![Renejix CDMO Partner for Small Molecule Oral Dosage Forms](https://www.pharmacompass.com/image/flap/renejix-w35-desktop-header-01gif-33629.gif)
![Renejix CDMO Partner for Small Molecule Oral Dosage Forms](https://www.pharmacompass.com/image/flap/renejix-w35-mob-header-01gif-17728.gif)
Upload your Marketing & Sales content on your company Virtual Booth, click HERE.
Details:
HB-500 is an alternating, 2-vector novel arenaviral therapeutic vaccine which is under clinical development for the treatment of human immunodeficiency virus (HIV).
Lead Product(s): HB-500
Therapeutic Area: Infections and Infectious Diseases Product Name: HB-500
Highest Development Status: Phase IProduct Type: Vaccine
Partner/Sponsor/Collaborator: Gilead Sciences
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable July 01, 2024
Details:
HB-200, in combination with pembrolizumab, will undergo evaluation as a first-line treatment for patients with HPV16+ recurrent or metastatic oropharyngeal squamous cell carcinoma.
Lead Product(s): HB-200,Pembrolizumab
Therapeutic Area: Oncology Product Name: HB-200
Highest Development Status: Phase IIProduct Type: Vaccine
Partner/Sponsor/Collaborator: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable April 25, 2024
Details:
HB-700 is a novel arenaviral therapeutic vaccine, which is being evaluated for the treatment of KRAS-mutated lung, colorectal, pancreatic and other cancers by targeting the five most prevalent KRAS mutations in these disease indications: G12D, G12V, G12R, G12C and G13D.
Lead Product(s): HB-700
Therapeutic Area: Oncology Product Name: HB-700
Highest Development Status: IND EnablingProduct Type: Vaccine
Partner/Sponsor/Collaborator: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable April 24, 2024
Details:
The financing aims to fund the HOOKIPA investigational product HB-500, which is a 2-vector arenaviral therapeutic vaccine. It is currently under evaluation as a component of a potential curative regimen for HIV infections.
Lead Product(s): HB-500
Therapeutic Area: Infections and Infectious Diseases Product Name: HB-500
Highest Development Status: IND EnablingProduct Type: Vaccine
Partner/Sponsor/Collaborator: Gilead Sciences
Deal Size: $21.2 million Upfront Cash: Undisclosed
Deal Type: Financing December 21, 2023
Details:
HB-500 is an alternating, 2-vector novel arenaviral therapeutic vaccine which is under clinical development for the treatment of human immunodeficiency virus (HIV).
Lead Product(s): HB-500
Therapeutic Area: Infections and Infectious Diseases Product Name: HB-500
Highest Development Status: IND EnablingProduct Type: Vaccine
Partner/Sponsor/Collaborator: Gilead Sciences
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable November 20, 2023
Details:
HB-200 is HOOKIPA’s lead oncology candidate engineered with the its proprietary replicating arenaviral vector platform. HB-200 in combination with pembrolizumab received Fast Track Designation for the treatment of 1st-line recurrent/metastatic HPV16+ head and neck cancers.
Lead Product(s): HB-200,Pembrolizumab
Therapeutic Area: Oncology Product Name: HB-200
Highest Development Status: Phase IIProduct Type: Vaccine
Partner/Sponsor/Collaborator: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable May 31, 2023
Details:
HB-400 (GS-2829) is an alternating, 2-vector non-replicating arenaviral therapeutic vaccine which uses the lymphocytic choriomeningitis virus and pichinde virus as arenaviral backbones,for the treatment of chronic hepatitis B.
Lead Product(s): GS-2829,GS-6779
Therapeutic Area: Infections and Infectious Diseases Product Name: HB-400
Highest Development Status: Phase IProduct Type: Vaccine
Partner/Sponsor/Collaborator: Gilead Sciences
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable May 09, 2023
Details:
The collaboration between HOOKIPA and Roche is to license and develop HB-700, a novel arenaviral immunotherapy for KRAS-mutated cancers and an option for a second, undisclosed arenaviral immunotherapy. HOOKIPA is conducting research through Phase 1b for HB-700.
Lead Product(s): HB-700
Therapeutic Area: Oncology Product Name: HB-700
Highest Development Status: PreclinicalProduct Type: Large molecule
Partner/Sponsor/Collaborator: F. Hoffmann-La Roche
Deal Size: $955.0 million Upfront Cash: $25.0 million
Deal Type: Collaboration February 13, 2023
Details:
Following the submission of the clinical trial application (IND equivalent) for HB-400, a Hepatitis B therapeutic, in 2022, HOOKIPA expects the first patient to be dosed in a Phase 1 clinical trial during 2023.
Lead Product(s): HB-400
Therapeutic Area: Infections and Infectious Diseases Product Name: HB-400
Highest Development Status: PreclinicalProduct Type: Vaccine
Partner/Sponsor/Collaborator: Gilead Sciences
Deal Size: $410.0 million Upfront Cash: $10.0 million
Deal Type: Collaboration January 04, 2023
Details:
HOOKIPA will conduct development, based on its proprietary arenavirus platform, through Phase 1b for HB-700, an arenaviral immunotherapy for treatment of KRAS-mutated cancers and option to license a second undisclosed novel arenaviral immunotherapy.
Lead Product(s): HB-700
Therapeutic Area: Oncology Product Name: HB-700
Highest Development Status: PreclinicalProduct Type: Large molecule
Partner/Sponsor/Collaborator: F. Hoffmann-La Roche
Deal Size: $955.0 million Upfront Cash: $25.0 million
Deal Type: Collaboration October 20, 2022