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    Looking for Direct Compression? Find Direct Compression Agents used in Vortioxetine Hydrobromide to address drug delivery challenges on PharmaCompass.

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    SPI Pharma

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    PHARMABURST 500

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    Applications:

    Pharmaburst® 500 is a directly compressible pharmaceutical excipient used to create orally disintegrating tablets quickly and easily.

    Ingredient(s): Mannitol

    Dosage Form: Orodispersible Tablet, Tablet

    Category: Chewable & Orodispersible Aids, Direct Compression, Fillers, Diluents & Binders, Taste Masking

    Route of Administration (Grade): Oral
    Pharmacopoeia Reference: NA

    Technical Specifications: NA

    Pharmaburst 500

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    Gangwal Healthcare

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      DICOM-DC® SP204

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      Applications:

      DiCOM-DC SP204 is used as a stabilizer, filler, binder, directly compressible, and co-processed excipient in tablets and capsules.

      Ingredient(s): Corn Starch, Pregelatinized, Magnesium Oxide Excipient, Microcrystalline Cellulose, Sodium Starch Glycolate

      Dosage Form: Capsule, Tablet

      Category: Co-Processed Excipients, Direct Compression, Fillers, Diluents & Binders, Thickeners and Stabilizers

      Route of Administration (Grade): Oral
      Pharmacopoeia Reference: In-house

      Technical Specifications: NA

      Gangwal Healthcare DiCOM-DC® SP204

      ACS Fall 2024

      Not Confirmed

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      SPI Pharma

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      ADVANTOL 300

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      Applications:

      Advantol® 300 is a DC pharmaceutical excipient used to create soft chewable or soft melt oral dosage forms & enables rapid product development.

      Ingredient(s): Mannitol

      Dosage Form: Orodispersible Tablet, Tablet

      Category: Chewable & Orodispersible Aids, Direct Compression, Fillers, Diluents & Binders, Taste Masking

      Route of Administration (Grade): Oral
      Pharmacopoeia Reference: NA

      Technical Specifications: NA

      Advantol 300

      CPhI Worldwide, Milan

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      SPI Pharma

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      COMPRESSOL SM

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      Applications:

      Compressol® SM, co-processed polyol, is a DC excipient of mannitol & sorbitol with superior compactibility, lower disintegration time & hygroscopicity

      Ingredient(s): Mannitol, Sorbitol

      Dosage Form: Tablet, Orodispersible Tablet

      Category: Chewable & Orodispersible Aids, Co-Processed Excipients, Direct Compression, Fillers, Diluents & Binders, Taste Masking

      Route of Administration (Grade): Oral
      Pharmacopoeia Reference: NA

      Technical Specifications: NA

      Compressol SM

      CPhI Worldwide, Milan

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      SPI Pharma

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      MANNOGEM EZ SPRAY-DRIED

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      Applications:

      Mannogem EZ Spray-Dried, a mannitol product, dissolves rapidly and can increase the rate of tablet disintegration, drug dissolution & drug release.

      Ingredient(s): Mannitol

      Dosage Form: Orodispersible Tablet, Tablet

      Category: Chewable & Orodispersible Aids, Direct Compression, Fillers, Diluents & Binders

      Route of Administration (Grade): Oral
      Pharmacopoeia Reference: NA

      Technical Specifications: NA

      Mannogem EZ Spray-Dried

      CPhI Worldwide, Milan

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      SPI Pharma

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      MANNOGEM GRANULAR

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      Applications:

      Mannogem Granular (mannitol) dissolves rapidly and can increase the rate of tablet disintegration, subsequent drug dissolution and drug release.

      Ingredient(s): Mannitol

      Dosage Form: Orodispersible Tablet, Tablet

      Category: Chewable & Orodispersible Aids, Direct Compression, Fillers, Diluents & Binders

      Route of Administration (Grade): Oral
      Pharmacopoeia Reference: NA

      Technical Specifications: NA

      Mannogem Granular

      CPhI Worldwide, Milan

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      SPI Pharma

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      MANNOGEM® XL OPAL

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      Applications:

      Mannogem® XL Opal, directly compressible 160 µm spray-dried mannitol provides superior binding properties and tabletability.

      Ingredient(s): Mannitol

      Dosage Form: Tablet

      Category: Direct Compression, Fillers, Diluents & Binders, Taste Masking

      Route of Administration (Grade): Oral
      Pharmacopoeia Reference: NA

      Technical Specifications: 160 µm Powder Mannitol

      SPI Pharma Mannogem® XL Opal

      CPhI Worldwide, Milan

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      Gangwal Healthcare

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        DICOM-DC® SR300

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        Applications:

        DiCOM-DC SR300 is used as a directly compressible, rate-controlling, and co-processed excipient in sustained-release tablets and capsules.

