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CAS 7677-24-9
Also known as: 7677-24-9, Trimethylsilanecarbonitrile, Cyanotrimethylsilane, Trimethylsilylcyanide, Trimethylsilylformonitrile, Silanecarbonitrile, trimethyl-
Molecular Formula
C4H9NSi
Molecular Weight
99.21  g/mol
InChI Key
LEIMLDGFXIOXMT-UHFFFAOYSA-N

Trimethylsilyl cyanide is a chemical compound of cyanide. It is used in organic synthesis. (L106)
1 2D Structure

CAS 7677-24-9

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
trimethylsilylformonitrile
2.1.2 InChI
InChI=1S/C4H9NSi/c1-6(2,3)4-5/h1-3H3
2.1.3 InChI Key
LEIMLDGFXIOXMT-UHFFFAOYSA-N
2.1.4 Canonical SMILES
C[Si](C)(C)C#N
2.2 Synonyms
2.2.1 MeSH Synonyms

1. Tmscn

2.2.2 Depositor-Supplied Synonyms

1. 7677-24-9

2. Trimethylsilanecarbonitrile

3. Cyanotrimethylsilane

4. Trimethylsilylcyanide

5. Trimethylsilylformonitrile

6. Silanecarbonitrile, Trimethyl-

7. Trimethylsilylnitrile

8. Trimethylsilane Carbonitrile

9. Trimethylsilylcarbonitrile

10. Mfcd00001765

11. Tms Cyanide

12. Tmscn

13. Trimethyl Silyl Cyanide

14. Trimethyl Silane Cyanide

15. Tms-cyanide

16. Cyanotrimethlysilane

17. Trimethylcyanosilane

18. Trimethylsilylcyanid

19. Trimethysilylcyanide

20. Cyanotrimethyl Silane

21. Cyanotrimethyl-silane

22. Einecs 231-657-3

23. Trimethysilyl Cyanide

24. Me3sicn

25. Trimethylsilanecyanide

26. Tri-methylsilylcyanide

27. Trimethyl Silylcyanide

28. Trimethylsilyl-cyanide

29. Trimethyl Cyano Silane

30. Tri-methylsilyl Cyanide

31. Trimethyl-silyl Cyanide

32. (trimethylsilyl)cyanide

33. Trimethyl Silyl Nitrile

34. Tms-cn

35. Trimethylsilyl-formonitrile

36. Trimethylsilylcyanide,99%

37. Trimethylsilylmethanenitrile

38. (ch3)3sicn

39. (trimethylsilyl)formonitrile

40. Trimethylsilanecarbonitrile #

41. Trimethylsilyl Cyanide, 98%

42. Trimethylsilyl Cyanide, 97%

43. Dtxsid9064766

44. Amy6985

45. Act02612

46. Albb-018705

47. Bcp25853

48. Trimethylsilyl Cyanide-[13c,15n]

49. Bbl036271

50. Stl558690

51. Akos000121901

52. Zinc169743077

53. Pb23143

54. Bp-11377

55. Ls-06137

56. Db-030488

57. Cs-0015833

58. Ft-0647485

59. T0990

60. En300-29571

61. S19150

62. Trimethylsilyl Cyanide, Technical, >=95% (gc)

63. A838824

64. Q3008073

65. F0001-1959

2.3 Create Date
2005-03-27
3 Chemical and Physical Properties
Molecular Weight 99.21 g/mol
Molecular Formula C4H9NSi
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count1
Rotatable Bond Count0
Exact Mass g/mol
Monoisotopic Mass g/mol
Topological Polar Surface Area23.8
Heavy Atom Count6
Formal Charge0
Complexity81.5
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Drug and Medication Information
4.1 Minimum/Potential Fatal Human Dose

200 to 300 milligrams for an adult human (cyanide salts). (T86)


5 Pharmacology and Biochemistry
5.1 Metabolism/Metabolites

Organic nitriles are converted into cyanide ions through the action of cytochrome P450 enzymes in the liver. Cyanide is rapidly absorbed and distributed throughout the body. Cyanide is mainly metabolized into thiocyanate by either rhodanese or 3-mercaptopyruvate sulfur transferase. Cyanide metabolites are excreted in the urine. (L96)


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