2,4-Dihydroxy-6,7-dimethoxyquinazoline

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4 End Use APIs
46 Related Intermediates

Chemistry

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Also known as: 28888-44-0, 6,7-dimethoxyquinazoline-2,4-dione, 2,4-dihydroxy-6,7-dimethoxyquinazoline, 6,7-dimethoxyquinazoline-2,4-diol, 6,7-dimethoxy-1h-quinazoline-2,4-dione, 6,7-dimethoxy-2,4-quinazolinedione

Molecular Formula

C₁₀H₁₀N₂O₄

Molecular Weight

222.20 g/mol

InChI Key

KWNQIIMVPSMYEM-UHFFFAOYSA-N

FDA UNII

K7867Z125J

1 2D Structure

28888-44-0

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

6,7-dimethoxy-1H-quinazoline-2,4-dione

2.1.2 InChI

InChI=1S/C10H10N2O4/c1-15-7-3-5-6(4-8(7)16-2)11-10(14)12-9(5)13/h3-4H,1-2H3,(H2,11,12,13,14)

2.1.3 InChI Key

KWNQIIMVPSMYEM-UHFFFAOYSA-N

2.1.4 Canonical SMILES

COC1=C(C=C2C(=C1)C(=O)NC(=O)N2)OC

2.2 Other Identifiers

2.2.1 UNII

K7867Z125J

2.3 Synonyms

2.3.1 Depositor-Supplied Synonyms

1. 28888-44-0

2. 6,7-dimethoxyquinazoline-2,4-dione

3. 2,4-dihydroxy-6,7-dimethoxyquinazoline

4. 6,7-dimethoxyquinazoline-2,4-diol

5. 6,7-dimethoxy-1h-quinazoline-2,4-dione

6. 6,7-dimethoxy-2,4-quinazolinedione

7. 2,4(1h,3h)-quinazolinedione, 6,7-dimethoxy-

8. 6,7-dimethoxy-2,4(1h,3h)-quinazolinedione

9. 6,7-dimethoxy-(1h,3h)-2,4-quinazolindione

10. 2888-44-0

11. 6,7-dimethoxy-1,2,3,4-tetrahydroquinazoline-2,4-dione

12. K7867z125j

13. Ncgc00160264-01

14. Dsstox_cid_26100

15. Dsstox_rid_81338

16. Dsstox_gsid_46100

17. Cas-28888-44-0

18. Quinazolindione

19. Unii-k7867z125j

20. Einecs 249-288-1

21. 2,4-dihydroxy-6,7-dimethoxquinazoline

22. Doxazosin Impurity D

23. Oprea1_517280

24. Amy244

25. Schembl2330774

26. Chembl1403860

27. Dtxsid9046100

28. Zinc120622

29. Bcp09514

30. Doxazosin Related Compound B

31. Tox21_111752

32. Bbl028249

33. Mfcd00023889

34. Stk400208

35. Stl083699

36. 6,7-dimethoxy-quinazoline-2,4-diol

37. 6,7-dimethoxy Quinazoline-2,4-dione

38. Akos000120307

39. Akos005712782

40. Tox21_111752_1

41. 6,7-dimethoxy-2,4-quinazolinediol #

42. Ac-8386

43. Bs-4302

44. Dimethoxy-2,4(1h,3h)-quinazolinedione

45. Ncgc00263562-01

46. Quinazoline-2,4-diol, 6,7-dimethoxy-

47. 2,4-dihydroxy-6,7-dimethoxy Quinazoline

48. 6,7-dimethoxy-2,4-dihydroxy Quinazoline

49. 6,7-dimethoxy-2,4-quinazolinedione, 97%

50. Db-019954

51. A5439

52. Cs-0016028

53. D1839

54. Ft-0620865

55. Doxazosin Related Compound B [usp-rs]

56. 88d440

57. 1,2-bis(diphenylphosphino)ethanemonooxide

58. 888d440

59. Sr-01000945181

60. Doxazosin Mesilate Impurity D [ep Impurity]

61. Sr-01000945181-1

62. W-107022

63. 3-methyl-4-oxo-2-phenyl-4h-chromene-8-carbonitrile

64. Q27282043

65. Usp Doxazosin Related Compound B [usp Impurity]

66. Ncgc00160264-01!6,7-dimethoxy-quinazoline-2,4-diol

67. Doxazosin Impurity D, European Pharmacopoeia (ep) Reference Standard

68. Doxazosin Related Compound B, United States Pharmacopeia (usp) Reference Standard

2.4 Create Date

2005-03-27

3 Chemical and Physical Properties

Molecular Formula	C₁₀H₁₀N₂O₄
Molecular Weight	222.20 g/mol
XLogP3	0.7
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	2
Exact Mass	222.06405680 g/mol
Monoisotopic Mass	222.06405680 g/mol
Topological Polar Surface Area	76.7 Å²
Heavy Atom Count	16
Formal Charge	0
Complexity	307
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1