        Ingredient(s): EthylCellulose, Hydroxypropyl Cellulose, Hydroxypropyl Methylcellulose, Magnesium Stearate, Maize Starch, Microcrystalline Cellulose, Silicon Dioxide, Talc

        Dosage Form: Capsule, Tablet

        Category: Co-Processed Excipients, Controlled & Modified Release, Direct Compression

        Route of Administration (Grade): Oral
        Pharmacopoeia Reference: In-house

        Technical Specifications: NA

        Gangwal Healthcare DiCOM-DC® SR300

        ACS Fall 2024

        Not Confirmed

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        Gangwal Healthcare

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          SOLVOSTAR™

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          Applications:

          Solvostar (Sodium Starch Glycolate) is used as a superdisintegrant and directly compressible excipient in tablets, capsules, suspensions, and pellets.

          Ingredient(s): Sodium Starch Glycolate

          Dosage Form: Capsule, Granule / Pellet, Tablet

          Category: Direct Compression, Disintegrants & Superdisintegrants

          Route of Administration (Grade): Oral
          Pharmacopoeia Reference: IP/BP/EP/USP-NF

          Technical Specifications: Solvostar 2% to 8%

          Gangwal Healthcare Solvostar™

          ACS Fall 2024

          Not Confirmed

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          Gangwal Healthcare

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            PROBLEND®

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            Applications:

            ProBlend (Microcrystalline Cellulose) is used as a filler, binder, glidant, DC & co-processed excipient in tablets, capsules, and MUPS formulations.

            Ingredient(s): Microcrystalline Cellulose

            Dosage Form: Capsule, Tablet

            Category: Co-Processed Excipients, Direct Compression, Disintegrants & Superdisintegrants, Fillers, Diluents & Binders, Lubricants & Glidants

            Route of Administration (Grade): Oral
            Pharmacopoeia Reference: USP-NF

            Technical Specifications: NA

            Gangwal Healthcare ProBlend®

            ACS Fall 2024

            Not Confirmed

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            Gangwal Healthcare

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              MICROLOSE™ M60 P60

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              Applications:

              Microlose M60 P60 is used as a filler, binder, directly compressible, and co-processed excipient in tablets and capsules.

              Ingredient(s): Lactose Monohydrate, Microcrystalline Cellulose

              Dosage Form: Capsule, Tablet

              Category: Co-Processed Excipients, Direct Compression, Fillers, Diluents & Binders

              Route of Administration (Grade): Oral
              Pharmacopoeia Reference: In-house

              Technical Specifications: Lactose Monohydrate – 40%, Microcrystalline cellulose – 60%

              Gangwal Healthcare Microlose™ M60 P60

              ACS Fall 2024

              Not Confirmed

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              Gangwal Healthcare

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                DICOM-DC® PL009 P60

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                Applications:

                DiCOM-DC PL009 P60 is used as a filler, binder, directly compressible, and co-processed excipient in tablets and capsules.

                Ingredient(s): Maize Starch, Microcrystalline Cellulose

                Dosage Form: Capsule, Tablet

                Category: Co-Processed Excipients, Direct Compression, Fillers, Diluents & Binders

                Route of Administration (Grade): Oral
                Pharmacopoeia Reference: IH

                Technical Specifications: NA

                Gangwal Healthcare DiCOM-DC® PL009 P60

                ACS Fall 2024

                Not Confirmed

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                DFE Pharma

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                PHARMACEL 102

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                Applications:

                Pharmacel® 102 has good flow properties enabling high speed direct compression tableting. It is a ideal choice for direct compression & dry granulation formulations and it also has some lubrication properties for smooth tableting experience.

                Ingredient(s): Microcrystalline Cellulose

                Dosage Form: Tablet

                Category: Direct Compression

                Route of Administration (Grade): Oral
                Pharmacopoeia Reference: Conforms to USP-NF, Ph.Eur., JP, IP

                Technical Specifications: Density- Tapped density- 440 g/l, Bulk density- 310 g/l; Particle size- D10- 40 ?m, D50- 90 ?m, D90-180 ?m; Hausner ratio-1,42

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                Sigachi Industries

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                  ACECEL

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                  Applications:

                  AceCel is suitable for majority of the directly compressible actives, combines good flow and high compressibility.

