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    [{"orgOrder":0,"company":"Actimed Therapeutics","sponsor":"Actimed Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"GERMANY","productType":"Small molecule","year":"2020","type":"Licensing Agreement","leadProduct":"Oxprenolol","moa":"Adrenergic beta-1 receptor","graph1":"Neurology","graph2":"Preclinical","graph3":"Actimed Therapeutics","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"","sponsorNew":"Actimed Therapeutics \/ Actimed Therapeutics","highestDevelopmentStatusID":"4","companyTruncated":"Actimed Therapeutics \/ Actimed Therapeutics"},{"orgOrder":0,"company":"Actimed Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Nutrition and Weight Loss","country":"UNITED KINGDOM","productType":"Small molecule","year":"2020","type":"Not Applicable","leadProduct":"Oxprenolol","moa":"Adrenergic beta-1 receptor","graph1":"Nutrition and Weight 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    Find Clinical Drug Pipeline Developments & Deals by Actimed Therapeutics

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                            01

                            Actimed Therapeutics

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                            Lead Product(s) : Oxprenolol

                            Therapeutic Area : Neurology

                            Study Phase : Preclinical

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Actimed Therapeutics Granted FDA Orphan Drug Status for ALS Treatment ACM-002

                            Details : ACM-002 (S-oxprenolol) has demonstrated slowing disease progression, improvement in survival, attenuation of muscle loss, motor neuron protection in amyotrophic lateral sclerosis (ALS).

                            Brand Name : ACM-002

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            September 04, 2024

                            Lead Product(s) : Oxprenolol

                            Therapeutic Area : Neurology

                            Highest Development Status : Preclinical

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            02

                            Actimed Therapeutics

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                            Lead Product(s) : S-pindolol Benzoate

                            Therapeutic Area : Oncology

                            Study Phase : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Actimed Therapeutics Announces FDA Approval of its Investigational New Drug Application for Phase 2b/3 IMPACT ...

                            Details : ACM-001.1 (S-pindolol benzoate) targets multiple pathways that drive cachexia and has generated promising proof of concept Phase 2/3 clinical data in cachexia associated with colorectal cancer (IMPACT CRC) and another in patients with non-small cell lung...

                            Brand Name : ACM-001.1

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            September 07, 2023

                            Lead Product(s) : S-pindolol Benzoate

                            Therapeutic Area : Oncology

                            Highest Development Status : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            03

                            Actimed Therapeutics

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                            Lead Product(s) : S-pindolol Benzoate

                            Therapeutic Area : Nutrition and Weight Loss

                            Study Phase : Phase II

                            Sponsor : Mankind Pharma

                            Deal Size : $6.3 million

                            Deal Type : Series A Financing

                            DEALS_DEV arrow-down

                            Actimed Therapeutics Closes Over-Subscribed Series A Financing Round of £5 Million to Advance Clinical Develo...

                            Details : The investment will support the development of the Actimed pipeline, including ACM-001.1 (S-pindolol benzoate), with preparations under way for a Phase 2b/3 programme targeted at the treatment of cancer cachexia in non-small cell lung cancer and colorect...

                            Brand Name : ACM-001.1

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            June 26, 2023

                            Lead Product(s) : S-pindolol Benzoate

                            Therapeutic Area : Nutrition and Weight Loss

                            Highest Development Status : Phase II

                            Sponsor : Mankind Pharma

                            Deal Size : $6.3 million

                            Deal Type : Series A Financing

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                            04

                            Actimed Therapeutics

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                            Lead Product(s) : Pindolol

                            Therapeutic Area : Nutrition and Weight Loss

                            Study Phase : Phase II

                            Sponsor : Mankind Pharma

                            Deal Size : $12.1 million

                            Deal Type : Financing

                            DEALS_DEV arrow-down

                            Actimed Therapeutics Successfully Closes Second Tranche Of £10m Seed Financing To Progress Pipeline For Treat...

                            Details : ACM-001.1 (S-pindolol benzoate) targets multiple pathways that drive cachexia and has generated promising proof of concept Phase 2a clinical data in cachexia patients.

