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    [{"orgOrder":0,"company":"2Seventy Bio","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2021","type":"Not Applicable","leadProduct":"Idecabtagene Vicleucel","moa":"B-Cell maturation antigen","graph1":"Oncology","graph2":"Approved","graph3":"2Seventy Bio","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Dispersion for Infusion","sponsorNew":"2Seventy Bio \/ Not Applicable","highestDevelopmentStatusID":"12","companyTruncated":"2Seventy Bio \/ Not Applicable"},{"orgOrder":0,"company":"2Seventy Bio","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2021","type":"Not Applicable","leadProduct":"BB21217","moa":"","graph1":"Oncology","graph2":"Phase I","graph3":"2Seventy Bio","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Inhalation","sponsorNew":"2Seventy Bio \/ Not Applicable","highestDevelopmentStatusID":"6","companyTruncated":"2Seventy Bio \/ Not Applicable"},{"orgOrder":0,"company":"2Seventy Bio","sponsor":"Novo Nordisk","pharmaFlowCategory":"D","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Cell and Gene therapy","year":"2022","type":"Collaboration","leadProduct":"MegaTAL mRNA","moa":"","graph1":"Genetic Disease","graph2":"Undisclosed","graph3":"2Seventy Bio","amount2":0.040000000000000001,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Genetic Disease","amount2New":0.040000000000000001,"dosageForm":"","sponsorNew":"2Seventy Bio \/ Novo Nordisk","highestDevelopmentStatusID":"1","companyTruncated":"2Seventy Bio \/ Novo Nordisk"},{"orgOrder":0,"company":"2Seventy Bio","sponsor":"Genevant Sciences","pharmaFlowCategory":"D","therapeuticArea":"Genetic Disease","country":"CANADA","productType":"Cell and Gene therapy","year":"2022","type":"Licensing Agreement","leadProduct":"MegaTAL mRNA","moa":"","graph1":"Genetic Disease","graph2":"Undisclosed","graph3":"2Seventy Bio","amount2":0.040000000000000001,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Genetic Disease","amount2New":0.040000000000000001,"dosageForm":"","sponsorNew":"2Seventy Bio \/ 2seventy bio","highestDevelopmentStatusID":"1","companyTruncated":"2Seventy Bio \/ 2seventy bio"},{"orgOrder":0,"company":"2Seventy Bio","sponsor":"Bristol Myers Squibb","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2022","type":"Not Applicable","leadProduct":"Idecabtagene Vicleucel","moa":"B-Cell maturation antigen","graph1":"Oncology","graph2":"Approved","graph3":"2Seventy 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Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2022","type":"Partnership","leadProduct":"TCR T-cell Therapy","moa":"MAGE-A4","graph1":"Oncology","graph2":"Preclinical","graph3":"2Seventy Bio","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"2Seventy Bio \/ JW Therapeutics","highestDevelopmentStatusID":"4","companyTruncated":"2Seventy Bio \/ JW Therapeutics"},{"orgOrder":0,"company":"2Seventy Bio","sponsor":"Medigene","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"GERMANY","productType":"Cell and Gene therapy","year":"2023","type":"Partnership","leadProduct":"TCR-based Therapy","moa":"","graph1":"Oncology","graph2":"Preclinical","graph3":"2Seventy Bio","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"2Seventy Bio \/ 2seventy bio","highestDevelopmentStatusID":"4","companyTruncated":"2Seventy Bio \/ 2seventy bio"},{"orgOrder":0,"company":"2Seventy Bio","sponsor":"Goldman Sachs","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2023","type":"Public Offering","leadProduct":"Idecabtagene Vicleucel","moa":"","graph1":"Oncology","graph2":"Approved","graph3":"2Seventy Bio","amount2":0.13,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Oncology","amount2New":0.13,"dosageForm":"Infusion","sponsorNew":"2Seventy Bio \/ Goldman Sachs","highestDevelopmentStatusID":"12","companyTruncated":"2Seventy Bio \/ Goldman Sachs"},{"orgOrder":0,"company":"2Seventy Bio","sponsor":"Bristol Myers Squibb","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2023","type":"Not Applicable","leadProduct":"Idecabtagene Vicleucel","moa":"","graph1":"Oncology","graph2":"Approved","graph3":"2Seventy Bio","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Suspension for Infusion","sponsorNew":"2Seventy Bio \/ 2seventy bio","highestDevelopmentStatusID":"12","companyTruncated":"2Seventy Bio \/ 2seventy bio"},{"orgOrder":0,"company":"2Seventy Bio","sponsor":"Novo Nordisk","pharmaFlowCategory":"D","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Cell and Gene therapy","year":"2023","type":"Collaboration","leadProduct":"Undisclosed","moa":"","graph1":"Genetic Disease","graph2":"Undisclosed","graph3":"2Seventy Bio","amount2":0.040000000000000001,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Genetic Disease","amount2New":0.040000000000000001,"dosageForm":"","sponsorNew":"2Seventy Bio \/ Novo Nordisk","highestDevelopmentStatusID":"1","companyTruncated":"2Seventy Bio \/ Novo 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Bio","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"2Seventy Bio \/ 2Seventy Bio","highestDevelopmentStatusID":"12","companyTruncated":"2Seventy Bio \/ 2Seventy Bio"},{"orgOrder":0,"company":"2Seventy Bio","sponsor":"Novo Nordisk","pharmaFlowCategory":"D","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Cell and Gene therapy","year":"2024","type":"Divestment","leadProduct":"Undisclosed","moa":"","graph1":"Genetic Disease","graph2":"Preclinical","graph3":"2Seventy Bio","amount2":0.040000000000000001,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Genetic Disease","amount2New":0.040000000000000001,"dosageForm":"","sponsorNew":"2Seventy Bio \/ Novo Nordisk","highestDevelopmentStatusID":"4","companyTruncated":"2Seventy Bio \/ Novo Nordisk"},{"orgOrder":0,"company":"2Seventy Bio","sponsor":"Bristol Myers Squibb","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2024","type":"Not Applicable","leadProduct":"Fludarabine","moa":"","graph1":"Technology","graph2":"Approved","graph3":"2Seventy Bio","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Technology","amount2New":0.10000000000000001,"dosageForm":"","sponsorNew":"2Seventy Bio \/ 2seventy Bio","highestDevelopmentStatusID":"12","companyTruncated":"2Seventy Bio \/ 2seventy Bio"}]

