Find Isoquercitrin manufacturers, exporters & distributors on PharmaCompass

PharmaCompass

Synopsis

Related ProductsRelated Products

Synopsis

ACTIVE PHARMA INGREDIENTS

0

API Suppliers

API Suppliers

0

USDMF

US DMFs Filed

0

CEP/COS

CEP/COS Certifications

0

JDMF

JDMFs Filed

0

EU WC

EU WC

0

KDMF

KDMF

0

VMF

NDC API

0

Listed Suppliers

Other Suppliers

API REF. PRICE (USD/KG)

$
$ 0

MARKET PLACE

0

API

0

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

0

FDA Orange Book

FDA (Orange Book)

0

Europe

Europe

0

Canada

Canada

0

Australia

Australia

0

South Africa

South Africa

FDF Dossiers

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

0

EDQM

0

USP

0

JP

PATENTS & EXCLUSIVITIES

0

US Patents

0

US Exclusivities

0

Health Canada Patents

DIGITAL CONTENT

0

Data Compilation #PharmaFlow

0

Stock Recap #PipelineProspector

0

Weekly News Recap #Phispers

GLOBAL SALES INFORMATION

US Medicaid

NA

Annual Reports

NA

Finished Drug Prices

NA

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

Click the arrow to open the dropdown
read-moreClick the button for full data set
Also known as: Isoquercetin, 482-35-9, Hirsutrin, 3-glucosylquercetin, Quercetin 3-o-glucopyranoside, Quercetin 3-glucoside
Molecular Formula
C21H20O12
Molecular Weight
464.4  g/mol
InChI Key
OVSQVDMCBVZWGM-QSOFNFLRSA-N
FDA UNII
6HN2PC637T

Isoquercitrin
Isoquercetin is an orally bioavailable, glucoside derivative of the flavonoid quercetin and protein disulfide isomerase (PDI) inhibitor, with antioxidant and potential antithrombotic activity. As an antioxidant, isoquercetin scavenges free radicals and inhibits oxidative damage to cells. As a PDI inhibitor, this agent blocks PDI-mediated platelet activation, and fibrin generation, which prevents thrombus formation after vascular injury. In addition, isoquercetin is an alpha-glucosidase inhibitor. PDI, an oxidoreductase secreted by activated endothelial cells and platelets, plays a key role in the initiation of the coagulation cascade. Cancer, in addition to other thrombotic disorders, increases the risk of thrombus formation.
1 2D Structure

Isoquercitrin

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one
2.1.2 InChI
InChI=1S/C21H20O12/c22-6-13-15(27)17(29)18(30)21(32-13)33-20-16(28)14-11(26)4-8(23)5-12(14)31-19(20)7-1-2-9(24)10(25)3-7/h1-5,13,15,17-18,21-27,29-30H,6H2/t13-,15-,17+,18-,21+/m1/s1
2.1.3 InChI Key
OVSQVDMCBVZWGM-QSOFNFLRSA-N
2.1.4 Canonical SMILES
C1=CC(=C(C=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)OC4C(C(C(C(O4)CO)O)O)O)O)O
2.1.5 Isomeric SMILES
C1=CC(=C(C=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)O)O
2.2 Other Identifiers
2.2.1 UNII
6HN2PC637T
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 2-(3,4-dihydroxyphenyl)-3-(beta-d-glucofuranosyloxy)-5,7-dihydroxy-4h-1-benzopyran-4-one

2. 4h-1-benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-3-(beta-d-glucofuranosyloxy)-5,7-dihydroxy

