Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : BX004
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I/ Phase II
Sponsor : BiomX
Deal Size : Undisclosed
Deal Type : Merger
BiomX Closes Acquisition Of Adaptive Phage Therapeutics with $50 Million Financing
Details : The combined company will advance its pipeline with two Phase 2 assets, BX004 for chronic pulmonary infections in cystic fibrosis patients, and BX211 for diabetic foot osteomyelitis.
Brand Name : BX004
Molecule Type : Large molecule
Upfront Cash : Undisclosed
March 18, 2024
Lead Product(s) : BX004
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I/ Phase II
Sponsor : BiomX
Deal Size : Undisclosed
Deal Type : Merger
Lead Product(s) : BX004
Therapeutic Area : Genetic Disease
Study Phase : Phase I/ Phase II
Sponsor : BiomX
Deal Size : Undisclosed
Deal Type : Merger
BiomX Announces Entry into Merger Agreement with Adaptive and $50 Million Financing
Details : The combined company will advance its pipeline with two Phase 2 assets, BX004 for chronic pulmonary infections in cystic fibrosis patients, and BX211 for diabetic foot osteomyelitis.
Brand Name : BX004
Molecule Type : Large molecule
Upfront Cash : Undisclosed
March 06, 2024
Lead Product(s) : BX004
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I/ Phase II
Sponsor : BiomX
Deal Size : Undisclosed
Deal Type : Merger
Lead Product(s) : Bacteriophage-based Therapy
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Sponsor : Deerfield Management
Deal Size : $24.0 million
Deal Type : Series B Financing
Details : The financing will be used in continuing clinical progression of APT’s pipeline of bacteriophage-based therapies that specifically target and kill bacteria, to create personalized treatments for patients with difficult-to-treat AMR infections.
Brand Name : Undisclosed
Molecule Type : Large molecule
Upfront Cash : $12.0 million
June 13, 2023
Lead Product(s) : Bacteriophage-based Therapy
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Sponsor : Deerfield Management
Deal Size : $24.0 million
Deal Type : Series B Financing
Lead Product(s) : Bacteriophage-based Therapy
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Undisclosed
Sponsor : Israeli Phage Therapy Center
Deal Size : Undisclosed
Deal Type : Collaboration
Details : Under the agreement, Hadasit and Yissum grants APT exclusive rights to make, use, and sell licensed phages for human bacteriophage-based therapy, with the right to sublicense through multiple tiers.
Brand Name : Undisclosed
Molecule Type : Large molecule
Upfront Cash : Undisclosed
May 24, 2023
Lead Product(s) : Bacteriophage-based Therapy
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Undisclosed
Sponsor : Israeli Phage Therapy Center
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : WRAIR_EPa11,WRAIR_EPa39,WRAIR_EPa83
Therapeutic Area : Genetic Disease
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : The investigational phage therapeutic, WRAIR-PAM-CF1, was developed by the Walter Reed Army Institute of Research (WRAIR) and is licensed to and manufactured by APT. The trial is expected to enroll a total of 72 patients at multiple sites across the coun...
Brand Name : WRAIR_PAM-CF1
Molecule Type : Large molecule
Upfront Cash : Not Applicable
January 12, 2023
Lead Product(s) : WRAIR_EPa11,WRAIR_EPa39,WRAIR_EPa83
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Phage-based Therapy
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Phages from the APT phage bank (Phage-based Therapy) are precision-matched to the patient’s infections through a proprietary phage susceptibility test (PST) that APT has teamed with Mayo Clinic Laboratories to commercialize on a global scale.
Brand Name : PhageBank
Molecule Type : Large molecule
Upfront Cash : Not Applicable
May 17, 2022
Lead Product(s) : Phage-based Therapy
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Phage Therapy,Antibiotic
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I/ Phase II
Sponsor : Deerfield Management
Deal Size : $61.0 million
Deal Type : Series B Financing
Adaptive Phage Therapeutics Extends Series B to $61 million with Addition of The AMR Action Fund
Details : Proceeds of the AMR Action Fund’s investment are primarily intended to support APT’s clinical trials to address substantial unmet patient needs in Prosthetic Joint Infection (PJI) and Diabetic Foot Osteomyelitis (DFO).
Brand Name : Undisclosed
Molecule Type : Large molecule
Upfront Cash : Undisclosed
April 04, 2022
Lead Product(s) : Phage Therapy,Antibiotic
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I/ Phase II
Sponsor : Deerfield Management
Deal Size : $61.0 million
Deal Type : Series B Financing
Lead Product(s) : Bacteriophage Therapies
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I/ Phase II
Sponsor : U.S. Department of Defense
Deal Size : $31.2 million
Deal Type : Funding
Details : Funding will support the PhageBank™ platform to treat drug-resistant infections across multiple indications which leverages an ever-expanding library of bacteriophage (phage) that collectively provide evergreen broad spectrum and polymicrobial coverage...
Brand Name : PhageBank
Molecule Type : Large molecule
Upfront Cash : Undisclosed
September 30, 2021
Lead Product(s) : Bacteriophage Therapies
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I/ Phase II
Sponsor : U.S. Department of Defense
Deal Size : $31.2 million
Deal Type : Funding
Lead Product(s) : Phage-based Therapy
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : In-vitro activity of multiple phage strain candidates were assessed by means of APT’s PhageBank™ Susceptibility Test (PST) to determine the clinically relevant selection.
Brand Name : PhageBank
Molecule Type : Large molecule
Upfront Cash : Not Applicable
September 09, 2021
Lead Product(s) : Phage-based Therapy
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Phage Therapy,Antibiotics
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I/ Phase II
Sponsor : Deerfield Management
Deal Size : $40.8 million
Deal Type : Series B Financing
Adaptive Phage Therapeutics Announces $40.75 Million Series B Financing
Details : APT’s PhageBank™ technology is a growing collection of hundreds of bacteriophage, collectively providing broad spectrum coverage against six of the highest priority multi-drug resistant bacterial pathogens.
Brand Name : Undisclosed
Molecule Type : Large molecule
Upfront Cash : Undisclosed
May 11, 2021
Lead Product(s) : Phage Therapy,Antibiotics
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I/ Phase II
Sponsor : Deerfield Management
Deal Size : $40.8 million
Deal Type : Series B Financing
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