Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Lutetium-177 Vipivotide Tetraxetan,68Ga-PSMA-11
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Novartis Plans to File for Pluvicto Pre-Taxane Label Expansion in H2 2024
Details : Pluvicto (lutetium Lu 177 vipivotide tetraxetan) is a prostate-specific membrane antigen, which is approved for the treatment of PSMA-positive metastatic castration-resistant prostate cancer.
Brand Name : Pluvicto
Molecule Type : Large molecule
Upfront Cash : Not Applicable
April 04, 2024
Lead Product(s) : Lutetium-177 Vipivotide Tetraxetan,68Ga-PSMA-11
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Lutetium-177 Vipivotide Tetraxetan
Therapeutic Area : Oncology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Novartis Expands Pluvicto Production With Largest Advanced Manufacturing Facility
Details : Pluvicto (lutetium Lu 177 vipivotide tetraxetan) is a prostate-specific membrane antigen which is approved for the treatment of PSMA-positive metastatic castration-resistant prostate cancer.
Brand Name : Pluvicto
Molecule Type : Small molecule
Upfront Cash : Not Applicable
January 05, 2024
Lead Product(s) : Lutetium-177 Vipivotide Tetraxetan
Therapeutic Area : Oncology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Lutetium-177 Vipivotide Tetraxetan
Therapeutic Area : Oncology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Pluvicto® is an intravenous radioligand therapy combining a targeting compound (a ligand) with a therapeutic radionuclide (a radioactive particle, in this case lutetium-177).
Brand Name : Pluvicto
Molecule Type : Large molecule
Upfront Cash : Not Applicable
December 13, 2022
Lead Product(s) : Lutetium-177 Vipivotide Tetraxetan
Therapeutic Area : Oncology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Lutetium-177 Vipivotide Tetraxetan
Therapeutic Area : Oncology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Pluvicto (lutetium Lu 177 vipivotide tetraxetan) is an intravenous radioligand therapy combining a targeting compound (a ligand) with a therapeutic radionuclide (a radioactive particle, in this case lutetium-177).
Brand Name : Pluvicto
Molecule Type : Large molecule
Upfront Cash : Not Applicable
December 05, 2022
Lead Product(s) : Lutetium-177 Vipivotide Tetraxetan
Therapeutic Area : Oncology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Lutetium-177 Vipivotide Tetraxetan
Therapeutic Area : Oncology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : The positive CHMP opinion is based on Phase III VISION study, in which Pluvicto plus BSoC demonstrated significantly improved overall survival in PSMA-positive mCRPC patients previously treated with AR pathway inhibition and taxane-based chemotherapy com...
Brand Name : Pluvicto
Molecule Type : Large molecule
Upfront Cash : Not Applicable
October 14, 2022
Lead Product(s) : Lutetium-177 Vipivotide Tetraxetan
Therapeutic Area : Oncology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Lutetium-177 Vipivotide Tetraxetan
Therapeutic Area : Oncology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Pluvicto® (lutetium (177Lu) vipivotide tetraxetan) is indicated for the treatment of adult patients with PSMA-positive mCRPC who have been treated with AR pathway inhibition and taxane-based chemotherapy or who are not medically suitable for taxanes.
Brand Name : Pluvicto
Molecule Type : Large molecule
Upfront Cash : Not Applicable
August 11, 2022
Lead Product(s) : Lutetium-177 Vipivotide Tetraxetan
Therapeutic Area : Oncology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Lutetium-177 Vipivotide Tetraxetan
Therapeutic Area : Oncology
Study Phase : Approved
Sponsor : Novartis Pharmaceuticals Corporation
Deal Size : Undisclosed
Deal Type : Collaboration
Lantheus Announces Collaboration to Support Prostate Cancer Clinical Development
Details : As part of the agreement with Novartis, Lantheus will provide PYLARIFY for the selection of patients with prostate cancer and Novartis will provide all PYLARIFY related clinical imaging data to Lantheus.
Brand Name : Pluvicto
Molecule Type : Large molecule
Upfront Cash : Undisclosed
March 29, 2022
Lead Product(s) : Lutetium-177 Vipivotide Tetraxetan
Therapeutic Area : Oncology
Highest Development Status : Approved
Sponsor : Novartis Pharmaceuticals Corporation
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Lutetium-177 Vipivotide Tetraxetan
Therapeutic Area : Oncology
Study Phase : Approved
Sponsor : Advanced Accelerator Applications
Deal Size : $172.0 million
Deal Type : Agreement
Details : Advanced Accelerator Applications (AAA) and Endocyte, Inc., both Novartis companies, successfully completed full-scale development of Pluvicto and also received Breakthrough Therapy designation from the U.S. FDA last year.
Brand Name : Pluvicto
Molecule Type : Large molecule
Upfront Cash : $12.0 million
March 29, 2022
Lead Product(s) : Lutetium-177 Vipivotide Tetraxetan
Therapeutic Area : Oncology
Highest Development Status : Approved
Sponsor : Advanced Accelerator Applications
Deal Size : $172.0 million
Deal Type : Agreement
Lead Product(s) : Lutetium-177 Vipivotide Tetraxetan
Therapeutic Area : Oncology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : ITM to supply Advanced Accelerator Applications on an industrial scale with its high-quality n.c.a. lutetium-177 as core component of newly approved radiotherapeutic, Pluvicto for treatment of adult patients with prostate-specific membrane antigen and po...
Brand Name : Pluvicto
Molecule Type : Large molecule
Upfront Cash : Not Applicable
March 25, 2022
Lead Product(s) : Lutetium-177 Vipivotide Tetraxetan
Therapeutic Area : Oncology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Lutetium-177 Vipivotide Tetraxetan
Therapeutic Area : Oncology
Study Phase : Approved
Sponsor : Advanced Accelerator Applications
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : FDA approval was based on VISION trial, where patients with pre-treated PSMA-positive mCRPC who received Pluvicto plus standard of care had a statistically significant reduction in risk of death1; both alternate primary endpoints of OS and radiographic P...
Brand Name : Pluvicto
Molecule Type : Large molecule
Upfront Cash : Not Applicable
March 23, 2022
Lead Product(s) : Lutetium-177 Vipivotide Tetraxetan
Therapeutic Area : Oncology
Highest Development Status : Approved
Sponsor : Advanced Accelerator Applications
Deal Size : Not Applicable
Deal Type : Not Applicable
LOOKING FOR A SUPPLIER?