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Concentric Analgesics
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101 California Street, Suite 1210 San Francisco, CA 94111
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415.484.7921
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The pilot study showed that vocacapsaicin, administered during surgery at a dose of 24 mg (0.3 mg/mL solution), reduced pain after coughing by 46% compared to the placebo control during the first 96 hours after surgery (p=0.02).


Lead Product(s): Vocacapsaicin

Therapeutic Area: Gastroenterology Product Name: CA-008

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable March 30, 2022

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The company has entered into a formal agreement with Evolution Research Group (ERG), a leading postsurgical pain clinical research site network in the U.S., to conduct its registration trials with CA-008 (vocacapsaicin).


Lead Product(s): Vocacapsaicin,Ketorolac Trometamol,Paracetamol

Therapeutic Area: Neurology Product Name: CA-008

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Evolution Research Group

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Agreement February 02, 2022

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URMC will participate in the vocacapsaicin Phase 3 clinical trials and develop innovative methods to capture vocacapsaicin’s benefit to patient recovery and rehabilitation.


Lead Product(s): Vocacapsaicin,Ketorolac Trometamol,Paracetamol

Therapeutic Area: Neurology Product Name: CA-008

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: University of Rochester Medical Center

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Collaboration February 02, 2022

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Concentric intends to use the proceeds from the financing to further fund Phase 3 development activities for vocacapsaicin, its lead therapeutic candidate for postsurgical pain.


Lead Product(s): Vocacapsaicin,Ketorolac Trometamol,Paracetamol

Therapeutic Area: Neurology Product Name: CA-008

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Undisclosed

Deal Size: $20.0 million Upfront Cash: Undisclosed

Deal Type: Financing January 26, 2022

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