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Through the licensing agreement, the company will focus on advancing XVIR-110, which is currently being evaluated in early-stage clinical trials for the treatment of HIV infections.


Lead Product(s): XVIR-110

Therapeutic Area: Infections and Infectious Diseases Product Name: XVIR-110

Highest Development Status: PreclinicalProduct Type: Small molecule

Partner/Sponsor/Collaborator: ViiV Healthcare

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Licensing Agreement May 22, 2024

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The proceeds will be used to advance XVIR-110, an ultra-long-acting HIV integrase inhibitor with a preclinical profile that suggests best-in-class potential for HIV pre-exposure prophylaxis, and for HIV treatment as the cornerstone of a next-generation multi-drug regimen.


Lead Product(s): XVIR-110

Therapeutic Area: Infections and Infectious Diseases Product Name: XVIR-110

Highest Development Status: IND EnablingProduct Type: Small molecule

Partner/Sponsor/Collaborator: National Institute of Allergy and Infectious Diseases

Deal Size: $3.0 million Upfront Cash: Undisclosed

Deal Type: Funding August 22, 2023

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XVIR-120, a novel nano-formulated prodrug of dolutegravir, across preliminary rodent and non-human primate studies which demonstrate that injections were well tolerated and support ultra-long-acting dosing intervals.


Lead Product(s): Dolutegravir Prodrug

Therapeutic Area: Infections and Infectious Diseases Product Name: XVIR-120

Highest Development Status: PreclinicalProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable June 09, 2022

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INSTI - ULA, a once yearly ultra-long-acting (ULA) injectable agent targeting HIV integrase small molecules, currently in IND-enabling studies.


Lead Product(s): INSTI - ULA

Therapeutic Area: Infections and Infectious Diseases Product Name: INSTI - ULA

Highest Development Status: IND EnablingProduct Type: Cell and Gene therapy

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable November 10, 2021

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