[{"orgOrder":0,"company":"IDRx","sponsor":"GSK","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2025","type":"Acquisition","leadProduct":"IDRX-42","moa":"TYK","graph1":"Oncology","graph2":"Phase I","graph3":"IDRx","amount2":1.1499999999999999,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":1.1499999999999999,"dosageForm":"Oral Tablet","sponsorNew":"IDRx \/ GSK","highestDevelopmentStatusID":"6","companyTruncated":"IDRx \/ GSK"},{"orgOrder":0,"company":"IDRx","sponsor":"Andreessen Horowitz","pharmaFlowCategory":"D","therapeuticArea":"Gastroenterology","country":"U.S.A","productType":"Other Small Molecule","year":"2022","type":"Series A Financing","leadProduct":"IDRX-42","moa":"TYK","graph1":"Gastroenterology","graph2":"Phase I","graph3":"IDRx","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Gastroenterology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"IDRx \/ Andreessen Horowitz","highestDevelopmentStatusID":"6","companyTruncated":"IDRx \/ Andreessen Horowitz"},{"orgOrder":0,"company":"IDRx","sponsor":"RA Capital Management","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2024","type":"Series B Financing","leadProduct":"IDRX-42","moa":"TYK","graph1":"Oncology","graph2":"Phase I","graph3":"IDRx","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"IDRx \/ RA Capital Management","highestDevelopmentStatusID":"6","companyTruncated":"IDRx \/ RA Capital Management"},{"orgOrder":0,"company":"IDRx","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2024","type":"Inapplicable","leadProduct":"IDRX-42","moa":"TYK","graph1":"Oncology","graph2":"Phase I","graph3":"IDRx","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"IDRx \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"IDRx \/ Inapplicable"},{"orgOrder":0,"company":"IDRx","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2024","type":"Inapplicable","leadProduct":"IDRX-42","moa":"TYK","graph1":"Oncology","graph2":"Phase I","graph3":"IDRx","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"IDRx \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"IDRx \/ Inapplicable"}]

Find Clinical Drug Pipeline Developments & Deals for [4-(Methyl-1H-pyrazol-4-yl)-benzyl] -(6-[7-(3-pyrrolidin-1-yl-propoxy)-imidazo[1,2-a] pyridin-3-yl]-pyrimidin-4-yl]-amine

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                          01

                          Interphex
                          Not Confirmed
                          Interphex
                          Not Confirmed

                          Details : Through this acquisition, GSK will expand its gastrointestinal cancer portfolio with IDRX-42. IDRX-42 is a highly selective KIT TKI developed for treating gastrointestinal stromal tumors.

                          Product Name : IDRX-42

                          Product Type : Other Small Molecule

                          Upfront Cash : $1,000.0 million

                          January 13, 2025

                          Lead Product(s) : IDRX-42

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : GSK

                          Deal Size : $1,150.0 million

                          Deal Type : Acquisition

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                          02

                          BioTrinity 2025
                          Not Confirmed
                          BioTrinity 2025
                          Not Confirmed

                          Details : IDRX-42 is a novel, KIT inhibitor that has potent activity against both the key activating mutations and broad coverage of the clinically relevant resistance mutations in KIT-driven GIST.

                          Product Name : IDRX-42

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          November 14, 2024

                          Lead Product(s) : IDRX-42

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          BioTrinity 2025
                          Not Confirmed
                          BioTrinity 2025
                          Not Confirmed

                          Details : The proceeds will support the ongoing clinical trial of its lead product IDRX-42l, targeting all major categories of activating & resistance mutations in patients with KIT-mutant GIST.

                          Product Name : IDRX-42

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          July 08, 2024

                          Lead Product(s) : IDRX-42

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : RA Capital Management

                          Deal Size : $120.0 million

                          Deal Type : Series B Financing

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                          04

                          BioTrinity 2025
                          Not Confirmed
                          BioTrinity 2025
                          Not Confirmed

                          Details : IDRX-42 is a novel, KIT inhibitor that has potent activity against both the key activating mutations and broad coverage of the clinically relevant resistance mutations in KIT-driven GIST.

                          Product Name : IDRX-42

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          March 06, 2024

                          Lead Product(s) : IDRX-42

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          BioTrinity 2025
                          Not Confirmed
                          BioTrinity 2025
                          Not Confirmed

                          Details : IDRx’s pipeline includes IDRX-42 and IDRX-73, small molecule tyrosine kinase inhibitors acquired through license agreements with Merck KGaA, Darmstadt, Germany, and Blueprint Medicines, respectively.

                          Product Name : IDRX-42

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          February 08, 2022

                          Lead Product(s) : IDRX-42

                          Therapeutic Area : Gastroenterology

                          Highest Development Status : Phase I

                          Sponsor : Andreessen Horowitz

                          Deal Size : $122.0 million

                          Deal Type : Series A Financing

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