3. Flavone, 3,3',4',5,7-pentahydroxy-, 3-beta-d-glucofuranoside

4. Isoquercetin

5. Isoquercitin

6. Isoquercitroside

7. Isotrifoliin

8. Quercetin 3-(beta-d-glucofuranoside)

9. Quercetin 3-o-beta-d-glucofuranoside

10. Quercetin-3-glucoside

11. Quercetin-3-o-beta-glucoside

12. Quercetin-3-o-glucoside

13. Trifoliin

14. Trifoliin A

2.3.2 Depositor-Supplied Synonyms

1. Isoquercetin

2. 482-35-9

3. Hirsutrin

4. 3-glucosylquercetin

5. Quercetin 3-o-glucopyranoside

6. Quercetin 3-glucoside

7. Isotrifoliin

8. Quercetin 3-d-glucoside

9. Quercetin 3-o-glucoside

10. Quercetol 3-monoglucoside

11. Glucosyl 3-quercetin

12. Contigoside B

13. Quercetol 3-glucoside

14. Quercetin-3-o-glucopyranoside

15. Quercetin-3-o-glucoside

16. Quercetin 3-monoglucoside

17. Quercetin 3-beta-glucoside

18. Quercetin-3-glucoside

19. Quercetin 3-beta-o-glucoside

20. Quercetin Glucoside

21. Quercetin-3-glucose

22. Ronacare Isoquercetin

23. Glucosyl-3-quercetin

24. Isoquercetin, (-)-

25. 3-beta-d-glucosylquercetin

26. Quercetin 3.beta.-glucoside

27. 6hn2pc637t

28. Chembl250450

29. Chebi:68352

30. 3,3',4',5,7-pentahydroxyflavone 3-beta-glucoside

31. Quercetin 3-o-.beta.-d-glucopyranoside

32. 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-(((2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2h-pyran-2-yl)oxy)-4h-chromen-4-one

33. Quercetin 3-beta-d-glucoside

34. Quercetin 3-o-beta-d-glucopyranoside

35. Nsc-115918

36. Nsc-407304

37. Quercetin 3-o-beta-d-glucoside

38. 2-(3,4-dihidroxyphenyl)-3-(beta-d-glucofuranosyloxy)-5,7-dihydroxy-4h-1-benzopyran-4-one

39. 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-((2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2h-pyran-2-yloxy)-4h-chromen-4-one

40. Smr000466391

41. Nsc 115918

42. Brn 0100989

43. Hydroside

44. Unii-6hn2pc637t

45. Ccris 9340

46. Isoquercitrin (6)

47. Mfcd00017746

48. Acacia

49. 3-glucoside Isoquercitrin

50. Quercetin 3--d-glucoside

51. Isoquercitrin [mi]

52. Isoquercetin [inci]

53. Quercetin 3-glucopyranoside

54. Quercetin 3-ss-d-glucoside

55. 4-18-00-03493 (beilstein Handbook Reference)

56. Mls000759532

57. Mls001424096

58. Q 5

59. Schembl181306

60. Acon1_002134

61. Cid_5280804

62. Cid_5378597

63. Quercetin 3- Beta -d-glucoside

64. Quercetin 3-o--d-glucofuranoside

65. Bdbm153265

66. Hms2051b17

67. Quercetin-3-o-beta-glucopyranoside

68. Hy-n1445

69. Zinc4096845

70. Bdbm50241354

71. Pdsp1_001363

72. Pdsp2_001347

73. S3842

74. Akos015896729

75. Ccg-100967

76. Db12665

77. Nc00217

78. Quercetin-3-o-beta-d-galactopyranoside

79. 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4h-chromen-3-yl Beta-d-glucopyranoside

80. 4h-1-benzopyran-4-one, 5,7-dihydroxy-2-(3,4-dihydroxyphenyl)-3-(beta-d-glucopyranosyloxy)-

81. 4h-1-benzopyran-4-one,2-(3,4-dihydroxyphenyl)-3-(b-d-glucopyranosyloxy)-5,7-dihydroxy-

