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The partnership helps identify patients whose cancers harbor the PTCH1 mutation and may be eligible for Endeavor’s clinical trial for ENV-101 (taladegib). The xCures platform also enables patients to find more suitable treatment options if they are ineligible.


Lead Product(s): Taladegib

Therapeutic Area: Oncology Product Name: ENV-101

Highest Development Status: Phase IIProduct Type: Small molecule

Recipient: Endeavor Biomedicines

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Partnership May 31, 2022

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US FDA granted their IND for an intermediate Expanded Access Program (EAP) for the ERK inhibitor ulixertinib (BVD-523). This intermediate-sized expanded access program is currently open and available for physicians interested in treating their patients.


Lead Product(s): Ulixertinib

Therapeutic Area: Oncology Product Name: BVD-523

Highest Development Status: Phase I/ Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable September 28, 2020

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