                            Brand Name : ACM-001.1

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            January 04, 2023

                            Lead Product(s) : Pindolol

                            Therapeutic Area : Nutrition and Weight Loss

                            Highest Development Status : Phase II

                            Sponsor : Mankind Pharma

                            Deal Size : $12.1 million

                            Deal Type : Financing

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                            05

                            Actimed Therapeutics

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                            Lead Product(s) : Pindolol

                            Therapeutic Area : Musculoskeletal

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Actimed Therapeutics Continues to Strengthen Intellectual Property Portfolio with Newly Granted US and Canadia...

                            Details : S-oxprenolol is the second in a new class of anabolic-catabolic transforming agents (ACTAs) under development by Actimed and this newest patent completes the global patent estate relating to the treatment of ALS with S-oxprenolol.

                            Brand Name : ACM-001

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            October 13, 2021

                            Lead Product(s) : Pindolol

                            Therapeutic Area : Musculoskeletal

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            06

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                            Lead Product(s) : Pindolol

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : $3.4 million

                            Deal Type : Series B Financing

                            DEALS_DEV arrow-down

                            Actimed Therapeutics Successfully Closed of £2.5m Extended Seed B Funding Round

                            Details : The proceeds will allow Actimed to further advance the development of its lead compound, S-pindolol (ACM-001.1), for cancer cachexia, by performing a Pharmacokinetic (PK) and Pharmacodynamic (PD) study due to start later this year.

                            Brand Name : ACM-001

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            June 10, 2021

                            Lead Product(s) : Pindolol

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : $3.4 million

                            Deal Type : Series B Financing

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                            07

                            Actimed Therapeutics

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                            Actimed Therapeutics

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                            Lead Product(s) : Oxprenolol

                            Therapeutic Area : Nutrition and Weight Loss

                            Study Phase : Preclinical

                            Sponsor : Faraday Pharmaceuticals

                            Deal Size : $134.7 million

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Actimed Therapeutics and Faraday Pharmaceuticals Announce License Agreement for S-oxprenolol

                            Details : Faraday gains global rights to develop and commercialize S-oxprenolol for cancer cachexia and any other indications outside of amyotrophic lateral sclerosis (ALS).

                            Brand Name : ACM-002

                            Molecule Type : Small molecule

                            Upfront Cash : $2.7 million

                            April 13, 2021

                            Lead Product(s) : Oxprenolol

                            Therapeutic Area : Nutrition and Weight Loss

                            Highest Development Status : Preclinical

                            Sponsor : Faraday Pharmaceuticals

                            Deal Size : $134.7 million

                            Deal Type : Licensing Agreement

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                            08

                            Actimed Therapeutics

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                            Lead Product(s) : Oxprenolol

                            Therapeutic Area : Nutrition and Weight Loss

                            Study Phase : Preclinical

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Actimed Therapeutics Granted Broad US Patent Covering Rights to ACM–002 (S-oxprenolol) for Treating Cancer C...

                            Details : ACM-002 (S-oxprenolol) is the second in a new class of anabolic-catabolic transforming agents (ACTAs) under development by Actimed. The new patent contains claims which cover the treatment of the symptoms of cachexia in patients having a late stage cance...

                            Brand Name : ACM-002

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            December 01, 2020

                            Lead Product(s) : Oxprenolol

                            Therapeutic Area : Nutrition and Weight Loss

                            Highest Development Status : Preclinical

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            09

                            Actimed Therapeutics

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                            Actimed Therapeutics

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                            Lead Product(s) : Oxprenolol

                            Therapeutic Area : Neurology

                            Study Phase : Preclinical

                            Recipient : Charité Universitätsmedizin

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Actimed Therapeutics Licenses Additional European Patent Rights to S-oxprenolol in ALS from Charité - Univers...

                            Details : Actimed Therapeutics has licensed additional European patent rights to S-oxprenolol in amyotrophic lateral sclerosis (ALS) from Charité – Universitätsmedizin Berlin (Charité). This gives Actimed global rights in this indication.

                            Brand Name : ACM-002

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            November 23, 2020

                            Lead Product(s) : Oxprenolol

                            Therapeutic Area : Neurology

                            Highest Development Status : Preclinical

                            Recipient : Charité Universitätsmedizin

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

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