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Assessing the physicochemimal properties of drug compounds are typical early steps in drug discovery. A good compound has high enough water solubility to be able to dissolve to blood/plasma and other aqueous bodily fluids, whilst also having certain amount of lipophilicity to permeate across biological membranes, like the intestine wall (especially important for compounds aimed for oral dosing). Lipophilicity is possibly the lost important physicochemical property of a potential drug, it plays a