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    Looking for Solubilizers? Find Solubilizers Agents used in Tacrolimus to address drug delivery challenges on PharmaCompass.

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    Boai NKY Pharmaceuticals Ltd. is one of the largest global PVP suppliers.
    SPI Pharma has been solving formulation challenges using superior functional materials.
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    01 SPI Pharma (3)

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    03 Nanjing Well Pharmaceutical (11)

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    SPI Pharma

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    TAP®

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    Applications:

    TAP® pellets are spherical cores made of tartaric acid used for solubility enhancement of drugs exhibiting poor solubility in alkali environments.

    Ingredient(s): Tartaric Acid

    Dosage Form: Capsule, Granule / Pellet, Tablet

    Category: Solubilizers

    Route of Administration (Grade): Oral
    Pharmacopoeia Reference: NA

    Technical Specifications: Bulk density: 0.8-1.1

    TAP

    CPhI Worldwide, Milan

    Booth #6G33

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    DKSH

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    SYNTADEX 7702

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    Applications:

    Syntadex 7702 is used as a solubilizer in ophthalmic drug products and in topical formulations such as creams, lotions, and ointments.

    Ingredient(s): Petroleum Jelly Excipient

    Dosage Form: Cream / Lotion / Ointment, Ophthalmic Solution

    Category: Solubilizers, Topical

    Route of Administration (Grade): Topical, Parenteral
    Pharmacopoeia Reference: N/A

    Technical Specifications: N/A

    SYNTADEX 7702

    CPhI Worldwide, Milan

    Booth #6C42

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    Nanjing Well Pharmaceutical

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      POLOXAMER 188

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      Applications:

      Poloxamer 188 is used as a solubilizer and wetting agent in oral dosage forms such as tablets and topical formulations such as creams, gels, lotions, and ointments. It is also used as a coating plasticizer for oral solids.

      Ingredient(s): Poloxamer 188

      Dosage Form: Cream / Lotion / Ointment, Gel, Injectable / Parenteral, Tablet

      Category: Parenteral, Solubilizers, Topical

      Route of Administration (Grade): Parenteral, Oral, Topical
      Pharmacopoeia Reference: ChP/USP/EP

      Technical Specifications: NA

      Nanjing Well Poloxamer 188

      IPS 2024

      Not Confirmed

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      Nanjing Well Pharmaceutical

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        POLYOXYL 60 HYDROGENATED CASTOR OIL

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        Applications:

        Polyoxyl (60) hydrogenated castor oil is used as a wetting agent in oral dosage forms such as tablets. It is also used in SEDDS and as a solubilizer in topical dosage forms such as creams, lotions, ointments, and gels.

        Ingredient(s): Polyoxyl 60 Hydrogenated Castor Oil

        Dosage Form: Cream / Lotion / Ointment, Gel, Tablet

        Category: Solubilizers, Topical

        Route of Administration (Grade): Oral, Topical
        Pharmacopoeia Reference: ChP/USP/EP

        Technical Specifications: NA

        Polyoxyl 60 Hydrogenated Castor Oil

        IPS 2024

        Not Confirmed

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        Nanjing Well Pharmaceutical

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          PROPYLENE CARBONATE

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          Applications:

          Propylene carbonate is used in oral dosage forms such as tablets, and in topical dosage forms such as creams, lotions, ointments, and gels. It is also used as a solvent in parenteral dosage forms.

          Ingredient(s): Propylene Carbonate

          Dosage Form: Cream / Lotion / Ointment, Gel, Injectable / Parenteral, Tablet

          Category: Parenteral, Solubilizers, Topical

          Route of Administration (Grade): Parenteral, Oral, Topical
          Pharmacopoeia Reference: ChP/USP

          Technical Specifications: NA

          Nanjing Well Propylene Carbonate

          IPS 2024

          Not Confirmed

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          Valens Pharmachem

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            HYDROSOL 50

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            Applications:

            Hydrosol 50 is used as a solubilizer and emulsifying agent in oral and topical liquid and semi-solid dosage forms.

            Ingredient(s): Polyoxyl 40 Hydrogenated Castor Oil, Propylene Glycol

            Dosage Form: Cream / Lotion / Ointment, Gel, Solution

            Category: Emulsifying Agents, Solubilizers, Topical

            Route of Administration (Grade): Oral, Topical
            Pharmacopoeia Reference: USP/NF

            Technical Specifications: N/A
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            The Dow Chemical Company

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            AFFINISOL HPMC HME

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            Applications:

            Solubility enhancement, Spray-Dried Dispersion (SDD), Hot Melt Extrusion (HME)

            Ingredient(s): Hydroxypropyl Methylcellulose

            Dosage Form: Tablet

            Category: Solubilizers

            Route of Administration (Grade): Not Available
            Pharmacopoeia Reference: Not Available

            Technical Specifications: Not Available
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            Nanjing Bold Chemical

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              POLOXAMER 188

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              Applications:

              Poloxamer 188 provides better storage stability. It is used as solubilizers for liquid preparation & oral care products, matrix materials for ointment & gel.

              Ingredient(s): Poloxamer 188

              Dosage Form: Cream / Lotion / Ointment, Granule / Pellet, Tablet

              Category: Solubilizers, Thickeners and Stabilizers

              Route of Administration (Grade): Oral & Parenteral
              Pharmacopoeia Reference: Not Available

              Technical Specifications: Not Available
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              BASF

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              KOLLISOLV PG

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              Applications:

              Liquid plasticizer with high ADI, hydrophilic solvent & humectant in emulsions, skin penetration enhancer in topical formulaitons.

              Ingredient(s): Propylene Glycol

              Dosage Form: Capsule, Emulsion, Softgel Capsule, Solution, Tablet, Topical Film

              Category: Film Formers & Plasticizers, Solubilizers, Topical

              Route of Administration (Grade): Not Available
              Pharmacopoeia Reference: Ph. Eur., JP, FCC, USP

              Technical Specifications: Not Available
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              Corel Pharma Chem

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                ACRYSOL K-160

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                Applications:

                Solubilizer, dissolution improver, emulsifier, masking agent, moisturizer, aerosol formulations.

                Ingredient(s): Polyoxyl 60 Hydrogenated Castor Oil

                Dosage Form: Dry Syrup, Emulsion, Nasal Solution, Solution, Suspension, Syrup

                Category: Emulsifying Agents, Solubilizers, Taste Masking

                Route of Administration (Grade): Not Available
                Pharmacopoeia Reference: Not Available

                Technical Specifications: Not Available
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