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    [{"orgOrder":0,"company":"VistaGen Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"U.S.A","productType":"Small molecule","year":"2020","type":"Not Applicable","leadProduct":"4-Chlorokynurenine","moa":"NMDA receptor","graph1":"Neurology","graph2":"IND Enabling","graph3":"VistaGen Therapeutics","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Capsule","sponsorNew":"VistaGen Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"5","companyTruncated":"VistaGen Therapeutics \/ Not Applicable"},{"orgOrder":0,"company":"Nuformix","sponsor":"VistaGen Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Psychiatry\/Psychology","country":"","productType":"Small molecule","year":"2020","type":"Agreement","leadProduct":"4-Chlorokynurenine","moa":"NMDA","graph1":"Psychiatry\/Psychology","graph2":"Preclinical","graph3":"Nuformix","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Psychiatry","amount2New":0,"dosageForm":"Oral","sponsorNew":"Nuformix \/ VistaGen","highestDevelopmentStatusID":"4","companyTruncated":"Nuformix \/ VistaGen"},{"orgOrder":0,"company":"VistaGen Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"","productType":"Small molecule","year":"2020","type":"Not Applicable","leadProduct":"4-Chlorokynurenine","moa":"NMDA receptor","graph1":"Neurology","graph2":"Phase II","graph3":"VistaGen Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Capsule","sponsorNew":"VistaGen Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"8","companyTruncated":"VistaGen Therapeutics \/ Not Applicable"},{"orgOrder":0,"company":"VistaGen Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"","productType":"Small molecule","year":"2022","type":"Not Applicable","leadProduct":"4-Chlorokynurenine","moa":"","graph1":"Neurology","graph2":"Phase II","graph3":"VistaGen Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Capsule","sponsorNew":"VistaGen Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"8","companyTruncated":"VistaGen Therapeutics \/ Not Applicable"},{"orgOrder":0,"company":"VistaGen Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"","productType":"Small molecule","year":"2023","type":"Not Applicable","leadProduct":"4-Chlorokynurenine","moa":"","graph1":"Neurology","graph2":"Phase I","graph3":"VistaGen Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Capsule","sponsorNew":"VistaGen Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"6","companyTruncated":"VistaGen Therapeutics \/ Not Applicable"}]

    Find Clinical Drug Pipeline Developments & Deals for 4-Chlorokynurenine

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                            01

                            VistaGen Therapeutics

                            U.S.A arrow
                            euroPLX 86 Munich
                            Not Confirmed

                            VistaGen Therapeutics

                            U.S.A arrow
                            euroPLX 86 Munich
                            Not Confirmed
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                            Lead Product(s) : 4-Chlorokynurenine

                            Therapeutic Area : Neurology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Vistagen Receives New European Patent for AV-101

                            Details : AV-101 (4-chlorokynurenine) is an oral prodrug, which is a potent and selective full antagonist of the glycine co-agonist site of the NMDAR that inhibits certain functions of the NMDAR. It has the potential to treat multiple CNS disorders.

                            Brand Name : AV-101

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            April 06, 2023

                            Lead Product(s) : 4-Chlorokynurenine

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            02

                            VistaGen Therapeutics

                            U.S.A arrow
                            euroPLX 86 Munich
                            Not Confirmed

                            VistaGen Therapeutics

                            U.S.A arrow
                            euroPLX 86 Munich
                            Not Confirmed
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                            Lead Product(s) : 4-Chlorokynurenine

                            Therapeutic Area : Neurology

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Vistagen Announces Publication in Cells Demonstrating AV-101’s Potential for Treating Levodopa-Induced Dyski...

                            Details : AV-101 (4-chlorokynurenine) is an oral prodrug of 7-chloro-kynurenic acid (7-Cl-KYNA), which is a potent and selective full antagonist of the glycine co-agonist site of the NMDA receptor (NMDAR) that inhibits certain functions of the NMDAR.

                            Brand Name : AV-101

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            November 17, 2022

                            Lead Product(s) : 4-Chlorokynurenine

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            03

                            VistaGen Therapeutics

                            U.S.A arrow
                            euroPLX 86 Munich
                            Not Confirmed

                            VistaGen Therapeutics

                            U.S.A arrow
                            euroPLX 86 Munich
                            Not Confirmed
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                            Lead Product(s) : 4-Chlorokynurenine,Probenecid

                            Therapeutic Area : Neurology

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            VistaGen Reports Positive New Data from Second Preclinical Study of AV-101 in Combination with Probenecid

                            Details : The results of this new study complement previous preclinical data demonstrating the combination's potential to substantially increase the brain concentration of AV-101's active metabolite, 7-Cl-KYN, thereby reducing, rather than blocking, NMDA receptor ...

                            Brand Name : AV-101

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            September 03, 2020

                            Lead Product(s) : 4-Chlorokynurenine,Probenecid

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            04

                            Nuformix

                            United Kingdom arrow
                            euroPLX 86 Munich
                            Not Confirmed

                            Nuformix

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                            euroPLX 86 Munich
                            Not Confirmed
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                            Lead Product(s) : 4-Chlorokynurenine,Probenecid

                            Therapeutic Area : Psychiatry/Psychology

                            Study Phase : Preclinical

                            Sponsor : VistaGen Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            VistaGen and Nuformix agree to develop cocrystalline forms of AV-101

                            Details : Under this agreement, VistaGen and Nuformix initially will apply Nuformix's proprietary technology platform to develop patentable new crystalline forms of AV-101 that may have superior delivery, an enhanced therapeutic profile and additional intellectual...

                            Brand Name : Undisclosed

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            May 27, 2020

                            Lead Product(s) : 4-Chlorokynurenine,Probenecid

                            Therapeutic Area : Psychiatry/Psychology

                            Highest Development Status : Preclinical

                            Sponsor : VistaGen Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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                            05

                            VistaGen Therapeutics

                            U.S.A arrow
                            euroPLX 86 Munich
                            Not Confirmed

                            VistaGen Therapeutics

                            U.S.A arrow
                            euroPLX 86 Munich
                            Not Confirmed
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                            Lead Product(s) : 4-Chlorokynurenine

                            Therapeutic Area : Neurology

                            Study Phase : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            VistaGen Therapeutics Receives FDA Clearance of IND for Phase 2 Clinical Study of AV-101 as a Potential Treatm...

                            Details : The FDA's IND clearance permits VistaGen to proceed with Phase 2 clinical development of AV-101 in treatment of Dyskinesia in Parkinson's Disease Patients.

                            Brand Name : AV-101

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            January 30, 2020

                            Lead Product(s) : 4-Chlorokynurenine

                            Therapeutic Area : Neurology

                            Highest Development Status : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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