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    AcuraStem Enters into a License Agreement with Takeda to Advance PIKFYVE Therapeutics

    Details:

    Under the terms of the agreement, Takeda will receive an exclusive, worldwide license to AcuraStem's PIKFYVE targeted therapeutics including AS-202, an innovative antisense oligonucleotide (ASO) for the treatment of Amyotrophic Lateral Sclerosis (ALS).


    Lead Product(s): AS-202

    Therapeutic Area: Neurology Product Name: AS-202

    Highest Development Status: IND EnablingProduct Type: Large molecule

    Partner/Sponsor/Collaborator: Takeda Pharmaceutical

    Deal Size: $580.0 million Upfront Cash: Undisclosed

    Deal Type: Licensing Agreement September 25, 2023

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    AcuraStem Awarded $1M DOD Grant to Advance AS-202 Drug Development Candidate for ALS

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    The CDMRP award nomination underscores the significance of AcuraStem’s drug candidate AS-202. AcuraStem’s most advanced therapeutic candidate, AS-202, lowers levels of the lipid kinase PIKFYVE.


    Lead Product(s): AS-202

    Therapeutic Area: Neurology Product Name: AS-202

    Highest Development Status: IND EnablingProduct Type: Small molecule

    Partner/Sponsor/Collaborator: U.S Department of Defense

    Deal Size: $1.0 million Upfront Cash: Undisclosed

    Deal Type: Funding May 25, 2021

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