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    Looking for Granulation? Find Granulation Agents used in Tapentadol to address drug delivery challenges on PharmaCompass.

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    Tapentadol

    ACTIVE PHARMA INGREDIENTS

    DEVELOPMENTS

    INTERMEDIATES

    FINISHED DOSAGE FORMULATIONS

    DRUG PRODUCT COMPOSITIONS

    RELATED EXCIPIENT COMPANIES

    EXCIPIENTS BY APPLICATIONS

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    01 20BASF

    02 2DFE Pharma

    03 1Kima Chemical

    04 3Microlex e.U

    05 2Pharmatrans-Sanaq

    06 1Prachin Chemical

    07 4Sigachi Industries

    08 2The Dow Chemical Company

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    PharmaCompass

    01

    BASF

    KOLLIDON SR

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    BASF

    Germany
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    Dosage Form : Capsule, Tablet, Topical Film, Transdermal Patch

    Grade :

    Brand Name : Kollidon SR

    Application : Controlled & Modified Release, Direct Compression, Granulation

    Excipient Details : For non-erodible matrices using direct compression, Controlled release matrix. Matrix former in transdermal patches and topical films.

    Pharmacopoeia Ref : Ph. Eur., USP-NF, JP-JPE: 80 %...

    Technical Specs :

    Ingredient(s) : Hydrated Silica, Lauryl Sulfate, Polyvinyl Acetate, Povidone

    Dosage Form : Capsule, Tablet, Topical Film, Transdermal Patch

    Grade :

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    Ingredient(s) : Hydrated Silica, Lauryl Sulfate, Polyvinyl Acetate, Povidone

    Dosage Form : Capsule, Tablet, Topical Film, Transdermal Patch

    Category : Controlled & Modified Release, Direct Compression, Granulation

    Brand : KOLLIDON SR

    Applications : For non-erodible matrices using direct compression, Controlled release matrix. Matrix former in transdermal patches and topical films.

    Pharmacopoeia Ref : Ph. Eur., USP-NF, JP-JPE: 80 % Polyvinyl acetate and 19 % povidone, 0.8 % lauryl sulfate & 0.2 % silica (4:1)

    Technical Specs : Not Available

    Grade : Not Available

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    02

    Prachin Chemical

    PARCROS

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    03

    Sigachi Industries

    ACECEL

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    Not Confirmed

    04

    Sigachi Industries

    HICEL

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    Not Confirmed

    05

    DFE Pharma

    PHARMATOSE 200M

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    DFE Pharma

    Germany
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    Dosage Form : Capsule, Tablet

    Grade : Oral

    Brand Name : Pharmatose 200M

    Application : Fillers, Diluents & Binders, Granulation

    Excipient Details : Pharmatose® 200M is a pharmaceutical excipient that is a highly consistent monohydrate lactose which delivers good compaction properties. This lactose type is typically used in oral dosage forms like tablets and pharmaceutical capsules.

    Pharmacopoeia Ref : Conforms to USP-NF, Ph.Eur., J...

    Technical Specs : Density- Tapped density- 857 g/l, Bulk density- 589 g/l; Particle size- D10- 5 ?m, D50- 40 ?m, D90- 120 ?m; Hausner ratio- 1,46

    Ingredient(s) : Lactose Monohydrate

    Dosage Form : Capsule, Tablet

    Grade : Oral

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    Ingredient(s) : Lactose Monohydrate

    Dosage Form : Capsule, Tablet

    Category : Fillers, Diluents & Binders, Granulation

    Brand : PHARMATOSE 200M

    Applications : Pharmatose® 200M is a pharmaceutical excipient that is a highly consistent monohydrate lactose which delivers good compaction properties. This lactose type is typically used in oral dosage forms like tablets and pharmaceutical capsules.

    Pharmacopoeia Ref : Conforms to USP-NF, Ph.Eur., JP lactose monohydrate monograph

    Technical Specs : Density- Tapped density- 857 g/l, Bulk density- 589 g/l; Particle size- D10- 5 ?m, D50- 40 ?m, D90- 120 ?m; Hausner ratio- 1,46

    Grade : Oral

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    06

    Pharmatrans-Sanaq

    MCC SANAQ

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    Pharmatrans-Sanaq

    Switzerland
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    Dosage Form : Capsule, Tablet

    Grade : Oral

    Brand Name : MCC SANAQ

    Application : Fillers, Diluents & Binders, Granulation

    Excipient Details : Microcrystalline Cellulose is mainly used as filling, binding and blasting material for tablets (direct tableting), as well as for dry and wet granulation and as filling material for hard gelatin capsules.

