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Inapplicable"},{"orgOrder":0,"company":"AstraZeneca","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"UNITED KINGDOM","productType":"Other Small Molecule","year":"2024","type":"Inapplicable","leadProduct":"Capivasertib","moa":"||AKT 1\/2\/3","graph1":"Oncology","graph2":"Phase III","graph3":"AstraZeneca","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"AstraZeneca \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"AstraZeneca \/ Inapplicable"},{"orgOrder":0,"company":"Pathos","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2025","type":"Inapplicable","leadProduct":"Pocenbrodib","moa":"||CBP\/p300","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Pathos","amount2":0,"highestDevelopmentShortName":"Ph 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Find Clinical Drug Pipeline Developments & Deals for Abiraterone Acetate

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                          01

                          Lead Product(s) : Abiraterone Acetate,Prednisolone

                          Therapeutic Area : Oncology

                          Study Phase : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

                          Details : Abiraterone and the combination product Abiraterone/Prednisolone are used to treat men with prostate cancer. The 500 mg (mono product) and 500 mg + 5 mg (combination product) tablets will be marketed in Europe by our partners.

                          Product Name : Undisclosed

                          Product Type : Small molecule

                          Upfront Cash : Not Applicable

                          November 17, 2022

                          Lead Product(s) : Abiraterone Acetate,Prednisolone

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

                          Tiefenbacher Compnay Banner

                          02

                          Lead Product(s) : Abiraterone Acetate,Prednisone

                          Therapeutic Area : Oncology

                          Study Phase : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

                          Details : Abiraterone Acetate Tablets USP, 250 mg, a therapeutic equivalent generic version of Zytiga® (abiraterone acetate), is an anticancer medication. It works by preventing androgen (male hormone) production in man.

                          Product Name : Abiraterone Acetate-Generic

                          Product Type : Small molecule

                          Upfront Cash : Not Applicable

                          June 19, 2020

                          Lead Product(s) : Abiraterone Acetate,Prednisone

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

                          Dr Reddy Company Banner

                          03

                          Immuno-Oncology 360
                          Not Confirmed
                          Immuno-Oncology 360
                          Not Confirmed

                          Details : FT-7051 (pocenbrodib) is a CBP/p300 inhibitor, is being investigated as alone and in combination with abiraterone acetate, in patients with mCRPC.

                          Product Name : FT-7051

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          March 20, 2025

                          Lead Product(s) : Pocenbrodib,Abiraterone Acetate

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          Immuno-Oncology 360
                          Not Confirmed
                          Immuno-Oncology 360
                          Not Confirmed

                          Details : TLX591 (177Lu-DOTA-TLX591) is first-in-class radio-ADC investigational therapy, which is investigated for the the treatment of PSMA positive metastatic castration-resistant prostate cancer.

                          Product Name : TLX591

                          Product Type : Radiolabelled Compounds

                          Upfront Cash : Inapplicable

                          February 25, 2025

                          Lead Product(s) : Lu-177 Rosopatamab Tetraxetan,Enzalutamide,Abiraterone Acetate

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          Immuno-Oncology 360
                          Not Confirmed
                          Immuno-Oncology 360
                          Not Confirmed

                          Details : Truqap (capivasertib) is a first-in-class, potent, ATP-competitive inhibitor, is being investigated for PTEN-deficient de novo mHSPC in combination with abiraterone and ADT.

                          Product Name : Truqap

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          November 25, 2024

                          Lead Product(s) : Capivasertib,Abiraterone Acetate,Prednisone

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          Immuno-Oncology 360
                          Not Confirmed
                          Immuno-Oncology 360
                          Not Confirmed

                          Details : Lynparza (olaparib) in combination with abiraterone and prednisone or prednisolone indicated for the treatment of adult patients with BRCA-mutated metastatic castration-resistant prostate cancer.

                          Product Name : Lynparza

                          Product Type : Cytotoxic Drug

                          Upfront Cash : Inapplicable

                          September 03, 2024

                          Lead Product(s) : Olaparib,Abiraterone Acetate,Prednisone

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved FDF

                          Sponsor : Foundation Medicine

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          Immuno-Oncology 360
                          Not Confirmed
                          Immuno-Oncology 360
                          Not Confirmed

                          Details : Akeega (niraparib, abiraterone acetate) is a tablet works by inhibiting approved for BRCA-mutated mCRPC in adults. The FDA has approved FoundationOne Liquid CDx as its companion diagnostic.

                          Product Name : Akeega

                          Product Type : Cytotoxic Drug

                          Upfront Cash : Inapplicable

                          July 01, 2024

                          Lead Product(s) : Niraparib Tosylate,Abiraterone Acetate,Prednisone

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved FDF

                          Sponsor : JANSSEN BIOTECH

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          Immuno-Oncology 360
                          Not Confirmed
                          Immuno-Oncology 360
                          Not Confirmed

                          Details : KPG-121 is a modulator of the CRL4CRBN complex targeting rapid ubiquitination and degradation of CK1 alpha, IKZF3 and IKZF1. It is being investigated in combination with Abiraterone for mCRPC.

                          Product Name : KPG-121

                          Product Type : Small molecule

                          Upfront Cash : Not Applicable

                          June 05, 2024

                          Lead Product(s) : Lenalidomide Analog,Abiraterone Acetate

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          09

                          Immuno-Oncology 360
                          Not Confirmed
                          Immuno-Oncology 360
                          Not Confirmed

                          Details : Novartis obtains worldwide development & commercialization rights to ARV-766, Arvinas’ 2nd-generation PROTAC androgen receptor degrader for prostate cancer, including its preclinical AR-V7 program.

                          Product Name : ARV-766

                          Product Type : Small molecule

                          Upfront Cash : $150.0 million

                          April 11, 2024

                          Lead Product(s) : Luxdegalutamide,Abiraterone Acetate

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Novartis Pharmaceuticals Corporation

                          Deal Size : $1,160.0 million

                          Deal Type : Licensing Agreement

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                          10

                          Immuno-Oncology 360
                          Not Confirmed
                          Immuno-Oncology 360
                          Not Confirmed

                          Details : JNJ-64091742 (niraparib) is an orally administered, highly selective poly (ADP-ribose) polymerase (PARP) inhibitor that is currently being studied for the treatment of metastatic castrationresistant prostate cancer with BRCA alterations.

                          Product Name : Zejula

                          Product Type : Cytotoxic Drug

                          Upfront Cash : Inapplicable

                          October 22, 2023

                          Lead Product(s) : Niraparib Tosylate,Abiraterone Acetate,Prednisone

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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