Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Obefazimod
Therapeutic Area : Gastroenterology
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Abivax Achieves Key Milestone in Phase 3 ABTECT Trial Enrollment
Details : ABX464 (obefazimod) is an oral small molecule that was demonstrated to potentially enhance the expression of miR-124, being evaluated for moderate to severe ulcerative colitis.
Product Name : ABX464
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
January 09, 2025
Lead Product(s) : Obefazimod
Therapeutic Area : Gastroenterology
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Obefazimod
Therapeutic Area : Gastroenterology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Abivax Announces First Patient Enrolled in ENHANCE-CD Trial of Obefazimod in Crohn’s
Details : ABX464 (obefazimod) is an oral small molecule that was demonstrated to potentially enhance the expression of miR-124, being evaluated for moderate to severe crohn’s disease.
Product Name : ABX464
Product Type : Small molecule
Upfront Cash : Not Applicable
October 03, 2024
Lead Product(s) : Obefazimod
Therapeutic Area : Gastroenterology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Obefazimod
Therapeutic Area : Gastroenterology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Abivax Reports Positive Interim Efficacy Analysis of Obefazimod in Ulcerative Colitis
Details : ABX464 (obefazimod) is an oral small molecule that was demonstrated to potentially enhance the expression of miR-124, being evaluated for moderate to severe ulcerative colitis.
Product Name : ABX464
Product Type : Small molecule
Upfront Cash : Not Applicable
October 03, 2024
Lead Product(s) : Obefazimod
Therapeutic Area : Gastroenterology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Obefazimod,Etrasimod
Therapeutic Area : Gastroenterology
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Abivax Presents Preclinical Data for UC Therapy with Obefazimod and Etrasimod
Details : Abivax is actively conducting preclinical studies ABX-464 (obefazimod) in combination with Etrasimod for treating Inflammatory Bowel Disease (IBD) in the Mouse Model.
Product Name : ABX-464
Product Type : Small molecule
Upfront Cash : Not Applicable
September 25, 2024
Lead Product(s) : Obefazimod,Etrasimod
Therapeutic Area : Gastroenterology
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Obefazimod
Therapeutic Area : Gastroenterology
Study Phase : Phase III
Sponsor : Kreos Capital
Deal Size : Undisclosed
Deal Type : Financing
Abivax Secures Up to EUR 150M from Two Structured Debt Financing Transactions
Details : The proceeds are expected to be allocated mainly to the development of ABX464 (obefazimod), an oral, first-in-class, small molecule, for the treatment of adults with moderately to severely active UC and other potential chronic inflammatory indications.
Product Name : ABX464
Product Type : Small molecule
Upfront Cash : Undisclosed
August 21, 2023
Lead Product(s) : Obefazimod
Therapeutic Area : Gastroenterology
Highest Development Status : Phase III
Sponsor : Kreos Capital
Deal Size : Undisclosed
Deal Type : Financing
Lead Product(s) : Obefazimod
Therapeutic Area : Gastroenterology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : ABX464 (Obefazimod), is a highly differentiated oral drug candidate, with a novel mechanism of action based on the upregulation of a single microRNA (miR-124) with potent anti-inflammatory properties.
Product Name : ABX464
Product Type : Small molecule
Upfront Cash : Not Applicable
April 17, 2023
Lead Product(s) : Obefazimod
Therapeutic Area : Gastroenterology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Obefazimod
Therapeutic Area : Gastroenterology
Study Phase : Phase II
Sponsor : TCGX
Deal Size : $137.7 million
Deal Type : Financing
Details : The Company plans to use the net proceeds for the launch and continuation of the clinical programs of ABX464 (obefazimod), the Company's lead drug candidate in clinical development for ulcerative colitis.
Product Name : ABX464
Product Type : Small molecule
Upfront Cash : Undisclosed
February 22, 2023
Lead Product(s) : Obefazimod
Therapeutic Area : Gastroenterology
Highest Development Status : Phase II
Sponsor : TCGX
Deal Size : $137.7 million
Deal Type : Financing
Lead Product(s) : Obefazimod
Therapeutic Area : Gastroenterology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : ABX464 (Obefazimod), is a highly differentiated oral drug candidate, with a novel mechanism of action based on the upregulation of a single microRNA (miR-124) with potent anti-inflammatory properties.
Product Name : ABX464
Product Type : Small molecule
Upfront Cash : Not Applicable
February 14, 2023
Lead Product(s) : Obefazimod
Therapeutic Area : Gastroenterology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Obefazimod
Therapeutic Area : Gastroenterology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Abivax Publishes Novel Data with Respect to Obefazimod’s Anti-Inflammatory Mechanism of Action
Details : ABX464 (Obefazimod), is a highly differentiated oral drug candidate, with a novel mechanism of action based on the upregulation of a single microRNA (miR-124) with potent anti-inflammatory properties.
Product Name : ABX464
Product Type : Small molecule
Upfront Cash : Not Applicable
January 05, 2023
Lead Product(s) : Obefazimod
Therapeutic Area : Gastroenterology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Obefazimod
Therapeutic Area : Gastroenterology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Abivax Receives FDA Agreement on Pediatric Development Plan with Obefazimod in IBD
Details : The ABTECT program aims to confirm obefazimod’s potential to maintain and further improve patient-outcomes over time, as well as its safety and tolerability profile, as already observed during previously conducted Phase 2a and Phase 2b clinical trials ...
Product Name : ABX464
Product Type : Small molecule
Upfront Cash : Not Applicable
December 19, 2022
Lead Product(s) : Obefazimod
Therapeutic Area : Gastroenterology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable