Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Oxprenolol
Therapeutic Area : Neurology
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Actimed Therapeutics Granted FDA Orphan Drug Status for ALS Treatment ACM-002
Details : ACM-002 (S-oxprenolol) has demonstrated slowing disease progression, improvement in survival, attenuation of muscle loss, motor neuron protection in amyotrophic lateral sclerosis (ALS).
Brand Name : ACM-002
Molecule Type : Small molecule
Upfront Cash : Not Applicable
September 04, 2024
Lead Product(s) : Oxprenolol
Therapeutic Area : Neurology
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : S-pindolol Benzoate
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : ACM-001.1 (S-pindolol benzoate) targets multiple pathways that drive cachexia and has generated promising proof of concept Phase 2/3 clinical data in cachexia associated with colorectal cancer (IMPACT CRC) and another in patients with non-small cell lung...
Brand Name : ACM-001.1
Molecule Type : Small molecule
Upfront Cash : Not Applicable
September 07, 2023
Lead Product(s) : S-pindolol Benzoate
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : S-pindolol Benzoate
Therapeutic Area : Nutrition and Weight Loss
Study Phase : Phase II
Sponsor : Mankind Pharma
Deal Size : $6.3 million
Deal Type : Series A Financing
Details : The investment will support the development of the Actimed pipeline, including ACM-001.1 (S-pindolol benzoate), with preparations under way for a Phase 2b/3 programme targeted at the treatment of cancer cachexia in non-small cell lung cancer and colorect...
Brand Name : ACM-001.1
Molecule Type : Small molecule
Upfront Cash : Undisclosed
June 26, 2023
Lead Product(s) : S-pindolol Benzoate
Therapeutic Area : Nutrition and Weight Loss
Highest Development Status : Phase II
Sponsor : Mankind Pharma
Deal Size : $6.3 million
Deal Type : Series A Financing
Lead Product(s) : Pindolol
Therapeutic Area : Nutrition and Weight Loss
Study Phase : Phase II
Sponsor : Mankind Pharma
Deal Size : $12.1 million
Deal Type : Financing
Details : ACM-001.1 (S-pindolol benzoate) targets multiple pathways that drive cachexia and has generated promising proof of concept Phase 2a clinical data in cachexia patients.
Brand Name : ACM-001.1
Molecule Type : Small molecule
Upfront Cash : Undisclosed
January 04, 2023
Lead Product(s) : Pindolol
Therapeutic Area : Nutrition and Weight Loss
Highest Development Status : Phase II
Sponsor : Mankind Pharma
Deal Size : $12.1 million
Deal Type : Financing
Lead Product(s) : Pindolol
Therapeutic Area : Musculoskeletal
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : S-oxprenolol is the second in a new class of anabolic-catabolic transforming agents (ACTAs) under development by Actimed and this newest patent completes the global patent estate relating to the treatment of ALS with S-oxprenolol.
Brand Name : ACM-001
Molecule Type : Small molecule
Upfront Cash : Not Applicable
October 13, 2021
Lead Product(s) : Pindolol
Therapeutic Area : Musculoskeletal
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Actimed Therapeutics Successfully Closed of £2.5m Extended Seed B Funding Round
Details : The proceeds will allow Actimed to further advance the development of its lead compound, S-pindolol (ACM-001.1), for cancer cachexia, by performing a Pharmacokinetic (PK) and Pharmacodynamic (PD) study due to start later this year.
Brand Name : ACM-001
Molecule Type : Small molecule
Upfront Cash : Undisclosed
June 10, 2021
Lead Product(s) : Oxprenolol
Therapeutic Area : Nutrition and Weight Loss
Study Phase : Preclinical
Sponsor : Faraday Pharmaceuticals
Deal Size : $134.7 million
Deal Type : Licensing Agreement
Actimed Therapeutics and Faraday Pharmaceuticals Announce License Agreement for S-oxprenolol
Details : Faraday gains global rights to develop and commercialize S-oxprenolol for cancer cachexia and any other indications outside of amyotrophic lateral sclerosis (ALS).
Brand Name : ACM-002
Molecule Type : Small molecule
Upfront Cash : $2.7 million
April 13, 2021
Lead Product(s) : Oxprenolol
Therapeutic Area : Nutrition and Weight Loss
Highest Development Status : Preclinical
Sponsor : Faraday Pharmaceuticals
Deal Size : $134.7 million
Deal Type : Licensing Agreement
Lead Product(s) : Oxprenolol
Therapeutic Area : Nutrition and Weight Loss
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : ACM-002 (S-oxprenolol) is the second in a new class of anabolic-catabolic transforming agents (ACTAs) under development by Actimed. The new patent contains claims which cover the treatment of the symptoms of cachexia in patients having a late stage cance...
Brand Name : ACM-002
Molecule Type : Small molecule
Upfront Cash : Not Applicable
December 01, 2020
Lead Product(s) : Oxprenolol
Therapeutic Area : Nutrition and Weight Loss
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Oxprenolol
Therapeutic Area : Neurology
Study Phase : Preclinical
Recipient : Charité Universitätsmedizin
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Details : Actimed Therapeutics has licensed additional European patent rights to S-oxprenolol in amyotrophic lateral sclerosis (ALS) from Charité – Universitätsmedizin Berlin (Charité). This gives Actimed global rights in this indication.
Brand Name : ACM-002
Molecule Type : Small molecule
Upfront Cash : Undisclosed
November 23, 2020
Lead Product(s) : Oxprenolol
Therapeutic Area : Neurology
Highest Development Status : Preclinical
Recipient : Charité Universitätsmedizin
Deal Size : Undisclosed
Deal Type : Licensing Agreement
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