has various advantages such as Improved flow, Superior compactibility, low sensitivity to lubrication, better disintegration properties. It is used in direct compression of chewable tablets, fast dissolving tablets & mouth feel enhancement.

    Pharmacopoeia Ref : Not Available

    Technical Specs : Not Available

    Grade : Oral

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    08

    Sigachi Industries

    HICELLAC

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    Sigachi Industries

    India
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    Dosage Form : Tablet

    Grade : Oral

    Brand Name : HiCellac

    Application : Direct Compression, Granulation

    Excipient Details : HiCellac 100 is used in direct compression, dry granulation & capsule filling, suitable for low dose formulations where API content uniformity is critical. It also provides excellent compaction properties & tablet hardness.

    Pharmacopoeia Ref :

    Technical Specs :

    Ingredient(s) : Lactose Monohydrate, Microcrystalline Cellulose

    Dosage Form : Tablet

    Grade : Oral

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    Ingredient(s) : Lactose Monohydrate, Microcrystalline Cellulose

    Dosage Form : Tablet

    Category : Direct Compression, Granulation

    Brand : HICELLAC

    Applications : HiCellac 100 is used in direct compression, dry granulation & capsule filling, suitable for low dose formulations where API content uniformity is critical. It also provides excellent compaction properties & tablet hardness.

    Pharmacopoeia Ref : Not Available

    Technical Specs : Not Available

    Grade : Oral

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    09

    Sigachi Industries

    HICEL SMCC

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    10

    Microlex e.U

    MICROLEX® MCC 101

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    11

    Microlex e.U

    MICROLEX® MCC 102

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    Microlex e.U

    Austria
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    Dosage Form : Tablet

    Grade : Oral

    Brand Name : Microlex® MCC 102

    Application : Direct Compression

    Excipient Details : The plastic defamation characteristics of  MCC 102 type mean that very hard tablets can be produced at light compaction forces, extending tooling lifetime and solving problems with poorly compressible actives.

    Pharmacopoeia Ref : Monograph- USP/NF, JP/JPE

    Technical Specs :

    Ingredient(s) : Microcrystalline Cellulose

    Dosage Form : Tablet

    Grade : Oral

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    Ingredient(s) : Microcrystalline Cellulose

    Dosage Form : Tablet

    Category : Direct Compression

    Brand : MICROLEX® MCC 102

    Applications : The plastic defamation characteristics of  MCC 102 type mean that very hard tablets can be produced at light compaction forces, extending tooling lifetime and solving problems with poorly compressible actives.

    Pharmacopoeia Ref : Monograph- USP/NF, JP/JPE

    Technical Specs : Not Available

    Grade : Oral

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    12

    Microlex e.U

    MICROLEX® LCM 80.M

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    Microlex e.U

    Austria
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    Dosage Form : Tablet

    Grade : Oral

    Brand Name : Microlex® LCM 80.m

    Application : Direct Compression, Granulation

    Excipient Details : Lactose monohydrate is typically used for wet or dry granulation. During wet granulation, liquid binders or adhesives are added to the lactose and active mixture, usually by blending.

    Pharmacopoeia Ref : Monograph- USP/NF, JP/JPE

    Technical Specs : Milled; Also Available as Microlex® LCM 180.m, Microlex® LCM 200.m

    Ingredient(s) : Lactose Monohydrate

    Dosage Form : Tablet

    Grade : Oral

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    Ingredient(s) : Lactose Monohydrate

    Dosage Form : Tablet

    Category : Direct Compression, Granulation

    Brand : MICROLEX® LCM 80.M

    Applications : Lactose monohydrate is typically used for wet or dry granulation. During wet granulation, liquid binders or adhesives are added to the lactose and active mixture, usually by blending.

    Pharmacopoeia Ref : Monograph- USP/NF, JP/JPE

    Technical Specs : Milled; Also Available as Microlex® LCM 180.m, Microlex® LCM 200.m

    Grade : Oral

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    13

    Microlex e.U

    MICROLEX® LCM 120.S

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    Microlex e.U

    Austria
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    Dosage Form : Tablet

    Grade : Oral

    Brand Name : Microlex® LCM 120.s

    Application : Direct Compression, Granulation

    Excipient Details : It is also suitable for both wet granulation and direct compression methods of tablet production. Microlex® crystalline grades are used in wet granulation and the spray dried forms are used in direct compression.

    Pharmacopoeia Ref : Monograph- USP/NF, JP/JPE

    Technical Specs : Sieved; Also Available as Microlex® LCM 180.s, Microlex® LCM 220.s

    Ingredient(s) : Lactose Monohydrate

    Dosage Form : Tablet

    Grade : Oral

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    Ingredient(s) : Lactose Monohydrate

    Dosage Form : Tablet

    Category : Direct Compression, Granulation

    Brand : MICROLEX® LCM 120.S

    Applications : It is also suitable for both wet granulation and direct compression methods of tablet production. Microlex® crystalline grades are used in wet granulation and the spray dried forms are used in direct compression.

    Pharmacopoeia Ref : Monograph- USP/NF, JP/JPE

    Technical Specs : Sieved; Also Available as Microlex® LCM 180.s, Microlex® LCM 220.s

    Grade : Oral

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    14

    Sigachi Industries

    FILLERLAC

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    Not Confirmed

    15

    BASF

    KOLLIDON VA64 FINE

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    Not Confirmed

    16

    BASF

    KOLLIDON VA64

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    BASF

    Germany
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    Dosage Form : Capsule, Granule / Pellet, Softgel Capsule, Tablet

    Grade :

    Brand Name : Kollidon VA64

    Application : Direct Compression, Fillers, Diluents & Binders, Granulation

    Excipient Details : Dry binder in tablets, capsules and granules, as a film-forming agent in tablet coatings and subcoatings, and as a film-forming agent in topical sprays. Widely used in HME processes.

    Pharmacopoeia Ref : Ph. Eur., USP monograph "Copov...

    Technical Specs :

    Ingredient(s) : Vinylpyrrolidone-Vinyl Acetate

    Dosage Form : Capsule, Granule / Pellet, Softgel Capsule, Tablet

    Grade :

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    Ingredient(s) : Vinylpyrrolidone-Vinyl Acetate

    Dosage Form : Capsule, Granule / Pellet, Softgel Capsule, Tablet

    Category : Direct Compression, Fillers, Diluents & Binders, Granulation

    Brand : KOLLIDON VA64

    Applications : Dry binder in tablets, capsules and granules, as a film-forming agent in tablet coatings and subcoatings, and as a film-forming agent in topical sprays. Widely used in HME processes.

    Pharmacopoeia Ref : Ph. Eur., USP monograph "Copovidone" and the JPE monograph "Copolyvidone"

    Technical Specs : Not Available

    Grade : Not Available

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