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Bionxt Solutions
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The net proceeds will be used for the development and commercialization of cladribine. It involves targeting the cells of the adaptive immune system on treating multiple sclerosis.


Lead Product(s): Cladribine

Therapeutic Area: Neurology Product Name: Cladribine-Generic

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Undisclosed

Deal Size: $1.6 million Upfront Cash: Undisclosed

Deal Type: Private Placement June 19, 2024

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The Company intends to use the net proceeds research, development, and commercialization programs, including its proprietary ODF Cladribine dosage form, directed at the multiple sclerosis.


Lead Product(s): Cladribine

Therapeutic Area: Neurology Product Name: Cladribine-Generic

Highest Development Status: Phase IProduct Type: Small molecule

Partner/Sponsor/Collaborator: Undisclosed

Deal Size: $1.6 million Upfront Cash: Undisclosed

Deal Type: Private Placement April 25, 2024

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Cladribine, an oral dissolvable film product, is incorporated into DNA strands where it inhibits DNA synthesis and repair, it is being developed for the treatment of Multiple Sclerosis.


Lead Product(s): Cladribine

Therapeutic Area: Neurology Product Name: Cladribine-Generic

Highest Development Status: PreclinicalProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable March 13, 2024

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Cladribine-Generic is a ribonucleoside-diphosphate reductase inhibitor. Its orodispersible film is being evaluated in precinical studies for the treatment of Multiple Sclerosis.


Lead Product(s): Cladribine

Therapeutic Area: Neurology Product Name: Cladribine-Generic

Highest Development Status: PreclinicalProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable March 01, 2024

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Details:

Cladribine-Generic is a ribonucleoside-diphosphate reductase inhibitor. Its orodispersible film is being evaluated in precinical studies for the treatment of Multiple Sclerosis.


Lead Product(s): Cladribine

Therapeutic Area: Neurology Product Name: Cladribine-Generic

Highest Development Status: PreclinicalProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable February 07, 2024

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The net proceeds will be used for the development and commercialization of cladribine. It involves targeting the cells of the adaptive immune system with minimal impact on innate immune cells for the treatment of multiple sclerosis (MS).


Lead Product(s): Cladribine

Therapeutic Area: Neurology Product Name: Cladribine-Generic

Highest Development Status: PreclinicalProduct Type: Small molecule

Partner/Sponsor/Collaborator: Undisclosed

Deal Size: $1.1 million Upfront Cash: Undisclosed

Deal Type: Private Placement January 29, 2024

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Cladribine based oral dissolvable drug film (ODF) reformulation is being evaluated for the treatment of Multiple Sclerosis (MS). Preclinical work is underway with comparative pharmacokinetic and local toxicity studies in animal models having already commenced in Europe.


Lead Product(s): Cladribine

Therapeutic Area: Neurology Product Name: Cladribine-Generic

Highest Development Status: PreclinicalProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable November 20, 2023

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Under the agreement, BioNxt acquires intellectual property rights and joint development of an oral dissolvable drug reformulation using the active pharmaceutical ingredient Cladribine.


Lead Product(s): Cladribine

Therapeutic Area: Neurology Product Name: Undisclosed

Highest Development Status: UndisclosedProduct Type: Small molecule

Recipient: Undisclosed

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Agreement November 13, 2023

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Details:

The Company intends to use the net proceeds from the Offering, including the Final Tranche, to fund its research, development, and commercialization activities for Rotigotine and for general working capital purposes.


Lead Product(s): Rotigotine

Therapeutic Area: Neurology Product Name: Undisclosed

Highest Development Status: PreclinicalProduct Type: Small molecule

Partner/Sponsor/Collaborator: Undisclosed

Deal Size: $2.0 million Upfront Cash: Undisclosed

Deal Type: Private Placement October 27, 2023

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The Company intends to use the net proceeds to fund its research, development, and commercialization activities of its drug canditates, including Rotigotine, a non-ergoline dopamine agonist approved for the treatment of Parkinson's disease and restless legs syndrome.


Lead Product(s): Rotigotine

Therapeutic Area: Neurology Product Name: Undisclosed

Highest Development Status: IND EnablingProduct Type: Small molecule

Partner/Sponsor/Collaborator: Undisclosed

Deal Size: $3.9 million Upfront Cash: Undisclosed

Deal Type: Private Placement September 28, 2023

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