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Find Clinical Drug Pipeline Developments & Deals by Adamas Pharmaceuticals

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                          Top Deals by Deal Size (USD bn)

                          01

                          MAGHREB PHARMA
                          Not Confirmed
                          MAGHREB PHARMA
                          Not Confirmed

                          Details : Acquistion will strengthens Parkinson’s disease portfolio with GOCOVRI (amantadine) extended release capsules, the first and only FDA-approved medicine indicated for the treatment of both OFF and dyskinesia in patients with Parkinson’s disease receiv...

                          Product Name : Gocovri

                          Product Type : Other Small Molecule

                          Upfront Cash : $450.0 million

                          November 24, 2021

                          Lead Product(s) : Amantadine Hydrochloride

                          Therapeutic Area : Neurology

                          Highest Development Status : Approved FDF

                          Sponsor : Supernus Pharmaceuticals

                          Deal Size : $450.0 million

                          Deal Type : Acquisition

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                          02

                          MAGHREB PHARMA
                          Not Confirmed
                          MAGHREB PHARMA
                          Not Confirmed

                          Details : The transaction will provide Supernus with two marketed products: GOCOVRI (amantadine) extended release capsules, indicated for both OFF and dyskinesia in patients with Parkinson’s disease and Osmolex ER (amantadine) tablets, approved for Parkinson’s...

                          Product Name : Gocovri

                          Product Type : Other Small Molecule

                          Upfront Cash : $450.0 million

                          November 10, 2021

                          Lead Product(s) : Amantadine Hydrochloride

                          Therapeutic Area : Neurology

                          Highest Development Status : Approved FDF

                          Sponsor : Supernus Pharmaceuticals

                          Deal Size : $450.0 million

                          Deal Type : Acquisition

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                          03

                          MAGHREB PHARMA
                          Not Confirmed
                          MAGHREB PHARMA
                          Not Confirmed

                          Details : At week 12, participants treated with GOCOVRI reported statistically significant improvements in motor control for daily activities compared to placebo (least-squares mean changes from baseline of –3.4 points for GOCOVRI and –1.4 for placebo).

                          Product Name : Gocovri

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          October 06, 2021

                          Lead Product(s) : Amantadine Hydrochloride

                          Therapeutic Area : Neurology

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          MAGHREB PHARMA
                          Not Confirmed
                          MAGHREB PHARMA
                          Not Confirmed

                          Details : Patients enrolled in the pivotal trials increased daily ON time without dyskinesia by 2.9 hours with GOCOVRI compared to placebo, through the reduction of both OFF time and dyskinesia.

                          Product Name : Gocovri

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          March 29, 2021

                          Lead Product(s) : Amantadine Hydrochloride

                          Therapeutic Area : Neurology

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          Cophex
                          Not Confirmed
                          Cophex
                          Not Confirmed

                          Details : Adamas has proposed to include GOCOVRI as an appropriate therapy for the treatment of OFF episodes in PD patients receiving levodopa. The clinical evidence supporting GOCOVRI’s effect on OFF time was demonstrated in two large pivotal Phase 3 trials.

                          Product Name : Gocovri

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          April 06, 2020

                          Lead Product(s) : Amantadine Hydrochloride

                          Therapeutic Area : Neurology

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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