Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : CER-001
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
ABIONYX Completes Successful Pre-IND Meeting with FDA for CER-001 Trial for Sepsis
Details : CER-001 is a novel recombinant human apolipoprotein A-I (apoA-I) stimulant, which is currently being evaluated for the treatment of patients with Sepsis.
Brand Name : CER-001
Molecule Type : Large molecule
Upfront Cash : Not Applicable
June 13, 2024
Lead Product(s) : CER-001
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : CER-001
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : CER-001 is a novel engineered HDL-mimetic comprised of recombinant human apoA-I and phospholipids, designed to mimic the beneficial properties of nascent pre-β HDL. It is being investigated for the treatment of septic patients at high risk of developing...
Brand Name : CER-001
Molecule Type : Large molecule
Upfront Cash : Not Applicable
January 16, 2023
Lead Product(s) : CER-001
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Human recombinant apoA-I,Sphingomyelins,Dipalmitoylphosphatidylglycerol
Therapeutic Area : Nephrology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : The results to date with CER-001 are consistent with the known pleiotropic effects of HDL, scavenging endotoxin, reversing the cytokine cascade and improving endothelial function.
Brand Name : CER-001
Molecule Type : Large molecule
Upfront Cash : Not Applicable
April 07, 2022
Lead Product(s) : Human recombinant apoA-I,Sphingomyelins,Dipalmitoylphosphatidylglycerol
Therapeutic Area : Nephrology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Human Recombinant ApoA-I,Sphingomyelins,Dipalmitoylphosphatidylglycerol
Therapeutic Area : Rare Diseases and Disorders
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : CER-001 is the first-in-class bio-HDL mimetic that directly targets a key underlying metabolic defect of LCAT deficiency. The bio-HDL is one of the most advanced biomedicines and is a potential novel treatment for kidney diseases.
Brand Name : CER-001
Molecule Type : Large molecule
Upfront Cash : Not Applicable
March 29, 2022
Lead Product(s) : Human Recombinant ApoA-I,Sphingomyelins,Dipalmitoylphosphatidylglycerol
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Human recombinant apoA-I,Sphingomyelins,Dipalmitoylphosphatidylglycerol
Therapeutic Area : Nephrology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : ABIONYX has received authorization to launch a clinical RACERS trial (a RAndomized study comparing short-term CER-001 infusions at different doses to prevent Sepsis-induced acute kidney injury) with CER-001 in septic patients at high risk of developing a...
Brand Name : CER-001
Molecule Type : Large molecule
Upfront Cash : Not Applicable
December 23, 2020
Lead Product(s) : Human recombinant apoA-I,Sphingomyelins,Dipalmitoylphosphatidylglycerol
Therapeutic Area : Nephrology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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