Holoclara is focused on identifying molecules from worm species for safe, orally-available therapeutics. The rise in allergic and autoimmune diseases since the early 1900s coincides with the removal of gut-resident worms in industrialized nations. Areas with high gut worm infestation rates typically exhibit low incidences of these diseases, suggesting that worm-derived molecules may suppress inflammation and aid tissue repair....
Holoclara is focused on identifying molecules from worm species for safe, orally-available therapeutics. The rise in allergic and autoimmune diseases since the early 1900s coincides with the removal of gut-resident worms in industrialized nations. Areas with high gut worm infestation rates typically exhibit low incidences of these diseases, suggesting that worm-derived molecules may suppress inflammation and aid tissue repair. Holoclara aims to leverage these insights to develop innovative treatments that target the mechanisms underlying allergic and autoimmune conditions, offering new hope for effective therapeutic interventions.
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