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    Looking for Solubilizers? Find Solubilizers Agents used in Tapentadol to address drug delivery challenges on PharmaCompass.

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    Tapentadol

    ACTIVE PHARMA INGREDIENTS

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    01 42BASF

    02 2Gangwal Chemicals

    03 1Microlex e.U

    04 1The Dow Chemical Company

    05 3Valens Pharmachem

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    01

    Valens Pharmachem

    HYDROSOL 50

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    Valens Pharmachem

    India
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    Dosage Form : Cream / Lotion / Ointment, Gel, Solution

    Grade : Oral, Topical

    Brand Name : HYDROSOL 50

    Application : Emulsifying Agents, Solubilizers, Topical

    Excipient Details : Hydrosol 50 is used as a solubilizer and emulsifying agent in oral and topical liquid and semi-solid dosage forms.

    Pharmacopoeia Ref : USP/NF

    Technical Specs : N/A

    Ingredient(s) : Polyoxyl 40 Hydrogenated Castor Oil, Propylene Glycol

    Dosage Form : Cream / Lotion / Ointment, Gel, Solution

    Grade : Oral, Topical

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    Ingredient(s) : Polyoxyl 40 Hydrogenated Castor Oil, Propylene Glycol

    Dosage Form : Cream / Lotion / Ointment, Gel, Solution

    Category : Emulsifying Agents, Solubilizers, Topical

    Brand : HYDROSOL 50

    Applications : Hydrosol 50 is used as a solubilizer and emulsifying agent in oral and topical liquid and semi-solid dosage forms.

    Pharmacopoeia Ref : USP/NF

    Technical Specs : N/A

    Grade : Oral, Topical

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    02

    The Dow Chemical Company

    AFFINISOL HPMC HME

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    03

    Microlex e.U

    MICROLEX® PVD K30

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    Microlex e.U

    Austria
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    Dosage Form : Tablet

    Grade : Oral

    Brand Name : Microlex® PVD K30

    Application : Solubilizers

    Excipient Details : It is among the most commonly used solid dispersion carrires to solubilize poorly soluble drugs, It can stabilize amorphous drugs in polymer dispersions and maintain supersaturation of API, aqueous solutions by preventing precipitation/cryst...

    Pharmacopoeia Ref : Monograph- USP/NF, JP/JPE

    Technical Specs : Also Available as Microlex® PVD K90.

    Ingredient(s) : Povidone

    Dosage Form : Tablet

    Grade : Oral

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    Ingredient(s) : Povidone

    Dosage Form : Tablet

    Category : Solubilizers

    Brand : MICROLEX® PVD K30

    Applications : It is among the most commonly used solid dispersion carrires to solubilize poorly soluble drugs, It can stabilize amorphous drugs in polymer dispersions and maintain supersaturation of API, aqueous solutions by preventing precipitation/crystallization

    Pharmacopoeia Ref : Monograph- USP/NF, JP/JPE

    Technical Specs : Also Available as Microlex® PVD K90.

    Grade : Oral

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    04

    BASF

    KOLLISOLV PG

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    Not Confirmed

    BASF

    Germany
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    Dosage Form : Capsule, Emulsion, Softgel Capsule, Solution, Tablet, Topical Film

    Grade :

    Brand Name : Kollisolv PG

    Application : Film Formers & Plasticizers, Solubilizers, Topical

    Excipient Details : Liquid plasticizer with high ADI, hydrophilic solvent & humectant in emulsions, skin penetration enhancer in topical formulaitons.

    Pharmacopoeia Ref : Ph. Eur., JP, FCC, USP

    Technical Specs :

    Ingredient(s) : Propylene Glycol

    Dosage Form : Capsule, Emulsion, Softgel Capsule, Solution, Tablet, Topical Film

    Grade :

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    Ingredient(s) : Propylene Glycol

    Dosage Form : Capsule, Emulsion, Softgel Capsule, Solution, Tablet, Topical Film

    Category : Film Formers & Plasticizers, Solubilizers, Topical

    Brand : KOLLISOLV PG

    Applications : Liquid plasticizer with high ADI, hydrophilic solvent & humectant in emulsions, skin penetration enhancer in topical formulaitons.

