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INTERVIEW #SpeakPharma
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19 Apr 2025
// REUTERS
https://www.reuters.com/business/healthcare-pharmaceuticals/uk-approves-combination-therapies-gsks-blood-cancer-drug-blenrep-2025-04-17/
16 Apr 2025
// REUTERS
https://www.reuters.com/business/healthcare-pharmaceuticals/gsk-breach-misleading-prescribing-information-omjjara-industry-body-says-2025-04-15/
16 Apr 2025
// FIERCE PHARMA
https://www.fiercepharma.com/marketing/gsk-scolded-after-complainant-flags-shocking-error-prescribing-information
16 Apr 2025
// BUSINESSWIRE
https://www.businesswire.com/news/home/20250415426978/en/AREXVY-recommended-for-adults-aged-50-59-at-increased-risk-for-severe-respiratory-syncytial-virus-RSV-disease-by-US-Advisory-Committee-on-Immunization-Practices
09 Apr 2025
// BUSINESSWIRE
https://www.businesswire.com/news/home/20250408389277/en/GSK-Awards-%242M-in-Grant-Funding-for-Programs-Supporting-Adult-Vaccination-Commits-Additional-%242M-for-2025
08 Apr 2025
// PR NEWSWIRE
https://www.prnewswire.com/news-releases/abl-bio-announces-grabody-b-brain-delivery-platform-license-agreement-with-gsk-to-develop-novel-medicines-for-neurodegenerative-diseases-302421547.html
Details:
Blenrep (belantamab mafodotin-blmf) is an anti-BCMA ADC. It is being evaluated in combination with pomalidomide, bortezomib and dexamethasone for the treatment of relapsed/refractory multiple myeloma.
Lead Product(s): Belantamab Mafodotin,Bortezomib,Dexamethasone
Therapeutic Area: Oncology Brand Name: Blenrep
Study Phase: Approved FDFProduct Type: Antibody-drug Conjugate
Sponsor: Inapplicable
Deal Size: Inapplicable Upfront Cash: Inapplicable
Deal Type: Inapplicable April 19, 2025
Lead Product(s) : Belantamab Mafodotin,Bortezomib,Dexamethasone
Therapeutic Area : Oncology
Highest Development Status : Approved FDF
Partner/Sponsor/Collaborator : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
GSK's Blenrep Combinations Approved by UK MHRA in Relapsed/refractory Multiple Myeloma
Details : Blenrep (belantamab mafodotin-blmf) is an anti-BCMA ADC. It is being evaluated in combination with pomalidomide, bortezomib and dexamethasone for the treatment of relapsed/refractory multiple myeloma.
Product Name : Blenrep
Product Type : Antibody-drug Conjugate
Upfront Cash : Inapplicable
April 19, 2025
Details:
Under the licensing agreement, GSK will develop novel medicines for neurodegenerative diseases by utilizing ABL Bio's blood-brain barrier (BBB) shuttle platform, Grabody-B.
Lead Product(s): Undisclosed
Therapeutic Area: Neurology Brand Name: Undisclosed
Study Phase: Discovery PlatformProduct Type: Oligonucleotide
Recipient: ABL Bio
Deal Size: $101.9 million Upfront Cash: $49.6 million
Deal Type: Licensing Agreement April 06, 2025
Lead Product(s) : Undisclosed
Therapeutic Area : Neurology
Highest Development Status : Discovery Platform
Recipient : ABL Bio
Deal Size : $101.9 million
Deal Type : Licensing Agreement
ABL Bio Licenses Brain Drug Platform to GSK for Neuro Diseases
Details : Under the licensing agreement, GSK will develop novel medicines for neurodegenerative diseases by utilizing ABL Bio's blood-brain barrier (BBB) shuttle platform, Grabody-B.
Product Name : Undisclosed
Product Type : Oligonucleotide
Upfront Cash : $49.6 million
April 06, 2025
Details:
Blujepa (gepotidacin) is the first in a new class of oral antibiotics which inhibits topoisomerase II/IV. It is approved for the treatment of uncomplicated urinary tract infections.
