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    Ensho Therapeutics Launches with Phase 2-Ready Oral α4β7 Inhibitor for IBD

    Details:

    Ensho has the right to develop, manufacture, and commercialize a portfolio of oral alpha-4 beta-7 integrin integrin inhibitors, EA1080 (NSHO-101), globally, excluding certain Asian jurisdictions.


    Lead Product(s): NSHO-101

    Therapeutic Area: Gastroenterology Product Name: EA1080

    Highest Development Status: Phase IProduct Type: Small molecule

    Partner/Sponsor/Collaborator: Ensho Therapeutics

    Deal Size: Undisclosed Upfront Cash: Undisclosed

    Deal Type: Licensing Agreement June 27, 2024

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    EA Pharma and Ensho Sign License Agreement for EA1080, α4β7 Integrin Antagonist

    Details:

    Under the terms of the license agreement, Ensho will conduct global clinical studies for EA1080, which is being evaluated in the early-stage clinical studies for inflammatory bowel disease.


    Lead Product(s): NSHO-101

    Therapeutic Area: Gastroenterology Product Name: EA1080

    Highest Development Status: Phase IProduct Type: Small molecule

    Partner/Sponsor/Collaborator: Ensho Therapeutics

    Deal Size: Undisclosed Upfront Cash: Undisclosed

    Deal Type: Licensing Agreement June 27, 2024

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    “MOVICOL® HD” Launched - A New Dosage Form Added to Polyethylene Glycol Chronic Constipation Treatment for the First Time in Japan

    Details:

    MOVICOL® HD is a high dose formulation of existing “MOVICOL® LD”, the first polyethylene glycol indicated for treatment of chronic constipation1) in Japan. MOVICOL® HD contains the same active ingredients in double the quantity of MOVICOL® LD per sachet.


    Lead Product(s): Macrogol

    Therapeutic Area: Gastroenterology Product Name: Movicol HD

    Highest Development Status: ApprovedProduct Type: Small molecule

    Partner/Sponsor/Collaborator: Mochida Pharmaceutical

    Deal Size: Not Applicable Upfront Cash: Not Applicable

    Deal Type: Not Applicable May 20, 2022

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    All-case Surveillance Condition for Approval of “Actonel® 17.5 mg tablets” for Treatment of Paget’s Disease of Bone Cleared in Japan

    Details:

    Actonel (risedronate sodium hydrate) tablet act as inhibits osteoclasts, which is indicated for the treatment of Paget’s disease and treatment and prevention of postmenopausal osteoporosis.


    Lead Product(s): Risedronate Sodium

    Therapeutic Area: Rare Diseases and Disorders Product Name: Actonel

    Highest Development Status: ApprovedProduct Type: Small molecule

    Partner/Sponsor/Collaborator: Eisai

    Deal Size: Not Applicable Upfront Cash: Not Applicable

    Deal Type: Not Applicable March 19, 2020

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