Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : AVB-202
Therapeutic Area : Genetic Disease
Study Phase : Preclinical
Sponsor : Solid Biosciences
Deal Size : Undisclosed
Deal Type : Merger
Details : AVB-202 is being developed with a transgene to encode full-length frataxin protein (210 amino acids) packaged into an AAV9 capsid under the control of a promoter specifically designed to drive expression in neurons and cardiac cells.
Brand Name : AVB-202
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
December 05, 2022
Lead Product(s) : AVB-202
Therapeutic Area : Genetic Disease
Highest Development Status : Preclinical
Sponsor : Solid Biosciences
Deal Size : Undisclosed
Deal Type : Merger
Lead Product(s) : AVB-202
Therapeutic Area : Genetic Disease
Study Phase : Preclinical
Sponsor : Solid Biosciences
Deal Size : Undisclosed
Deal Type : Merger
Solid Biosciences Announces Acquisition of AavantiBio and Concurrent $75 Million Private Placement
Details : AVB-202 is being developed with a transgene to encode full-length frataxin protein (210 amino acids) packaged into an AAV9 capsid under the control of a promoter specifically designed to drive expression in neurons and cardiac cells.
Brand Name : AVB-202
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
September 30, 2022
Lead Product(s) : AVB-202
Therapeutic Area : Genetic Disease
Highest Development Status : Preclinical
Sponsor : Solid Biosciences
Deal Size : Undisclosed
Deal Type : Merger
Lead Product(s) : AAV-based Capsid
Therapeutic Area : Genetic Disease
Study Phase : Undisclosed
Sponsor : University of Florida
Deal Size : Undisclosed
Deal Type : Partnership
Details : The expansion of partnership will enable AavantiBio to further build out its platform focused on advancing innovative next generation AAV gene therapies focused on AAV’s capsid in areas of significant unmet medical need.
Brand Name : Undisclosed
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
October 12, 2021
Lead Product(s) : AAV-based Capsid
Therapeutic Area : Genetic Disease
Highest Development Status : Undisclosed
Sponsor : University of Florida
Deal Size : Undisclosed
Deal Type : Partnership
Lead Product(s) : Gene Therapy
Therapeutic Area : Genetic Disease
Study Phase : Preclinical
Recipient : Aldevron
Deal Size : Undisclosed
Deal Type : Partnership
Details : Aldevron will provide plasmids for AavantiBio’s future gene therapy programs, including the company’s neuromuscular and CNS pipeline programs.
Brand Name : Undisclosed
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
July 21, 2021
Lead Product(s) : Gene Therapy
Therapeutic Area : Genetic Disease
Highest Development Status : Preclinical
Recipient : Aldevron
Deal Size : Undisclosed
Deal Type : Partnership
Lead Product(s) : AAV-based Gene Therapy
Therapeutic Area : Genetic Disease
Study Phase : Preclinical
Recipient : Resilience
Deal Size : Undisclosed
Deal Type : Collaboration
Details : Resilience will provide process development and GMP manufacturing services including cell lines and viral banks for AavantiBio’s AVV-based therapeutic FA candidate for use in both pre-clinical studies, and Phase I/II trials in the U.S. and Europe.
Brand Name : Undisclosed
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
June 03, 2021
Lead Product(s) : AAV-based Gene Therapy
Therapeutic Area : Genetic Disease
Highest Development Status : Preclinical
Recipient : Resilience
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : AAV-based gene therapy
Therapeutic Area : Genetic Disease
Study Phase : Preclinical
Recipient : Catalent Pharma Solutions
Deal Size : Undisclosed
Deal Type : Partnership
Details : Catalent will provide process development and CGMP manufacturing of AavantiBio’s adeno-associated viral (AAV) vector-based therapeutic candidate for use in clinical trials in the U.S. and Europe.
Brand Name : Undisclosed
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
April 27, 2021
Lead Product(s) : AAV-based gene therapy
Therapeutic Area : Genetic Disease
Highest Development Status : Preclinical
Recipient : Catalent Pharma Solutions
Deal Size : Undisclosed
Deal Type : Partnership
Lead Product(s) : Gene Therapy
Therapeutic Area : Genetic Disease
Study Phase : Undisclosed
Sponsor : Sarepta Therapeutics
Deal Size : $107.0 million
Deal Type : Series A Financing
Details : AavantiBio will pursue a diversified gene therapy pipeline, including a lead program in Friedreich’s Ataxia (FA), a rare inherited genetic disease characterized by cardiac and central nervous system dysfunction.
Brand Name : Undisclosed
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
October 22, 2020
Lead Product(s) : Gene Therapy
Therapeutic Area : Genetic Disease
Highest Development Status : Undisclosed
Sponsor : Sarepta Therapeutics
Deal Size : $107.0 million
Deal Type : Series A Financing
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