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The collaboration aims to focus on the advancement of the clinical development of TG4050, an individualized immunotherapy being developed for solid tumors. It is being evaluated in Phase I for the treatment of Squamous Cell Carcinoma of Head and Neck.


Lead Product(s): TG4050

Therapeutic Area: Oncology Product Name: TG4050

Highest Development Status: Phase IProduct Type: Vaccine

Partner/Sponsor/Collaborator: Transgene

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Expanded Collaboration March 05, 2024

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Under the collaboration, BostonGene will support the Phase I/II study of LCB84, a TROP2-directed antibody-drug conjugate (ADC), in patients with advanced cancers.


Lead Product(s): LCB84,Anti-PD-1 Ab

Therapeutic Area: Oncology Product Name: LCB84

Highest Development Status: Phase I/ Phase IIProduct Type: Large molecule

Recipient: LegoChem Biosciences

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Collaboration November 07, 2023

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Study finds that tumor behavior specificities linked with patient responses, and the MxIF analyses identified 14 unique cellular neighborhoods in multi-region tumors that can be utilized to optimize treatment strategies for patients with ccRCC.


Lead Product(s): Undisclosed

Therapeutic Area: Oncology Product Name: Undisclosed

Highest Development Status: PreclinicalProduct Type: Undisclosed

Partner/Sponsor/Collaborator: Washington University School of Medicine

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable October 04, 2022

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Transgene’s myvac® platform brings together a series of highly innovative technologies, such as viral genome engineering, to achieve high-speed modular manufacturing of bespoke immunotherapies.


Lead Product(s): TG4050

Therapeutic Area: Oncology Product Name: TG4050

Highest Development Status: Phase IProduct Type: Vaccine

Partner/Sponsor/Collaborator: Transgene

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Collaboration October 06, 2020

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The collaboration aims to define predictors of response to PI3 kinase inhibition in relapsed/refractory T-cell lymphomas.


Lead Product(s): Duvelisib

Therapeutic Area: Oncology Product Name: Copiktra

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: The Weinstock Laboratory

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Collaboration August 04, 2020

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