    Find Clinical Drug Pipeline Developments & Deals by 2Seventy Bio

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                            01

                            2Seventy Bio

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                            Lead Product(s) : Idecabtagene Vicleucel,Lenalidomide,Fludarabine Phosphate

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Recipient : Bristol Myers Squibb

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Bristol Myers Squibb and 2seventy bio Update on KarMMa-9 Trial of Abecma in Myeloma

                            Details : Abecma (idecabtagene vicleucel) is a CAR T cell therapy which binds to BCMA on the surface of multiple myeloma cells. It is being evaluated for newly diagnosed multiple myeloma.

                            Brand Name : Abecma

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            September 25, 2024

                            Lead Product(s) : Idecabtagene Vicleucel,Lenalidomide,Fludarabine Phosphate

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Recipient : Bristol Myers Squibb

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            02

                            2Seventy Bio

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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Genetic Disease

                            Study Phase : Preclinical

                            Sponsor : Novo Nordisk

                            Deal Size : $40.0 million

                            Deal Type : Divestment

                            DEALS_DEV arrow-down

                            2seventy bio Sells Hemophilia A Candidate and MegaTAL Technology to Novo Nordisk for $40M

                            Details : Novo has acquired the Hemophilia A program and rights to 2seventy’s in vivo gene editing technology for autologous or allogeneic cell therapies of immune cells for the treatment of autoimmune disease.

                            Brand Name : Undisclosed

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            June 26, 2024

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Preclinical

                            Sponsor : Novo Nordisk

                            Deal Size : $40.0 million

                            Deal Type : Divestment

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                            03

                            2Seventy Bio

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                            Lead Product(s) : Idecabtagene Vicleucel

                            Therapeutic Area : Oncology

                            Study Phase : Approved

                            Recipient : Bristol Myers Squibb

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            FDA Approves Abecma for Triple-Class Exposed Myeloma After Two Prior Therapies

                            Details : Abecma (idecabtagene vicleucel) is a CAR T cell therapy for multiple myeloma, approved for treating triple-class exposed relapsed or refractory patients.

                            Brand Name : Abecma

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            April 05, 2024

                            Lead Product(s) : Idecabtagene Vicleucel

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved

                            Recipient : Bristol Myers Squibb

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            04

                            2Seventy Bio

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                            Lead Product(s) : Idecabtagene Vicleucel

                            Therapeutic Area : Oncology

                            Study Phase : Approved

                            Sponsor : Regeneron Pharmaceuticals

                            Deal Size : Undisclosed

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            Regeneron Forms Cell Medicines with Acquisition Of 2seventy Bio

                            Details : Regeneron will have full development and commercialization rights to its pipeline of investigational immune cell therapies, including Abecma (idecabtagene vicleucel).

