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Ensem Therapeutics
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U.S.A
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200 Boston Ave, Suite 1875 Medford MA 02155
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781-874-2500
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BG-68501, a small molecule cyclin-dependent kinase 2 (CDK2) inhibitor, which is being evaluated for the treatment of HR+/HER2 solid tumors including breast, ovarian, and Small Cell Lung Cancer.


Lead Product(s): BG-68501,Fulvestrant

Therapeutic Area: Oncology Product Name: BG-68501

Highest Development Status: Phase IProduct Type: Small molecule

Recipient: BeiGene

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable June 12, 2024

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Under the agreement, BeiGene will acquire an exclusive global license to an Investigational New Drug application-ready, ETX-197, an oral cyclin-dependent kinase 2 (CDK2) inhibitor.


Lead Product(s): ETX-197

Therapeutic Area: Oncology Product Name: ETX-197

Highest Development Status: IND EnablingProduct Type: Small molecule

Partner/Sponsor/Collaborator: BeiGene

Deal Size: $1,330.0 million Upfront Cash: Undisclosed

Deal Type: Licensing Agreement November 21, 2023

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Proceeds will be used to further advance the company's Kinetic Ensemble platform and accelerate R&D pipeline. Biomolecules such as proteins and RNAs are in constant motion, with an ensemble of conformations that govern their functions.


Lead Product(s): Undisclosed

Therapeutic Area: Oncology Product Name: Undisclosed

Highest Development Status: DiscoveryProduct Type: Small molecule

Partner/Sponsor/Collaborator: GGV Capital

Deal Size: $67.0 million Upfront Cash: Undisclosed

Deal Type: Series A Financing April 06, 2022

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