Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : ABC008
Therapeutic Area : Immunology
Study Phase : Phase II/ Phase III
Sponsor : Redmile Group
Deal Size : $155.0 million
Deal Type : Series B Financing
Details : Abcuro will use the proceeds from the financing to complete a Phase 2/3 registrational clinical trial evaluating ABC008, a first-in-class monoclonal antibody targeting killer cell lectin like receptor G1 (KLRG1), for the treatment of inclusion body myosi...
Brand Name : ABC008
Molecule Type : Large molecule
Upfront Cash : Undisclosed
August 17, 2023
Lead Product(s) : ABC008
Therapeutic Area : Immunology
Highest Development Status : Phase II/ Phase III
Sponsor : Redmile Group
Deal Size : $155.0 million
Deal Type : Series B Financing
Lead Product(s) : ABC008
Therapeutic Area : Immunology
Study Phase : Phase II/ Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : ABC008 is a first-in-class anti-KLRG1 antibody, designed to treat diseases mediated by highly cytotoxic T cells, including the autoimmune muscle disease inclusion body myositis (IBM), T cell large granular lymphocytic leukemia (T-LGLL), and mature T cell...
Brand Name : ABC008
Molecule Type : Large molecule
Upfront Cash : Not Applicable
May 31, 2023
Lead Product(s) : ABC008
Therapeutic Area : Immunology
Highest Development Status : Phase II/ Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : ABC008
Therapeutic Area : Immunology
Study Phase : Phase II/ Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : ABC008 is a first-in-class anti-KLRG1 antibody capable of selectively depleting highly cytotoxic T cells, while sparing regulatory and central memory T cells.
Brand Name : ABC008
Molecule Type : Large molecule
Upfront Cash : Not Applicable
April 03, 2023
Lead Product(s) : ABC008
Therapeutic Area : Immunology
Highest Development Status : Phase II/ Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : ABC008
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : ABC008 is a first-in-class anti-KLRG1 antibody capable of selectively depleting highly cytotoxic T cells, while sparing regulatory and central memory T cells.
Brand Name : ABC008
Molecule Type : Large molecule
Upfront Cash : Not Applicable
October 04, 2022
Lead Product(s) : ABC008
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : ABC008
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Preliminary data also show potential improvement in disease severity of IBM in the first cohort and evidence of a dose response in the second cohort with ABC008 0.5 mg/kg for depletion of highly cytotoxic T cells.
Brand Name : ABC008
Molecule Type : Large molecule
Upfront Cash : Not Applicable
November 05, 2021
Lead Product(s) : ABC008
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : ABC008
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : ABC008 is an anti-KLRG1 antibody capable of selectively depleting subpopulations of highly cytotoxic, tissue-damaging, late-differentiated effector memory (TEM) and effector (TEMRA) T cells for treatment of inclusion body myositis (IBM), an autoimmune di...
Brand Name : ABC008
Molecule Type : Large molecule
Upfront Cash : Not Applicable
October 06, 2021
Lead Product(s) : ABC008
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : ABC008
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Mass General Brigham Ventures
Deal Size : $42.0 million
Deal Type : Series A Financing
Abcuro Raises $42 Million in Series A-1 Financing
Details : Proceeds from this financing will be used to advance ABC008, an anti-KLRG1 antibody designed to deplete cytotoxic T cells that attack healthy tissue in a variety of autoimmune diseases.
Brand Name : ABC008
Molecule Type : Large molecule
Upfront Cash : Undisclosed
January 07, 2021
Lead Product(s) : ABC008
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Mass General Brigham Ventures
Deal Size : $42.0 million
Deal Type : Series A Financing
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