                            Brand Name : Abecma

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : $5.0 million

                            January 30, 2024

                            Lead Product(s) : Idecabtagene Vicleucel

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved

                            Sponsor : Regeneron Pharmaceuticals

                            Deal Size : Undisclosed

                            Deal Type : Acquisition

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                            05

                            2Seventy Bio

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                            2Seventy Bio

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                            Lead Product(s) : Idecabtagene Vicleucel

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Recipient : Bristol Myers Squibb

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Abecma Delivers Sustained Progression-Free Survival Versus Standard Regimens in Earlier Lines of Therapy for R...

                            Details : Abecma (idecabtagene vicleucel) is a BCMA directed CAR-T cell immunotherapy, for patients with relapsed or refractory multiple myeloma (RRMM) who have received at least two prior therapies, including an immunomodulatory agent, a proteasome inhibitor, and...

                            Brand Name : Abecma

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            December 11, 2023

                            Lead Product(s) : Idecabtagene Vicleucel

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Recipient : Bristol Myers Squibb

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            06

                            2Seventy Bio

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                            Lead Product(s) : Idecabtagene Vicleucel

                            Therapeutic Area : Oncology

                            Study Phase : Approved

                            Recipient : Bristol Myers Squibb

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Bristol Myers Squibb and 2seventy bio Provide Update on U.S. FDA Review of sBLA for Abecma (idecabtagene vicle...

                            Details : Abecma (idecabtagene vicleucel) is a CAR T cell therapy that recognizes and binds to BCMA on the surface of multiple myeloma cells, for earlier lines of triple-class exposed relapsed or refractory multiple myeloma (RRMM).

                            Brand Name : Abecma

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            November 20, 2023

                            Lead Product(s) : Idecabtagene Vicleucel

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved

                            Recipient : Bristol Myers Squibb

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            07

                            2Seventy Bio

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                            Lead Product(s) : SC-DARIC33

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            2seventy bio Announces Clinical Study Pause of PLAT-08 Trial of SC-DARIC33 in Acute Myeloid Leukemia

                            Details : SC-DARIC33 is a investigational drug-regulated CAR T cell (DARIC) Therapy and T cells activater, which is investigated for the treatment for Acute Myeloid Leukemia.

                            Brand Name : SC-DARIC33

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            June 14, 2023

                            Lead Product(s) : SC-DARIC33

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            08

                            2Seventy Bio

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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Genetic Disease

                            Study Phase : Undisclosed

                            Sponsor : Novo Nordisk

                            Deal Size : $40.0 million

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            2seventy bio and Novo Nordisk Collaboration Delivers Key Proof of Concept Data, Triggering $15 Million Preclin...

                            Details : The collaboration is focused on an in vivo gene editing treatment for hemophilia A by utilizing 2seventy bio’s megaTAL technology that has the potential to provide a highly specific and efficient way to silence, edit, or insert genetic components.

                            Brand Name : Undisclosed

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : $5.0 million

                            May 01, 2023

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Undisclosed

                            Sponsor : Novo Nordisk

                            Deal Size : $40.0 million

                            Deal Type : Collaboration

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                            09

                            2Seventy Bio

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                            Lead Product(s) : Idecabtagene Vicleucel

                            Therapeutic Area : Oncology

                            Study Phase : Approved

                            Recipient : Bristol Myers Squibb

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Regulatory Applications Accepted Across Three Regions Globally for Abecma for Earlier Use in Adults with Tripl...

                            Details : Abecma (idecabtagene vicleucel) is the first-in-class B-cell maturation antigen (BCMA)-directed CAR T cell immunotherapy approved by the FDA for the treatment of adult patients with relapsed or refractory multiple myeloma after four or more prior lines o...

                            Brand Name : Abecma

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            April 17, 2023

                            Lead Product(s) : Idecabtagene Vicleucel

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved

                            Recipient : Bristol Myers Squibb

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            10

                            2Seventy Bio

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                            Lead Product(s) : Idecabtagene Vicleucel

                            Therapeutic Area : Oncology

                            Study Phase : Approved

                            Sponsor : Goldman Sachs

                            Deal Size : $125.0 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            2Seventy Bio Announces Pricing of Upsized Public Offering of Common Stock

                            Details : The net proceeds will be used for the advancement of the KarMMa trials to support the use of Abecma (idecabtagene vicleucel) in earlier lines of therapy and commercial activities in support of Abecma.

                            Brand Name : Abecma

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            February 28, 2023

                            Lead Product(s) : Idecabtagene Vicleucel

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved

                            Sponsor : Goldman Sachs

                            Deal Size : $125.0 million

                            Deal Type : Public Offering

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