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Find Clinical Drug Pipeline Developments & Deals by AavantiBio

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                          01

                          Compamed
                          Not Confirmed
                          Compamed
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                          Details : AVB-202 is being developed with a transgene to encode full-length frataxin protein (210 amino acids) packaged into an AAV9 capsid under the control of a promoter specifically designed to drive expression in neurons and cardiac cells.

                          Brand Name : AVB-202

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          December 05, 2022

                          Lead Product(s) : AVB-202

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Preclinical

                          Sponsor : Solid Biosciences

                          Deal Size : Undisclosed

                          Deal Type : Merger

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                          02

                          Compamed
                          Not Confirmed
                          Compamed
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                          Details : AVB-202 is being developed with a transgene to encode full-length frataxin protein (210 amino acids) packaged into an AAV9 capsid under the control of a promoter specifically designed to drive expression in neurons and cardiac cells.

                          Brand Name : AVB-202

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          September 30, 2022

                          Lead Product(s) : AVB-202

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Preclinical

                          Sponsor : Solid Biosciences

                          Deal Size : Undisclosed

                          Deal Type : Merger

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                          03

                          Compamed
                          Not Confirmed
                          Compamed
                          Not Confirmed

                          Details : The expansion of partnership will enable AavantiBio to further build out its platform focused on advancing innovative next generation AAV gene therapies focused on AAV’s capsid in areas of significant unmet medical need.

                          Brand Name : Undisclosed

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          October 12, 2021

                          Lead Product(s) : AAV-based Capsid

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Undisclosed

                          Sponsor : University of Florida

                          Deal Size : Undisclosed

                          Deal Type : Partnership

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                          04

                          Compamed
                          Not Confirmed
                          Compamed
                          Not Confirmed

                          Details : Aldevron will provide plasmids for AavantiBio’s future gene therapy programs, including the company’s neuromuscular and CNS pipeline programs.

                          Brand Name : Undisclosed

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          July 21, 2021

                          Lead Product(s) : Gene Therapy

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Preclinical

                          Recipient : Aldevron

                          Deal Size : Undisclosed

                          Deal Type : Partnership

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                          05

                          Compamed
                          Not Confirmed
                          Compamed
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                          Details : Resilience will provide process development and GMP manufacturing services including cell lines and viral banks for AavantiBio’s AVV-based therapeutic FA candidate for use in both pre-clinical studies, and Phase I/II trials in the U.S. and Europe.

                          Brand Name : Undisclosed

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          June 03, 2021

                          Lead Product(s) : AAV-based Gene Therapy

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Preclinical

                          Recipient : Resilience

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          06

                          Compamed
                          Not Confirmed
                          Compamed
                          Not Confirmed

                          Details : Catalent will provide process development and CGMP manufacturing of AavantiBio’s adeno-associated viral (AAV) vector-based therapeutic candidate for use in clinical trials in the U.S. and Europe.

                          Brand Name : Undisclosed

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          April 27, 2021

                          Lead Product(s) : AAV-based gene therapy

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Preclinical

                          Recipient : Catalent Pharma Solutions

                          Deal Size : Undisclosed

                          Deal Type : Partnership

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                          07

                          Compamed
                          Not Confirmed
                          Compamed
                          Not Confirmed

                          Details : AavantiBio will pursue a diversified gene therapy pipeline, including a lead program in Friedreich’s Ataxia (FA), a rare inherited genetic disease characterized by cardiac and central nervous system dysfunction.

                          Brand Name : Undisclosed

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          October 22, 2020

                          Lead Product(s) : Gene Therapy

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Undisclosed

                          Sponsor : Sarepta Therapeutics

                          Deal Size : $107.0 million

                          Deal Type : Series A Financing

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