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Under the terms of the agreement, Takeda will receive an exclusive, worldwide license to AcuraStem's PIKFYVE targeted therapeutics including AS-202, an innovative antisense oligonucleotide (ASO) for the treatment of Amyotrophic Lateral Sclerosis (ALS).
Lead Product(s): AS-202
Therapeutic Area: Neurology Product Name: AS-202
Highest Development Status: IND Enabling Product Type: Large molecule
Partner/Sponsor/Collaborator: Takeda Pharmaceutical
Deal Size: $580.0 million Upfront Cash: Undisclosed
Deal Type: Licensing Agreement September 25, 2023
Details:
The CDMRP award nomination underscores the significance of AcuraStem’s drug candidate AS-202. AcuraStem’s most advanced therapeutic candidate, AS-202, lowers levels of the lipid kinase PIKFYVE.
Lead Product(s): AS-202
Therapeutic Area: Neurology Product Name: AS-202
Highest Development Status: IND Enabling Product Type: Small molecule
Partner/Sponsor/Collaborator: U.S Department of Defense
Deal Size: $1.0 million Upfront Cash: Undisclosed
Deal Type: Funding May 25, 2021