                  Ingredient(s): Microcrystalline Cellulose

                  Dosage Form: Tablet

                  Category: Direct Compression, Fillers, Diluents & Binders, Granulation

                  Route of Administration (Grade): Oral
                  Pharmacopoeia Reference: Not Available

                  Technical Specifications: Not Available
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                  Sigachi Industries

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                    HICEL

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                    Applications:

                    HiCel acts as a strong & dry binder. It facilitates low tablet friability & promotes rapid tablet disintegration.

                    Ingredient(s): Microcrystalline Cellulose

                    Dosage Form: Tablet

                    Category: Direct Compression, Fillers, Diluents & Binders, Granulation

                    Route of Administration (Grade): Oral
                    Pharmacopoeia Reference: Not Available

                    Technical Specifications: Not Available
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                    Sigachi Industries

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                      HICEL HFE

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                      Applications:

                      HiCel HFE has various advantages such as Improved flow, Superior compactibility, low sensitivity to lubrication, better disintegration properties. It is used in direct compression of chewable tablets, fast dissolving tablets & mouth feel enhancement.

                      Ingredient(s): Mannitol, Microcrystalline Cellulose

                      Dosage Form: Orodispersible Tablet

                      Category: Direct Compression, Disintegrants & Superdisintegrants

                      Route of Administration (Grade): Oral
                      Pharmacopoeia Reference: Not Available

                      Technical Specifications: Not Available
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                      Sigachi Industries

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                        HICELLAC

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                        Applications:

                        HiCellac 100 is used in direct compression, dry granulation & capsule filling, suitable for low dose formulations where API content uniformity is critical. It also provides excellent compaction properties & tablet hardness.

                        Ingredient(s): Lactose Monohydrate, Microcrystalline Cellulose

                        Dosage Form: Tablet

                        Category: Direct Compression, Granulation

                        Route of Administration (Grade): Oral
                        Pharmacopoeia Reference: Not Available

                        Technical Specifications: Not Available
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                        Sigachi Industries

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                          HICEL SMCC

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                          Applications:

                          HiCel SMCC has unique combination which result in optimum compaction & superior flow properties.

                          Ingredient(s): Microcrystalline Cellulose, Silicon Dioxide

                          Dosage Form: Tablet

                          Category: Direct Compression, Fillers, Diluents & Binders, Lubricants & Glidants

                          Route of Administration (Grade): Oral
                          Pharmacopoeia Reference: Not Available

                          Technical Specifications: Not Available
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                          Microlex e.U

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                            MICROLEX® MCC 101

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                            Applications:

                            Tablets made from these granules are typically easily disintegrated using conventional super disintegrates even when hard tablets are compressed.

                            Ingredient(s): Microcrystalline Cellulose

                            Dosage Form: Tablet

                            Category: Direct Compression, Granulation

                            Route of Administration (Grade): Oral
                            Pharmacopoeia Reference: Monograph- USP/NF, JP/JPE

                            Technical Specifications: Not Available
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                            Microlex e.U

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                              MICROLEX® MCC 102

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                              Applications:

                              The plastic defamation characteristics of  MCC 102 type mean that very hard tablets can be produced at light compaction forces, extending tooling lifetime and solving problems with poorly compressible actives.

                              Ingredient(s): Microcrystalline Cellulose

                              Dosage Form: Tablet

                              Category: Direct Compression

                              Route of Administration (Grade): Oral
                              Pharmacopoeia Reference: Monograph- USP/NF, JP/JPE

                              Technical Specifications: Not Available
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                              Microlex e.U

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                                MICROLEX® MLP 520

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                                Applications:

                                Use in a wide range of oral applications such as wet or dry granulation, excipient of choice for flash release forms.

                                Ingredient(s): Mannitol

                                Dosage Form: Capsule, Tablet

                                Category: Direct Compression, Fillers, Diluents & Binders, Granulation

                                Route of Administration (Grade): Topical, Oral
                                Pharmacopoeia Reference: Monograph- Ph.Eur, USP/NF

                                Technical Specifications: Available in different particle size as 25.µ, 50.µ, 180.µ
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                                BASF

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                                LUDIFLASH

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                                Applications:

                                Ludiflash is a ready-to-use orally disintegrating tablet (ODT) solution with superior mouthfeel.

                                Ingredient(s): Crospovidone, Mannitol, Polyvinyl Acetate

                                Dosage Form: Orodispersible Tablet

                                Category: Chewable & Orodispersible Aids, Direct Compression, Granulation

                                Route of Administration (Grade): Not Available
                                Pharmacopoeia Reference: Ph. Eur., USP, JP: 90 % mannitol, 5 % crospovidone, 5 % polyvinyl acetate

                                Technical Specifications: Not Available
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