Lead Product(s): Gepotidacin
Therapeutic Area: Infections and Infectious Diseases Brand Name: Blujepa
Study Phase: Approved FDFProduct Type: Antibiotic
Sponsor: Inapplicable
Deal Size: Inapplicable Upfront Cash: Inapplicable
Deal Type: Inapplicable March 25, 2025
Lead Product(s) : Gepotidacin
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Approved FDF
Partner/Sponsor/Collaborator : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Blujepa (Gepotidacin) FDA-Approved for Uncomplicated Urinary Tract Infections
Details : Blujepa (gepotidacin) is the first in a new class of oral antibiotics which inhibits topoisomerase II/IV. It is approved for the treatment of uncomplicated urinary tract infections.
Product Name : Blujepa
Product Type : Antibiotic
Upfront Cash : Inapplicable
March 25, 2025
Details:
Nucala (mepolizumab) is the first targeted anti-Interleukin-5 (IL-5) biologic. It is being investigated for the treament of COPD with an eosinophilic phenotype.
Lead Product(s): Mepolizumab
Therapeutic Area: Pulmonary/Respiratory Diseases Brand Name: Nucala
Study Phase: Phase IIIProduct Type: Antibody
Sponsor: Inapplicable
Deal Size: Inapplicable Upfront Cash: Inapplicable
Deal Type: Inapplicable March 24, 2025
Lead Product(s) : Mepolizumab
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase III
Partner/Sponsor/Collaborator : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
EMA Reviews GSK’s Nucala Expansion for COPD Treatment
Details : Nucala (mepolizumab) is the first targeted anti-Interleukin-5 (IL-5) biologic. It is being investigated for the treament of COPD with an eosinophilic phenotype.
Product Name : Nucala
Product Type : Antibody
Upfront Cash : Inapplicable
March 24, 2025
Details:
VH109, a CD4-binding broadly neutralising antibody, in combination with monthly cabotegravir long-acting (CAB LA), successfully kept viral levels suppressed in adults living with HIV.
Lead Product(s): VH109,Cabotegravir
Therapeutic Area: Infections and Infectious Diseases Brand Name: VH3810109
Study Phase: Phase IIProduct Type: Antibody
Sponsor: Inapplicable
Deal Size: Inapplicable Upfront Cash: Inapplicable
Deal Type: Inapplicable March 12, 2025
Lead Product(s) : VH109,Cabotegravir
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Partner/Sponsor/Collaborator : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
ViiV’s N6LS Antibody Maintains Long-Acting Viral Suppression in HIV Treatment
Details : VH109, a CD4-binding broadly neutralising antibody, in combination with monthly cabotegravir long-acting (CAB LA), successfully kept viral levels suppressed in adults living with HIV.
Product Name : VH3810109
Product Type : Antibody
Upfront Cash : Inapplicable
March 12, 2025
Details:
Penmenvy approved for use in individuals aged 10 to 25 years. The vaccine targets 5 major serogroups of Neisseria meningitidis (A, B, C, W, & Y) which commonly cause invasive meningococcal disease.
Lead Product(s): Meningococcal Groups A, B, C, W, and Y Vaccine
Therapeutic Area: Infections and Infectious Diseases Brand Name: Penmenvy
Study Phase: Approved FDFProduct Type: Vaccine
Sponsor: Inapplicable
Deal Size: Inapplicable Upfront Cash: Inapplicable
Deal Type: Inapplicable February 15, 2025
Lead Product(s) : Meningococcal Groups A, B, C, W, and Y Vaccine
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Approved FDF
Partner/Sponsor/Collaborator : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
US FDA Approves GSK's Combo Meningococcal Vaccine
Details : Penmenvy approved for use in individuals aged 10 to 25 years. The vaccine targets 5 major serogroups of Neisseria meningitidis (A, B, C, W, & Y) which commonly cause invasive meningococcal disease.
Product Name : Penmenvy
Product Type : Vaccine
Upfront Cash : Inapplicable
February 15, 2025
Details:
GSK3511294 (depemokimab) is the first ultra-long-acting biologic with a binding affinity for IL-5. It is being evaluated for the treatment of severe asthma With an eosinophilic phenotype.
