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Carmell Therapeutics
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U.S.A
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2403 Sidney Street, Suite 300 Pittsburgh, PA 15203
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(412) 894-8248
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Axolotl designs, develops and sells human amnion-based allograft products for active soft tissue repair, aesthetics and orthopedic indications and is also enrolling a Phase I/II trial for Ankle Osteoarthritis and developing a topical cosmeceutical for skin rejuvenation.


Lead Product(s): Axolotl Graft

Therapeutic Area: Trauma (Emergency, Injury, Surgery) Product Name: Axolotl Graft

Highest Development Status: ApprovedProduct Type: Cell and Gene therapy

Recipient: Axolotl Biologix

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Merger September 12, 2023

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Axolotl designs, develops and sells human amnion-based allograft products for active soft tissue repair, aesthetics and orthopedic indications and is also enrolling a Phase I/II trial for Ankle Osteoarthritis and developing a topical cosmeceutical for skin rejuvenation.


Lead Product(s): Axolotl Graft

Therapeutic Area: Trauma (Emergency, Injury, Surgery) Product Name: Axolotl Graft

Highest Development Status: ApprovedProduct Type: Large molecule

Recipient: Axolotl Biologix

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Merger September 05, 2023

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Axolotl designs, develops and sells human amnion-based allograft products for active soft tissue repair, aesthetics and orthopedic indications and is also enrolling a Phase I/II trial for Ankle Osteoarthritis and developing a topical cosmeceutical for skin rejuvenation.


Lead Product(s): Axolotl Graft

Therapeutic Area: Trauma (Emergency, Injury, Surgery) Product Name: Axolotl Graft

Highest Development Status: ApprovedProduct Type: Large molecule

Recipient: Axolotl Biologix

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Merger August 09, 2023

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Axolotl designs, develops and sells human amnion-based allograft products for active soft tissue repair, aesthetics and orthopedic indications and is also enrolling a Phase I/II trial for Ankle Osteoarthritis and developing a topical cosmeceutical for skin rejuvenation.


Lead Product(s): Axolotl Graft

Therapeutic Area: Trauma (Emergency, Injury, Surgery) Product Name: Axolotl Graft

Highest Development Status: ApprovedProduct Type: Large molecule

Recipient: Axolotl Biologix

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Merger July 27, 2023

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Carmell Therapeutics is in early preclinical testing of BHA product as an orthobiolgoic to determine the capability of BHA to act as an enhancer to existing bone graft substitutes as well as a stand-alone new alternative to bone graft substitute products.


Lead Product(s): Allogeneic Plasma-based Biomaterial,Calcium Phosphate

Therapeutic Area: Orthopedics/Orthopedic Surgery Product Name: BHA

Highest Development Status: Phase IIProduct Type: Large molecule

Partner/Sponsor/Collaborator: Alpha Healthcare Acquisition Corp.

Deal Size: $154.0 million Upfront Cash: Undisclosed

Deal Type: Merger January 04, 2023

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The Fast Track status offers the company benefits in improving and accelerating the company's trial on Bone Healing Accelerant in open tibia fractures to the target of a Biologic License Application.


Lead Product(s): Calcium Phosphate,Blood-derived component

Therapeutic Area: Orthopedics/Orthopedic Surgery Product Name: Undisclosed

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable April 27, 2020

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Carmell to begin enrolling in pivotal clinical program for first-of-its-kind Plasma-based Bioactive Material product used in long-bone fractures as an adjunctive treatment.


Lead Product(s): Calcium Phosphate

Therapeutic Area: Orthopedics/Orthopedic Surgery Product Name: Undisclosed

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable January 07, 2020

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