Lead Product(s) : 3-(5,7-difluoro-4-oxo-1H-quinolin-2-yl)-4-methylsulfonylbenzonitrile
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : FX-909 is a highly potent and selective inhibitor of PPARG and has demonstrated tumor eradication in preclinical animal models of urothelial cancer at low oral doses.
Brand Name : FX-909
Molecule Type : Small molecule
Upfront Cash : Not Applicable
October 19, 2023
Lead Product(s) : 3-(5,7-difluoro-4-oxo-1H-quinolin-2-yl)-4-methylsulfonylbenzonitrile
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : 3-(5,7-difluoro-4-oxo-1H-quinolin-2-yl)-4-methylsulfonylbenzonitrile
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Flare Therapeutics
Deal Size : Undisclosed
Deal Type : Partnership
Details : The collaboration focuses to accelerate precision medicine approaches across five of Flare's programs, including its lead precision oncology program, FX-909, a small molecule inhibitor targeting PPARG, into clinical trials through advanced molecular prof...
Brand Name : FX-909
Molecule Type : Small molecule
Upfront Cash : Undisclosed
April 13, 2023
Lead Product(s) : 3-(5,7-difluoro-4-oxo-1H-quinolin-2-yl)-4-methylsulfonylbenzonitrile
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Flare Therapeutics
Deal Size : Undisclosed
Deal Type : Partnership
Lead Product(s) : 3-(5,7-difluoro-4-oxo-1H-quinolin-2-yl)-4-methylsulfonylbenzonitrile
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : GordonMD Global Investments
Deal Size : $123.0 million
Deal Type : Series B Financing
Flare Therapeutics Announces Oversubscribed $123 Million Series B Financing
Details : The net proceeds will be used to support the advancement of FX-909, a first-in-class PPARG inhibitor, into the clinic in 2023, along with continued development of Flare's platform and pipeline of novel transcription factor targets in oncology.
Brand Name : FX-909
Molecule Type : Small molecule
Upfront Cash : Undisclosed
March 22, 2023
Lead Product(s) : 3-(5,7-difluoro-4-oxo-1H-quinolin-2-yl)-4-methylsulfonylbenzonitrile
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : GordonMD Global Investments
Deal Size : $123.0 million
Deal Type : Series B Financing
Lead Product(s) : 3-(5,7-difluoro-4-oxo-1H-quinolin-2-yl)-4-methylsulfonylbenzonitrile
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Flare is advancing a novel PPARG inhibitor through Investigational New Drug (IND)-enabling studies and expects to initiate its Phase 1 clinical trial for FX-909 in 2023 in individuals with locally advanced or metastatic UC.
Brand Name : FX-909
Molecule Type : Large molecule
Upfront Cash : Not Applicable
October 28, 2022
Lead Product(s) : 3-(5,7-difluoro-4-oxo-1H-quinolin-2-yl)-4-methylsulfonylbenzonitrile
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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