Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Vurolenatide
Therapeutic Area : Gastroenterology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : NM-002 (vurolenatide), a proprietary long-acting GLP-1 agonist for short bowel syndrome as well as an anti-GIP monoclonal antibody and plans to conduct a Phase 3 trial with vurolenatide in patients with short bowel syndrome.
Brand Name : NM-002
Molecule Type : Peptide
Upfront Cash : Not Applicable
May 30, 2023
Lead Product(s) : Vurolenatide
Therapeutic Area : Gastroenterology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : NM-136
Therapeutic Area : Nutrition and Weight Loss
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : NM-136 is a novel humanized monoclonal antibody antagonist targeting glucose-dependent insulinotropic polypeptide (GIP). Pre-clinical data has demonstrated that anti-GIP monoclonal antibodies can effectively produce weight loss in obese mice without affe...
Brand Name : NM-136
Molecule Type : Large molecule
Upfront Cash : Not Applicable
April 05, 2023
Lead Product(s) : NM-136
Therapeutic Area : Nutrition and Weight Loss
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Vurolenatide
Therapeutic Area : Gastroenterology
Study Phase : Phase II
Sponsor : H.C. Wainwright & Co.
Deal Size : $5.0 million
Deal Type : Public Offering
Details : The Company intends to use the net proceeds, to support the clinical development of NM-002 (vurolenatide) for the treatment of short bowel syndrome and to fund the development of the Company's other pipeline programs.
Brand Name : NM-002
Molecule Type : Peptide
Upfront Cash : Undisclosed
March 15, 2023
Lead Product(s) : Vurolenatide
Therapeutic Area : Gastroenterology
Highest Development Status : Phase II
Sponsor : H.C. Wainwright & Co.
Deal Size : $5.0 million
Deal Type : Public Offering
Lead Product(s) : Vurolenatide
Therapeutic Area : Gastroenterology
Study Phase : Phase II
Sponsor : H.C. Wainwright & Co.
Deal Size : $5.0 million
Deal Type : Public Offering
Details : The Company intends to use the net proceeds, to support the clinical development of NM-002 (vurolenatide) for the treatment of short bowel syndrome and to fund the development of the Company's other pipeline programs.
Brand Name : NM-002
Molecule Type : Peptide
Upfront Cash : Undisclosed
March 14, 2023
Lead Product(s) : Vurolenatide
Therapeutic Area : Gastroenterology
Highest Development Status : Phase II
Sponsor : H.C. Wainwright & Co.
Deal Size : $5.0 million
Deal Type : Public Offering
Lead Product(s) : NM-102
Therapeutic Area : Gastroenterology
Study Phase : IND Enabling
Sponsor : Gustave Roussy
Deal Size : Undisclosed
Deal Type : Collaboration
9 Meters Biopharma Announces Continued Immuno-Oncology Collaboration with Gustave Roussy
Details : The therapeutic effect of immune checkpoint inhibitors (ICIs), such as antibodies to CTLA-4 and PD-1, might be enhanced by preventing bacterial antigens, toxins, and certain metabolites in the gut from interacting with the host immune system utilizing NM...
Brand Name : NM-102
Molecule Type : Small molecule
Upfront Cash : Undisclosed
November 14, 2022
Lead Product(s) : NM-102
Therapeutic Area : Gastroenterology
Highest Development Status : IND Enabling
Sponsor : Gustave Roussy
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : NM-136
Therapeutic Area : Nutrition and Weight Loss
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : NM-136, an anti-GIP humanized mAb, for targeted obesity disorders has demonstrated that the anti-GIP hu-mAb has a robust half-life, excellent humanness score, a high affinity for the GIP receptor.
Brand Name : NM-136
Molecule Type : Large molecule
Upfront Cash : Not Applicable
October 24, 2022
Lead Product(s) : NM-136
Therapeutic Area : Nutrition and Weight Loss
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Vurolenatide
Therapeutic Area : Gastroenterology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Vurolenatide (NM-002) 50 mg every two weeks (Q2W) dosing arm demonstrated a 30% reduction over six weeks in the primary endpoint of the Phase 2 study, mean reduction in total stool output (TSO), compared with a 32% increase for placebo - for a mean relat...
Brand Name : NM-002
Molecule Type : Peptide
Upfront Cash : Not Applicable
September 26, 2022
Lead Product(s) : Vurolenatide
Therapeutic Area : Gastroenterology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Vurolenatide
Therapeutic Area : Gastroenterology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : NM-002 (vurolenatide) is long-acting injectable GLP-1 receptor agonist that utilizes XTEN® technology to extend its circulating half-life. GLP-1, referred to "ileal brake", is hormone that slows transit of food and fluid through stomach and upper intest...
Brand Name : NM-002
Molecule Type : Peptide
Upfront Cash : Not Applicable
September 01, 2022
Lead Product(s) : Vurolenatide
Therapeutic Area : Gastroenterology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Larazotide Acetate
Therapeutic Area : Gastroenterology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : This study follows a Phase 2 clinical trial in 342 adult patients with celiac disease who had been on a gluten-free diet for at least 12 months, which concluded that INN-202 (larazotide) 0.5 mg significantly reduced symptoms of celiac disease.
Brand Name : INN-202
Molecule Type : Peptide
Upfront Cash : Not Applicable
June 21, 2022
Lead Product(s) : Larazotide Acetate
Therapeutic Area : Gastroenterology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Vurolenatide
Therapeutic Area : Gastroenterology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Vurolenatide, a novel chemical entity and long-acting injectable GLP-1 receptor agonist used to improve gastric motility. Company initiated the largest placebo-controlled Phase 2 trial in treatment of Short Bowel Syndrome.
Brand Name : NM-002
Molecule Type : Peptide
Upfront Cash : Not Applicable
October 19, 2021
Lead Product(s) : Vurolenatide
Therapeutic Area : Gastroenterology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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