[{"orgOrder":0,"company":"ADARx Pharmaceuticals","sponsor":"SR One Capital Management","pharmaFlowCategory":"D","amount":"$75.0 million","upfrontCash":"Undisclosed","newsHeadline":"ADARx Raises $75 Million to Advance Growing Pipeline","therapeuticArea":"Genetic Disease","highestDevelopmentStatus":"IND Enabling","country":"","productType":"Large molecule","productStatus":"Undisclosed","date":"September 2021","year":"2021","type":"Series B Financing","leadProduct":"Oligonucleotide-based Therapeutics","moa":"RNA","url1":"","url2":"","graph1":"Genetic Disease","graph2":"IND Enabling","graph3":"ADARx Pharmaceuticals","amount2":0.080000000000000002,"therapeuticAreaNew":"Genetic Disease","highestDevelopmentStatusNew":"IND Enabling","highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Genetic Disease","productSubType":"","amount2New":0.080000000000000002,"dosageForm":"","sponsorNew":"ADARx Pharmaceuticals \/ SR One Capital Management","highestDevelopmentStatusID":"5","companyTruncated":"ADARx Pharmaceuticals \/ SR One Capital Management"},{"orgOrder":0,"company":"ADARx Pharmaceuticals","sponsor":"Ascenta Capital","pharmaFlowCategory":"D","amount":"$46.0 million","upfrontCash":"Undisclosed","newsHeadline":"ADARx Pharmaceuticals Raises $46 Million as Lead Product Enters the Clinic","therapeuticArea":"Genetic Disease","highestDevelopmentStatus":"Phase I","country":"","productType":"Large molecule","productStatus":"New Molecular Entity","date":"January 2023","year":"2023","type":"Series B Financing","leadProduct":"siRNA Duplex Oligonucleotide","moa":"","url1":"","url2":"","graph1":"Genetic Disease","graph2":"Phase I","graph3":"ADARx Pharmaceuticals","amount2":0.050000000000000003,"therapeuticAreaNew":"Genetic Disease","highestDevelopmentStatusNew":"Phase I","highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Genetic Disease","productSubType":"","amount2New":0.050000000000000003,"dosageForm":"","sponsorNew":"ADARx Pharmaceuticals \/ Ascenta Capital","highestDevelopmentStatusID":"6","companyTruncated":"ADARx Pharmaceuticals \/ Ascenta Capital"},{"orgOrder":0,"company":"ADARx Pharmaceuticals","sponsor":"Not Applicable","pharmaFlowCategory":"DU","amount":"Not Applicable","upfrontCash":"Not Applicable","newsHeadline":"ADARx Pharmaceuticals Announces Dosing of First Cohort in Phase 1 Clinical Study of ADX-324","therapeuticArea":"Genetic Disease","highestDevelopmentStatus":"Phase I","country":"","productType":"Large molecule","productStatus":"New Molecular Entity","date":"January 2023","year":"2023","type":"Not Applicable","leadProduct":"siRNA","moa":"","url1":"","url2":"","graph1":"Genetic Disease","graph2":"Phase I","graph3":"ADARx Pharmaceuticals","amount2":0,"therapeuticAreaNew":"Genetic Disease","highestDevelopmentStatusNew":"Phase I","highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Genetic Disease","productSubType":"","amount2New":0,"dosageForm":"Injectable\/Injection","sponsorNew":"ADARx Pharmaceuticals \/ Not Applicable","highestDevelopmentStatusID":"6","companyTruncated":"ADARx Pharmaceuticals \/ Not Applicable"},{"orgOrder":0,"company":"ADARx Pharmaceuticals","sponsor":"Bain Capital Life Sciences","pharmaFlowCategory":"D","amount":"$200.0 million","upfrontCash":"Undisclosed","newsHeadline":"ADARx Pharmaceuticals, a Leader in Next Generation RNA Therapeutics, Announces Oversubscribed $200 Million Series C Financing","therapeuticArea":"Genetic Disease","highestDevelopmentStatus":"Phase I","country":"","productType":"Large molecule","productStatus":"New Molecular Entity","date":"August 2023","year":"2023","type":"Series C Financing","leadProduct":"siRNA Duplex Oligonucleotide","moa":"","url1":"","url2":"","graph1":"Genetic Disease","graph2":"Phase I","graph3":"ADARx Pharmaceuticals","amount2":0.20000000000000001,"therapeuticAreaNew":"Genetic Disease","highestDevelopmentStatusNew":"Phase I","highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Genetic Disease","productSubType":"","amount2New":0.20000000000000001,"dosageForm":"","sponsorNew":"ADARx Pharmaceuticals \/ Bain Capital Life Sciences","highestDevelopmentStatusID":"6","companyTruncated":"ADARx Pharmaceuticals \/ Bain Capital Life Sciences"}]

Find Clinical Drug Pipeline Developments & Deals by ADARx Pharmaceuticals

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          FNCE 2024
                          Not Confirmed
                          FNCE 2024
                          Not Confirmed

                          Lead Product(s) : siRNA Duplex Oligonucleotide

                          Therapeutic Area : Genetic Disease

                          Study Phase : Phase I

                          Sponsor : Bain Capital Life Sciences

                          Deal Size : $200.0 million

                          Deal Type : Series C Financing

                          Details : The net proceeds will advance ADARx clinical programs including ADX-324, a siRNA designed to reduce the production of PKK, a protein critical to the etiology of hereditary angioedema, and ADX-038, under development for the treatment of paroxysmal nocturn...

                          Brand Name : ADX-324

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          August 09, 2023

                          Lead Product(s) : siRNA Duplex Oligonucleotide

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase I

                          Sponsor : Bain Capital Life Sciences

                          Deal Size : $200.0 million

                          Deal Type : Series C Financing

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                          02

                          FNCE 2024
                          Not Confirmed
                          FNCE 2024
                          Not Confirmed

                          Details : The net proceeds will be used to advance ADARx’s proprietary RNA targeting platform together with novel oligonucleotide delivery technologies and to initiate phase I clinical trial of ADX-324 (siRNA duplex oligonucleotide), for the treatment of heredit...

                          Brand Name : ADX-324

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          January 20, 2023

                          Lead Product(s) : siRNA Duplex Oligonucleotide

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase I

                          Sponsor : Ascenta Capital

                          Deal Size : $46.0 million

                          Deal Type : Series B Financing

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                          03

                          FNCE 2024
                          Not Confirmed
                          FNCE 2024
                          Not Confirmed

                          Details : ADX-324 is a short-interfering RNA (siRNA) designed to reduce the production of PKK, a protein critical to the etiology of HAE. HAE is a rare genetic disease that causes painful, rapid, and potentially life-threatening swelling attacks.

                          Brand Name : ADX-324

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          January 20, 2023

                          Lead Product(s) : siRNA

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          04

                          FNCE 2024
                          Not Confirmed
                          FNCE 2024
                          Not Confirmed

                          Lead Product(s) : Oligonucleotide-based Therapeutics

                          Therapeutic Area : Genetic Disease

                          Study Phase : IND Enabling

                          Sponsor : SR One Capital Management

                          Deal Size : $75.0 million

                          Deal Type : Series B Financing

                          Details : The proceeds from the Series B financing will be used to advance ADARx’s proprietary RNA platform technologies for base editing, inhibition, degradation, and delivery.

                          Brand Name : Undisclosed

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          September 08, 2021

                          Lead Product(s) : Oligonucleotide-based Therapeutics

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : IND Enabling

                          Sponsor : SR One Capital Management

                          Deal Size : $75.0 million

                          Deal Type : Series B Financing

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