Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : ABX-002
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Autobahn Gains IND Clearance for ABX-002 in Bipolar Depression Treatment
Details : ABX-002 is a highly potent, oral, thyroid hormone beta receptor (TRβ) selective agonist, which is being evaluated for the treatment of bipolar depression.
Brand Name : ABX-002
Molecule Type : Small molecule
Upfront Cash : Not Applicable
October 22, 2024
Lead Product(s) : ABX-002
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : ABX-002
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Autobahn Initiates AMPLIFY Phase 2 Trial of ABX-002 for Major Depressive Disorder
Details : ABX-002 is a highly potent, oral, thyroid hormone beta receptor (TRβ) selective agonist, which is being evaluated for the treatment of major depressive disorder as an adjunctive treatment.
Brand Name : ABX-002
Molecule Type : Small molecule
Upfront Cash : Not Applicable
September 16, 2024
Lead Product(s) : ABX-002
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : ABX-002
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase I
Sponsor : Canaan Partners
Deal Size : $100.0 million
Deal Type : Series C Financing
Autobahn Therapeutics Completes $100M Series C Financing to Advance Depression Therapies
Details : The proceeds from the financing will be used to commence mid-stage trials for the company’s lead program, ABX-002 (methyl amide prodrug), a potent and selective thyroid hormone beta receptor agonist.
Brand Name : ABX-002
Molecule Type : Small molecule
Upfront Cash : Undisclosed
July 24, 2024
Lead Product(s) : ABX-002
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase I
Sponsor : Canaan Partners
Deal Size : $100.0 million
Deal Type : Series C Financing
Lead Product(s) : ABX-002
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase I
Sponsor : ARCH Venture Partners
Deal Size : $100.0 million
Deal Type : Series C Financing
Autobahn Therapeutics Completes $100M Series C Financing to Advance Depression Therapies
Details : The proceeds will commence two Phase 2 trials for the company’s lead program, ABX-002, a potent and selective thyroid hormone beta receptor agonist for depression and other CNS disorders.
Brand Name : ABX-002
Molecule Type : Small molecule
Upfront Cash : Undisclosed
July 24, 2024
Lead Product(s) : ABX-002
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase I
Sponsor : ARCH Venture Partners
Deal Size : $100.0 million
Deal Type : Series C Financing
Lead Product(s) : ABX-002
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase I
Sponsor : Newpath Partners
Deal Size : $100.0 million
Deal Type : Series C Financing
Autobahn Therapeutics Raises 100M in Series C For CNS Drug Pipeline
Details : The proceeds will be used to commence two Phase 2 trials for company’s ABX-002, a potent and selective thyroid hormone beta receptor agonist, for MDD and bipolar disorder depression.
Brand Name : ABX-002
Molecule Type : Small molecule
Upfront Cash : Undisclosed
July 24, 2024
Lead Product(s) : ABX-002
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase I
Sponsor : Newpath Partners
Deal Size : $100.0 million
Deal Type : Series C Financing
Lead Product(s) : ABX-002
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : ABX-002 is a novel, orally administered, potent, and selective thyroid hormone beta agonist, which is investigated for the treatment of major depressive disorder.
Brand Name : ABX-002
Molecule Type : Small molecule
Upfront Cash : Not Applicable
September 11, 2023
Lead Product(s) : ABX-002
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : ABX-002
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : ABX-002 is an orally administered, potent, selective thyroid hormone beta (TRβ) agonist that is brain enhanced, demonstrates target engagement in brain regions associated with depression.
Brand Name : ABX-002
Molecule Type : Small molecule
Upfront Cash : Not Applicable
April 18, 2023
Lead Product(s) : ABX-002
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : ABX-002
Therapeutic Area : Genetic Disease
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Administration of ABX-002 resulted in potent and on-target responses in preclinical models of AMN and support company's continued advancement of ABX-002 toward clinical evaluation for the treatment of people with this rare and very difficult disease.
Brand Name : ABX-002
Molecule Type : Small molecule
Upfront Cash : Not Applicable
April 17, 2021
Lead Product(s) : ABX-002
Therapeutic Area : Genetic Disease
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : ABX-002
Therapeutic Area : Genetic Disease
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Autobahn Therapeutics Completes Successful Pre-IND Meeting with FDA
Details : Autobahn has gained alignment with FDA on the initial Phase 1a/b clinical trial protocol for ABX-002 as a monotherapy treatment for a rare neurological disorder, adrenomyeloneuropathy (AMN).
Brand Name : ABX-002
Molecule Type : Small molecule
Upfront Cash : Not Applicable
December 01, 2020
Lead Product(s) : ABX-002
Therapeutic Area : Genetic Disease
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : ABX-002
Therapeutic Area : Neurology
Study Phase : Undisclosed
Sponsor : ARCH Venture Partners
Deal Size : $76.0 million
Deal Type : Series B Financing
Details : Proceeds will be used to advance Autobahn’s lead program candidate, ABX-002, a thyroid hormone receptor beta agonist therapy for the treatment of multiple sclerosis (MS) and adrenomyeloneuropathy (AMN).
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Undisclosed
June 09, 2020
Lead Product(s) : ABX-002
Therapeutic Area : Neurology
Highest Development Status : Undisclosed
Sponsor : ARCH Venture Partners
Deal Size : $76.0 million
Deal Type : Series B Financing
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