    Pharmacopoeia Ref : Ph. Eur., JP, FCC, USP

    Technical Specs : Not Available

    Grade : Not Available

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    05

    Gangwal Chemicals

    KOVIDONE-K

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    Gangwal Chemicals

    India
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    Dosage Form : Capsule, Tablet

    Grade : Oral

    Brand Name : KOVIDONE-K

    Application : Coating Systems & Additives, Fillers, Diluents & Binders, Film Formers & Plasticizers, Solubilizers, Thickeners and Stabilizers

    Excipient Details : Kovidone- K series products posses excellent binding, film-forming, dispersing, and thickning properties and are widely used in the following dosage forms. Binder, Solubilizer, Coating agent, Suspending, Stabilizing or viscocity modifying agent

    Pharmacopoeia Ref : USP-NF, EP, BP, IP, JP, FCC

    Technical Specs : PVP K-K-30/ K-17/ K19/ K25/ K90

    Ingredient(s) : Crospovidone, Povidone

    Dosage Form : Capsule, Tablet

    Grade : Oral

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    Ingredient(s) : Crospovidone, Povidone

    Dosage Form : Capsule, Tablet

    Category : Coating Systems & Additives, Fillers, Diluents & Binders, Film Formers & Plasticizers, Solubilizers, Thickeners and Stabilizers

    Brand : KOVIDONE-K

    Applications : Kovidone- K series products posses excellent binding, film-forming, dispersing, and thickning properties and are widely used in the following dosage forms. Binder, Solubilizer, Coating agent, Suspending, Stabilizing or viscocity modifying agent

    Pharmacopoeia Ref : USP-NF, EP, BP, IP, JP, FCC

    Technical Specs : PVP K-K-30/ K-17/ K19/ K25/ K90

    Grade : Oral

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    06

    BASF

    KOLLIDON 30

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    Not Confirmed

    07

    BASF

    KOLLISOLV PEG 400

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    Not Confirmed

    08

    BASF

    KOLLIDON 90 F

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    Not Confirmed

    BASF

    Germany
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    Not Confirmed
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    Dosage Form : Capsule, Granule / Pellet, Softgel Capsule, Suspension, Tablet

    Grade :

    Brand Name : Kollidon 90 F

    Application : Fillers, Diluents & Binders, Granulation, Solubilizers

    Excipient Details : Tablet binding, thickener, stabilizers of suspensions, reduces sedimentation, crystallization inhibition.

    Pharmacopoeia Ref : Ph. Eur., USP, JP: Povidone

    Technical Specs :

    Ingredient(s) : Povidone

    Dosage Form : Capsule, Granule / Pellet, Softgel Capsule, Suspension, Tablet

    Grade :

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    Ingredient(s) : Povidone

    Dosage Form : Capsule, Granule / Pellet, Softgel Capsule, Suspension, Tablet

    Category : Fillers, Diluents & Binders, Granulation, Solubilizers

    Brand : KOLLIDON 90 F

    Applications : Tablet binding, thickener, stabilizers of suspensions, reduces sedimentation, crystallization inhibition.

    Pharmacopoeia Ref : Ph. Eur., USP, JP: Povidone

    Technical Specs : Not Available

    Grade : Not Available

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    09

    BASF

    SOLUPLUS

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    BASF

    Germany
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    Dosage Form : Solution, Tablet, Topical Film, Transdermal Patch

    Grade :

    Brand Name : Soluplus

    Application : Controlled & Modified Release, Granulation, Solubilizers

    Excipient Details : Solubility and bioavailability enhancement, ideal for hot melt extrusion (HME)

    Pharmacopoeia Ref : Polyvinyl caprolactam – poly...

    Technical Specs :

    Ingredient(s) : polyethylene glycol, Polyvinyl Acetate

    Dosage Form : Solution, Tablet, Topical Film, Transdermal Patch

    Grade :

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    Ingredient(s) : polyethylene glycol, Polyvinyl Acetate

    Dosage Form : Solution, Tablet, Topical Film, Transdermal Patch

    Category : Controlled & Modified Release, Granulation, Solubilizers

    Brand : SOLUPLUS

    Applications : Solubility and bioavailability enhancement, ideal for hot melt extrusion (HME)

    Pharmacopoeia Ref : Polyvinyl caprolactam – polyvinyl acetate – polyethylene glycol graft copolymer

    Technical Specs : Not Available

    Grade : Not Available

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    10

    BASF

    KOLLISOLV PEG 300

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    Not Confirmed

    11

    BASF

    KOLLIDON 17 PF

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    Not Confirmed

    12

    BASF

    KOLLIDON 12 PF

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    Not Confirmed

    13

    BASF

    KOLLISOLV PEG 600

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    Not Confirmed