Lead Product(s): Depemokimab
Therapeutic Area: Infections and Infectious Diseases Brand Name: GSK3511294
Study Phase: Phase IIIProduct Type: Antibody
Sponsor: Inapplicable
Deal Size: Inapplicable Upfront Cash: Inapplicable
Deal Type: Inapplicable January 28, 2025
Lead Product(s) : Depemokimab
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase III
Partner/Sponsor/Collaborator : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
EMA Reviews Depemokimab for Asthma with Type 2 Inflammation and CRSwNP
Details : GSK3511294 (depemokimab) is the first ultra-long-acting biologic with a binding affinity for IL-5. It is being evaluated for the treatment of severe asthma With an eosinophilic phenotype.
Product Name : GSK3511294
Product Type : Antibody
Upfront Cash : Inapplicable
January 28, 2025
Details:
Shingrix (recombinant zoster vaccine) is a non-live, recombinant subunit vaccine, being evaluated as a prefilled syringe administration for prevention of shingles in at-risk adults aged 18 and over.
Lead Product(s): Zoster Vaccine Recombinant, Adjuvanted
Therapeutic Area: Infections and Infectious Diseases Brand Name: Shingrix
Study Phase: Phase IIIProduct Type: Vaccine
Sponsor: Inapplicable
Deal Size: Inapplicable Upfront Cash: Inapplicable
Deal Type: Inapplicable January 27, 2025
Lead Product(s) : Zoster Vaccine Recombinant, Adjuvanted
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase III
Partner/Sponsor/Collaborator : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
EMA Reviews GSK’s Shingrix New Prefilled Syringe Presentation
Details : Shingrix (recombinant zoster vaccine) is a non-live, recombinant subunit vaccine, being evaluated as a prefilled syringe administration for prevention of shingles in at-risk adults aged 18 and over.
Product Name : Shingrix
Product Type : Vaccine
Upfront Cash : Inapplicable
January 27, 2025
Details:
Nucala (mepolizumab) is the first targeted anti-Interleukin-5 (IL-5) biologic. It is approved as an add-on maintenance treatment for adults with chronic rhinosinusitis with nasal polyps.
Lead Product(s): Mepolizumab
Therapeutic Area: Pulmonary/Respiratory Diseases Brand Name: Nucala
Study Phase: Approved FDFProduct Type: Antibody
Sponsor: Inapplicable
Deal Size: Inapplicable Upfront Cash: Inapplicable
Deal Type: Inapplicable January 03, 2025
Lead Product(s) : Mepolizumab
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Approved FDF
Partner/Sponsor/Collaborator : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
GSK’s Nucala Bags Another China Approval, but Biggest Test Yet to Come
Details : Nucala (mepolizumab) is the first targeted anti-Interleukin-5 (IL-5) biologic. It is approved as an add-on maintenance treatment for adults with chronic rhinosinusitis with nasal polyps.
Product Name : Nucala
Product Type : Antibody
Upfront Cash : Inapplicable
January 03, 2025
Details:
Jemperli (dostarlimab, targets PD-1) in combination with Zejula (niraparib, targets PARP) is being evaluated as a first line treatment in phase 3 ciical trials of ovarian cancer.
Lead Product(s): Dostarlimab,Niraparib Tosylate
Therapeutic Area: Oncology Brand Name: Jemperli
Study Phase: Phase IIIProduct Type: Antibody
Sponsor: Inapplicable
Deal Size: Inapplicable Upfront Cash: Inapplicable
Deal Type: Inapplicable December 20, 2024
Lead Product(s) : Dostarlimab,Niraparib Tosylate
Therapeutic Area : Oncology
Highest Development Status : Phase III
Partner/Sponsor/Collaborator : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
GSK Announces FIRST Trial Met Primary Endpoint in Advanced Ovarian Cancer
Details : Jemperli (dostarlimab, targets PD-1) in combination with Zejula (niraparib, targets PARP) is being evaluated as a first line treatment in phase 3 ciical trials of ovarian cancer.
Product Name : Jemperli
Product Type : Antibody
Upfront Cash : Inapplicable
December 20, 2024
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