82. Quercetin -3-o-beta-d-galactopyranoside

83. As-35335

84. Quercetin-3-o-.beta.-d-glucoside

85. Quercetin 3-glucoside, Analytical Standard

86. Quercetin-3-.beta.-glucopyranoside

87. 3-o-.beta.-d-glucopyranosylquercetin

88. Cs-0016884

89. C05623

90. Quercetin 3-o-glucopyranoside [who-dd]

91. Ab00639942-06

92. Quercetin 3-beta-d-glucoside, >=90% (hplc)

93. 3,3',4',5,7-pentahydroxyflavone 3-a-glucoside

94. A871939

95. 3-glucopyranosyloxy-3',4',5,7-tetrahydroxyflavone

96. Q-100268

97. Q6086296

98. Brd-k73991644-001-01-7

99. 3,3'',4'',5,7-pentahydroxyflavone-3-beta-o-glucoside

100. Isoquercitrin, Primary Pharmaceutical Reference Standard

101. Quercetin 3-o-glucoside (constituent Of Ginkgo) [dsc]

102. 3',4',5,7-tetrahydroxyflavone-3-.beta.-d-glucopyranoside

103. 2-(3,4-dihydroxyphenyl)-3-(beta-d-glucopyranosyloxy)-5,7-dihydroxy-4h-1-benzopyran-4-one

104. 2-hydroxy-4-(3,5,7-trihydroxy-4-oxo-4h-chromen-2-yl)phenyl B-d-glucopyranoside

105. 2-(3,4-dihydroxy-phenyl)-5,7-dihydroxy-3-(3,4,5-trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-chromen-4-one

106. 2-(3,4-dihydroxyphenyl)-3-(b-d-glucopyranosyloxy)-5,7-dihydroxy-4h-1-benzopyran-4-one, 9ci

107. 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-((2s,3r,4s,5r,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)-tetrahydro-2h-pyran-2-yloxy)-4h-chromen-4-one

108. 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-((2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)-tetrahydro-2h-pyran-2-yloxy)-4h-chromen-4-one

109. 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-chromen-4-one

110. 4h-1-benzopyran-4-one, 2- (3,4-dihydroxyphenyl)-3- (ss-d-glucofuranosyloxy)-5,7-dihydroxy-

111. 4h-1-benzopyran-4-one, 2-(3,4-dihydroxy-phenyl)-3-(.beta.-d-glucofuranosyloxy)-5,7-dihydroxy-

112. 4h-1-benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-3-(.beta.-d-glucopyranosyloxy)-5,7-dihydroxy-

113. Hw2

2.4 Create Date
2005-06-24
3 Chemical and Physical Properties
Molecular Weight 464.4 g/mol
Molecular Formula C21H20O12
XLogP30.4
Hydrogen Bond Donor Count8
Hydrogen Bond Acceptor Count12
Rotatable Bond Count4
Exact Mass464.09547607 g/mol
Monoisotopic Mass464.09547607 g/mol
Topological Polar Surface Area207 Ų
Heavy Atom Count33
Formal Charge0
Complexity758
Isotope Atom Count0
Defined Atom Stereocenter Count5
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 FDA Pharmacological Classification
4.1.1 Pharmacological Classes
Cell-mediated Immunity [PE]; Increased Histamine Release [PE]; Increased IgG Production [PE]; Non-Standardized Plant Allergenic Extract [EPC]; Plant Proteins [CS]; Allergens [CS]

Digital Content read-more

Create Content with PharmaCompass, ask us

NEWS #PharmaBuzz

read-more
read-more

REF. STANDARDS & IMPURITIES

Upload your portfolio for free, ask us

ABOUT THIS PAGE

Ask Us for Pharmaceutical Supplier and Partner
Ask Us, Find A Supplier / Partner
No Commissions, No Strings Attached, Get Connected for FREE

What are you looking for?

How can we help you?

The request can't be empty

Please read our Privacy Policy carefully

You must agree to the privacy policy

The name can't be empty
The company can't be empty.
The email can't be empty Please enter a valid email.
The mobile can't be empty