    Pharmacopoeia Ref : EP./USP.NF

    Technical Specs : NA

    Ingredient(s) : Microcrystalline Cellulose

    Dosage Form : Capsule, Tablet

    Grade : Oral

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    Ingredient(s) : Microcrystalline Cellulose

    Dosage Form : Capsule, Tablet

    Category : Fillers, Diluents & Binders, Granulation

    Brand : MCC SANAQ

    Applications : Microcrystalline Cellulose is mainly used as filling, binding and blasting material for tablets (direct tableting), as well as for dry and wet granulation and as filling material for hard gelatin capsules.

    Pharmacopoeia Ref : EP./USP.NF

    Technical Specs : NA

    Grade : Oral

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    07

    The Dow Chemical Company

    METHOCEL™

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    The Dow Chemical Company

    U.S.A
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    Dosage Form : Tablet, Capsule

    Grade :

    Brand Name : METHOCEL™

    Application : API Stability Enhancers, Coating Systems & Additives, Controlled & Modified Release, Direct Compression, Granulation, Rheology Modifiers, Vegetarian Capsules

    Excipient Details : Controlled Release, Direct Compression,Wet Granulation,Tablet Coating, Liquid Solutions and Suspensions

    Pharmacopoeia Ref :

    Technical Specs :

    Ingredient(s) : Hydroxypropyl Methylcellulose

    Dosage Form : Tablet, Capsule

    Grade :

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    Ingredient(s) : Hydroxypropyl Methylcellulose

    Dosage Form : Tablet, Capsule

    Category : API Stability Enhancers, Coating Systems & Additives, Controlled & Modified Release, Direct Compression, Granulation, Rheology Modifiers, Vegetarian Capsules

    Brand : METHOCEL™

    Applications : Controlled Release, Direct Compression,Wet Granulation,Tablet Coating, Liquid Solutions and Suspensions

    Pharmacopoeia Ref : Not Available

    Technical Specs : Not Available

    Grade : Not Available

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    08

    Kima Chemical

    HYDROXYPROPYL METHYL CELLULOSE (60E3)

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    09

    Sigachi Industries

    HILOSE

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    Sigachi Industries

    India
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    Dosage Form : Tablet

    Grade : Oral

    Brand Name : Hilose

    Application : Disintegrants & Superdisintegrants, Granulation

    Excipient Details : It is used in oral pharmaceutical formulations as a super disintegrant for Capsules, Tablets & Granules Formulations. In tablet formulations, it is used in both direct compression & wet granulation processes.

    Pharmacopoeia Ref :

    Technical Specs :

    Ingredient(s) : Croscarmellose Sodium

    Dosage Form : Tablet

    Grade : Oral

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    Ingredient(s) : Croscarmellose Sodium

    Dosage Form : Tablet

    Category : Disintegrants & Superdisintegrants, Granulation

    Brand : HILOSE

    Applications : It is used in oral pharmaceutical formulations as a super disintegrant for Capsules, Tablets & Granules Formulations. In tablet formulations, it is used in both direct compression & wet granulation processes.

    Pharmacopoeia Ref : Not Available

    Technical Specs : Not Available

    Grade : Oral

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    10

    Sigachi Industries

    HICELLAC

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    Sigachi Industries

    India
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    Dosage Form : Tablet

    Grade : Oral

    Brand Name : HiCellac

    Application : Direct Compression, Granulation

    Excipient Details : HiCellac 100 is used in direct compression, dry granulation & capsule filling, suitable for low dose formulations where API content uniformity is critical. It also provides excellent compaction properties & tablet hardness.

    Pharmacopoeia Ref :

    Technical Specs :

    Ingredient(s) : Lactose Monohydrate, Microcrystalline Cellulose

    Dosage Form : Tablet

    Grade : Oral

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    Ingredient(s) : Lactose Monohydrate, Microcrystalline Cellulose

    Dosage Form : Tablet

    Category : Direct Compression, Granulation

    Brand : HICELLAC

    Applications : HiCellac 100 is used in direct compression, dry granulation & capsule filling, suitable for low dose formulations where API content uniformity is critical. It also provides excellent compaction properties & tablet hardness.

    Pharmacopoeia Ref : Not Available

    Technical Specs : Not Available

    Grade : Oral

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    11

    Microlex e.U

    MICROLEX® MCC 101

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    12

    Microlex e.U

    MICROLEX® LCM 80.M

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    Microlex e.U

    Austria
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    Dosage Form : Tablet

    Grade : Oral

    Brand Name : Microlex® LCM 80.m

    Application : Direct Compression, Granulation

    Excipient Details : Lactose monohydrate is typically used for wet or dry granulation. During wet granulation, liquid binders or adhesives are added to the lactose and active mixture, usually by blending.

