Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : siRNA Duplex Oligonucleotide
Therapeutic Area : Genetic Disease
Study Phase : Phase I
Sponsor : Bain Capital Life Sciences
Deal Size : $200.0 million
Deal Type : Series C Financing
Details : The net proceeds will advance ADARx clinical programs including ADX-324, a siRNA designed to reduce the production of PKK, a protein critical to the etiology of hereditary angioedema, and ADX-038, under development for the treatment of paroxysmal nocturn...
Brand Name : ADX-324
Molecule Type : Large molecule
Upfront Cash : Undisclosed
August 09, 2023
Lead Product(s) : siRNA Duplex Oligonucleotide
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I
Sponsor : Bain Capital Life Sciences
Deal Size : $200.0 million
Deal Type : Series C Financing
Lead Product(s) : siRNA Duplex Oligonucleotide
Therapeutic Area : Genetic Disease
Study Phase : Phase I
Sponsor : Ascenta Capital
Deal Size : $46.0 million
Deal Type : Series B Financing
ADARx Pharmaceuticals Raises $46 Million as Lead Product Enters the Clinic
Details : The net proceeds will be used to advance ADARx’s proprietary RNA targeting platform together with novel oligonucleotide delivery technologies and to initiate phase I clinical trial of ADX-324 (siRNA duplex oligonucleotide), for the treatment of heredit...
Brand Name : ADX-324
Molecule Type : Large molecule
Upfront Cash : Undisclosed
January 20, 2023
Lead Product(s) : siRNA Duplex Oligonucleotide
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I
Sponsor : Ascenta Capital
Deal Size : $46.0 million
Deal Type : Series B Financing
Lead Product(s) : siRNA
Therapeutic Area : Genetic Disease
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
ADARx Pharmaceuticals Announces Dosing of First Cohort in Phase 1 Clinical Study of ADX-324
Details : ADX-324 is a short-interfering RNA (siRNA) designed to reduce the production of PKK, a protein critical to the etiology of HAE. HAE is a rare genetic disease that causes painful, rapid, and potentially life-threatening swelling attacks.
Brand Name : ADX-324
Molecule Type : Large molecule
Upfront Cash : Not Applicable
January 20, 2023
Lead Product(s) : siRNA
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Oligonucleotide-based Therapeutics
Therapeutic Area : Genetic Disease
Study Phase : IND Enabling
Sponsor : SR One Capital Management
Deal Size : $75.0 million
Deal Type : Series B Financing
ADARx Raises $75 Million to Advance Growing Pipeline
Details : The proceeds from the Series B financing will be used to advance ADARx’s proprietary RNA platform technologies for base editing, inhibition, degradation, and delivery.
Brand Name : Undisclosed
Molecule Type : Large molecule
Upfront Cash : Undisclosed
September 08, 2021
Lead Product(s) : Oligonucleotide-based Therapeutics
Therapeutic Area : Genetic Disease
Highest Development Status : IND Enabling
Sponsor : SR One Capital Management
Deal Size : $75.0 million
Deal Type : Series B Financing
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