CAS 20980-22-7 manufacturers and suppliers on PharmaCompass

PharmaCompass

Chemistry

Click the arrow to open the dropdown
read-moreClick the button for full data set
Also known as: 20980-22-7, 1-(2-pyrimidyl)piperazine, 2-(piperazin-1-yl)pyrimidine, 1-(2-pyrimidinyl)piperazine, 2-piperazin-1-ylpyrimidine, 2-piperazinopyrimidine
Molecular Formula
C8H12N4
Molecular Weight
164.21  g/mol
InChI Key
MRBFGEHILMYPTF-UHFFFAOYSA-N
FDA UNII
H3B5B38F56

CAS 20980-22-7
1 2D Structure

CAS 20980-22-7

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
2-piperazin-1-ylpyrimidine
2.1.2 InChI
InChI=1S/C8H12N4/c1-2-10-8(11-3-1)12-6-4-9-5-7-12/h1-3,9H,4-7H2
2.1.3 InChI Key
MRBFGEHILMYPTF-UHFFFAOYSA-N
2.1.4 Canonical SMILES
C1CN(CCN1)C2=NC=CC=N2
2.2 Other Identifiers
2.2.1 UNII
H3B5B38F56
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 1-(2-pyrimidinyl)piperazine

2. 1-pyrimidinylpiperazine

3. Mj 13653

4. Mj-13653

2.3.2 Depositor-Supplied Synonyms

1. 20980-22-7

2. 1-(2-pyrimidyl)piperazine

3. 2-(piperazin-1-yl)pyrimidine

4. 1-(2-pyrimidinyl)piperazine

5. 2-piperazin-1-ylpyrimidine

6. 2-piperazinopyrimidine

7. Pyrimidine, 2-(1-piperazinyl)-

8. 2-piperazin-1-yl-pyrimidine

9. 1-pp

10. 1-(2-pyrimidyl) Piperazine

11. Mfcd00040742

12. N-(2-pyrimidinyl)piperazine

13. 1-(2-pyrimidyl)-piperazine

14. 1-pyrimidin-2-yl-piperazine

15. 4-(2-pyrimidinyl)piperazine

16. 1-(2-pyrimidinyl)-piperazine

17. 1-(pyrimidin-2-yl)piperazine

18. 125523-53-7

19. 1-pyrimidinylpiperazine

20. 2-(piperazinyl)pyrimidine

21. Chembl724

22. 1-(2-pyrimidinyl) Piperazine

23. Campiron

24. Campirone

25. H3b5b38f56

26. Kampirone

27. 2-piperazino-pyrimidine

28. Pyrimidinylpiperazine

29. Buspirone Ep Impurity A

30. Einecs 244-135-5

31. 1-pyrimidyl Piperazine

32. Brn 0151178

33. Mj 13653

34. Maybridge1_004282

35. N-(2-pyrimidyl)piperazine

36. (s)-homoserinehydrochloride

37. 1-(2-pyrimidyl)piperizine

38. 1-(2pyrimidinyl)piperazine

39. 1-pyrimidin-2-ylpiperazine

40. 1-pyrimidin-2-yl-piperazin

41. 2-piperazin-1-yl Pyrimidine

42. Buspirone Related Compound A

43. 1-(2-pyrimidinyl) Piperzine

44. N-(pyrimidin-2-yl)piperazine

45. Schembl169214

46. Unii-h3b5b38f56

47. 2- (1-piperazinyl)pyrimidine

48. 2-(1-piperazinyl)-pyrimidine

49. 4-(2-pyrimidinyl) Piperazine

50. 1-(pyrimidine-2-yl)piperazine

51. 2-(1-piperazinyl)pyrimidine #

52. Mrbfgehilmyptf-uhfffaoysa-

53. Zinc66064

54. Dtxsid00864967

55. Chebi:166562

56. 1-(2-pyrimidyl)piperazine, 98%

57. Bdbm50007403

58. Pdsp1_000483

59. Pdsp2_000481

60. Stk088200

61. Akos000264519

62. Ac-1840

63. Am62510

64. Cs-w004464

65. Fs-1244

66. Hy-w004464

67. Sdccgmls-0065816.p001

68. Ncgc00247000-01

69. Bp-13017

70. Db-027250

71. Bb 0248124

72. Ft-0605569

73. Ft-0673928

74. P1110

75. Buspirone Related Compound A [usp-rs]

76. En300-33983

77. F11219

78. 4-25-00-02083 (beilstein Handbook Reference)

79. 980p227

80. Buspirone Metabolite (1-(2-pyrimidyl)-piperazine)

81. Buspirone Related Compound A [usp Impurity]

82. Q7263602

83. W-107583

84. Buspirone Hydrochloride Impurity A [ep Impurity]

85. Buspirone Related Compound A, United States Pharmacopeia (usp) Reference Standard

86. Buspirone Usp Rc A; 2-(piperazin-1-yl)pyrimidine; 2-(1-piperazinyl)pyrimidine; 1-(2-pyrimidinyl)piperazine; 2-piperazinopyrimidine; 4-(2-pyrimidinyl)piperazine

2.4 Create Date
2005-03-27
3 Chemical and Physical Properties
Molecular Weight 164.21 g/mol
Molecular Formula C8H12N4
XLogP30
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count1
Exact Mass164.106196400 g/mol
Monoisotopic Mass164.106196400 g/mol
Topological Polar Surface Area41 Ų
Heavy Atom Count12
Formal Charge0
Complexity127
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Adrenergic alpha-Antagonists

Drugs that bind to but do not activate alpha-adrenergic receptors thereby blocking the actions of endogenous or exogenous adrenergic agonists. Adrenergic alpha-antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma. (See all compounds classified as Adrenergic alpha-Antagonists.)


Anti-Anxiety Agents

Agents that alleviate ANXIETY, tension, and ANXIETY DISORDERS, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions. ADRENERGIC BETA-ANTAGONISTS are commonly used in the symptomatic treatment of anxiety but are not included here. (See all compounds classified as Anti-Anxiety Agents.)


4.2 Metabolism/Metabolites

2-(1-piperazinyl)pyrimidine has known human metabolites that include 2-(Piperazin-1-yl)pyrimidin-5-ol.

2-(1-piperazinyl)pyrimidine is a known human metabolite of gepirone.

S73 | METXBIODB | Metabolite Reaction Database from BioTransformer | DOI:10.5281/zenodo.4056560


BUILDING BLOCK

Upload your portfolio for free, ask us

END USE APIs

read-more
read-more
Ask Us for Pharmaceutical Supplier and Partner
Ask Us, Find A Supplier / Partner
No Commissions, No Strings Attached, Get Connected for FREE

What are you looking for?

How can we help you?

The request can't be empty

Please read our Privacy Policy carefully

You must agree to the privacy policy

The name can't be empty
The company can't be empty.
The email can't be empty Please enter a valid email.
The mobile can't be empty