    Pharmacopoeia Ref : Monograph- USP/NF, JP/JPE

    Technical Specs : Milled; Also Available as Microlex® LCM 180.m, Microlex® LCM 200.m

    Ingredient(s) : Lactose Monohydrate

    Dosage Form : Tablet

    Grade : Oral

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    Ingredient(s) : Lactose Monohydrate

    Dosage Form : Tablet

    Category : Direct Compression, Granulation

    Brand : MICROLEX® LCM 80.M

    Applications : Lactose monohydrate is typically used for wet or dry granulation. During wet granulation, liquid binders or adhesives are added to the lactose and active mixture, usually by blending.

    Pharmacopoeia Ref : Monograph- USP/NF, JP/JPE

    Technical Specs : Milled; Also Available as Microlex® LCM 180.m, Microlex® LCM 200.m

    Grade : Oral

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    13

    Microlex e.U

    MICROLEX® LCM 120.S

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    Microlex e.U

    Austria
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    Dosage Form : Tablet

    Grade : Oral

    Brand Name : Microlex® LCM 120.s

    Application : Direct Compression, Granulation

    Excipient Details : It is also suitable for both wet granulation and direct compression methods of tablet production. Microlex® crystalline grades are used in wet granulation and the spray dried forms are used in direct compression.

    Pharmacopoeia Ref : Monograph- USP/NF, JP/JPE

    Technical Specs : Sieved; Also Available as Microlex® LCM 180.s, Microlex® LCM 220.s

    Ingredient(s) : Lactose Monohydrate

    Dosage Form : Tablet

    Grade : Oral

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    Ingredient(s) : Lactose Monohydrate

    Dosage Form : Tablet

    Category : Direct Compression, Granulation

    Brand : MICROLEX® LCM 120.S

    Applications : It is also suitable for both wet granulation and direct compression methods of tablet production. Microlex® crystalline grades are used in wet granulation and the spray dried forms are used in direct compression.

    Pharmacopoeia Ref : Monograph- USP/NF, JP/JPE

    Technical Specs : Sieved; Also Available as Microlex® LCM 180.s, Microlex® LCM 220.s

    Grade : Oral

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    14

    BASF

    LUDIPRESS

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    15

    BASF

    LUDIPRESS LCE

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    16

    BASF

    KOLLIDON 30 LP

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    17

    BASF

    KOLLIDON 90 F

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    BASF

    Germany
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    Dosage Form : Capsule, Granule / Pellet, Softgel Capsule, Suspension, Tablet

    Grade :

    Brand Name : Kollidon 90 F

    Application : Fillers, Diluents & Binders, Granulation, Solubilizers

    Excipient Details : Tablet binding, thickener, stabilizers of suspensions, reduces sedimentation, crystallization inhibition.

    Pharmacopoeia Ref : Ph. Eur., USP, JP: Povidone

    Technical Specs :

    Ingredient(s) : Povidone

    Dosage Form : Capsule, Granule / Pellet, Softgel Capsule, Suspension, Tablet

    Grade :

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    Ingredient(s) : Povidone

    Dosage Form : Capsule, Granule / Pellet, Softgel Capsule, Suspension, Tablet

    Category : Fillers, Diluents & Binders, Granulation, Solubilizers

    Brand : KOLLIDON 90 F

    Applications : Tablet binding, thickener, stabilizers of suspensions, reduces sedimentation, crystallization inhibition.

    Pharmacopoeia Ref : Ph. Eur., USP, JP: Povidone

    Technical Specs : Not Available

    Grade : Not Available

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    18

    BASF

    SOLUPLUS

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    BASF

    Germany
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    Dosage Form : Solution, Tablet, Topical Film, Transdermal Patch

    Grade :

    Brand Name : Soluplus

    Application : Controlled & Modified Release, Granulation, Solubilizers

    Excipient Details : Solubility and bioavailability enhancement, ideal for hot melt extrusion (HME)

    Pharmacopoeia Ref : Polyvinyl caprolactam – poly...

    Technical Specs :

    Ingredient(s) : polyethylene glycol, Polyvinyl Acetate

    Dosage Form : Solution, Tablet, Topical Film, Transdermal Patch

    Grade :

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    Ingredient(s) : polyethylene glycol, Polyvinyl Acetate

    Dosage Form : Solution, Tablet, Topical Film, Transdermal Patch

    Category : Controlled & Modified Release, Granulation, Solubilizers

    Brand : SOLUPLUS

    Applications : Solubility and bioavailability enhancement, ideal for hot melt extrusion (HME)

    Pharmacopoeia Ref : Polyvinyl caprolactam – polyvinyl acetate – polyethylene glycol graft copolymer

    Technical Specs : Not Available

    Grade : Not Available

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